Quinazoline derivative from indigenous isolate,Nocardiopsis albainhibits human telomerase enzyme

Indolo[3,2-c]quinoline G-Quadruplex Stabilizers: a Structural Analysis of Binding to the Human Telomeric G-Quadruplex

(2015) João Lavrado et al.   ChemMedChem

The G-quadruplex-stabilising agent RHPS4 induces telomeric dysfunction and enhances radiosensitivity in glioblastoma cells

(2015) F. Berardinelli et al.   DNA REPAIR

Nocardiopsisspecies: a potential source of bioactive compounds

(2015) T. Bennur et al.   JOURNAL OF APPLIED MICROBIOLOGY

Human telomerase inhibitors from microbial source

(2015) Kalarikkal Gopikrishnan Kiran et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Isolation and diversity of natural product biosynthetic genes of cultivable bacteria associated with marine sponge Mycale sp. from the coast of Fujian, China

(2014) Pei Su et al.   CANADIAN JOURNAL OF MICROBIOLOGY

Mechanistic insight into ligand binding to G-quadruplex DNA

(2014) Francesco Saverio Di Leva et al.   NUCLEIC ACIDS RESEARCH

Recent Developments in Delivery, Bioavailability, Absorption and Metabolism of Curcumin: the Golden Pigment from Golden Spice

(2014) Sahdeo Prasad et al.   Cancer Research and Treatment

Potentially cytotoxic new copper(ii) hydrazone complexes: synthesis, crystal structure and biological properties

(2013) Mani Alagesan et al.   DALTON TRANSACTIONS

New quinazoline derivatives for telomeric G-quadruplex DNA: Effects of an added phenyl group on quadruplex binding ability

(2013) Jin-Hui He et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The Effect of Curcumin on Breast Cancer Cells

(2013) Dongwu Liu et al.   Journal of Breast Cancer

Structure, antimicrobial activity, DNA- and albumin-binding of manganese(II) complexes with the quinolone antimicrobial agents oxolinic acid and enrofloxacin

(2013) Marianthi Zampakou et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Identification of New Natural DNA G-Quadruplex Binders Selected by a Structure-Based Virtual Screening Approach

(2013) Anna Artese et al.   MOLECULES

Novel anticancer therapeutics targeting telomerase

(2012) Maria Ruden et al.   CANCER TREATMENT REVIEWS

A novel water soluble ligand bridged cobalt(ii) coordination polymer of 2-oxo-1,2-dihydroquinoline-3-carbaldehyde (isonicotinic) hydrazone: evaluation of the DNA binding, protein interaction, radical scavenging and anticancer activity

(2012) Duraisamy Senthil Raja et al.   DALTON TRANSACTIONS

New diketopiperazine derivatives from a deep-sea-derived Nocardiopsis alba SCSIO 03039

(2012) Qingbo Zhang et al.   JOURNAL OF ANTIBIOTICS

A novel anticancer and antifungus phenazine derivative from a marine actinomycete BM-17

(2012) Xiaochun Gao et al.   MICROBIOLOGICAL RESEARCH

G4LDB: a database for discovering and studying G-quadruplex ligands

(2012) Qian Li et al.   NUCLEIC ACIDS RESEARCH

Telomere-independent functions of telomerase in nuclei, cytoplasm, and mitochondria

(2012) Ilaria Chiodi et al.   Frontiers in Oncology

Benzamides and Quinazolines from a Mangrove Actinomycetes Streptomyces sp. (No. 061316) and Their Inhibiting Caspase-3 Catalytic Activity in Vitro

(2011) Guodong Chen et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Disubstituted quinazoline derivatives as a new type of highly selective ligands for telomeric G-quadruplex DNA

(2011) Zeng Li et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Farinamycin, a Quinazoline fromStreptomyces griseus

(2011) Markus Nett et al.   JOURNAL OF NATURAL PRODUCTS

Impact of planarity of unfused aromatic molecules on G-quadruplex binding: Learning from isaindigotone derivatives

(2011) Jin-Qiang Hou et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Human telomeric G-quadruplex: The current status of telomeric G-quadruplexes as therapeutic targets in human cancer

(2009) Stephen Neidle   FEBS Journal

Telomerase modulates Wnt signalling by association with target gene chromatin

(2009) Jae-Il Park et al.   NATURE

An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA

(2009) Yoshiko Maida et al.   NATURE

How Shelterin Protects Mammalian Telomeres

(2008) Wilhelm Palm et al.   Annual Review of Genetics