Journal
JOURNAL OF NATURAL PRODUCTS
Volume 74, Issue 10, Pages 2265-2268Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np2002513
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Funding
- Bundesministerium fur Bildung und Forschung [0315591A]
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The metabolic potential of a Streptomyces griseus strain was investigated under various cultivation conditions. After fermentation in a flour-based medium, a new quinazoline metabolite, farinamycin (1), could be isolated from the bacterium, which was previously known only for the production of phenoxazinone antibiotics. The structure of 1 illuminates the biosynthetic versatility of S. griseus, which assembles a defined set of building blocks into structurally diverse natural products.
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