Consequences of nano and microplastic exposure in rodent models: the known and unknown

Polystyrene microplastics lead to pyroptosis and apoptosis of ovarian granulosa cells via NLRP3/Caspase-1 signaling pathway in rats

(2021) Junyu Hou et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Newly Emerging Airborne Pollutants: Current Knowledge of Health Impact of Micro and Nanoplastics

(2021) Alessio Facciolà et al.   International Journal of Environmental Research and Public Health

Tissue distribution of polystyrene nanoplastics in mice and their entry, transport, and cytotoxicity to GES-1 cells

(2021) Yunfei Ding et al.   ENVIRONMENTAL POLLUTION

Toxic effects on bioaccumulation, hematological parameters, oxidative stress, immune responses and neurotoxicity in fish exposed to microplastics: A review

(2021) Jun-Hwan Kim et al.   JOURNAL OF HAZARDOUS MATERIALS

Polystyrene nanoplastics exposure caused defective neural tube morphogenesis through caveolae-mediated endocytosis and faulty apoptosis

(2021) Jia-hui Nie et al.   Nanotoxicology

Underestimated health risks: polystyrene micro- and nanoplastics jointly induce intestinal barrier dysfunction by ROS-mediated epithelial cell apoptosis

(2021) Boxuan Liang et al.   Particle and Fibre Toxicology

Polystyrene microplastics disturb maternal-fetal immune balance and cause reproductive toxicity in pregnant mice

(2021) Jianing Hu et al.   REPRODUCTIVE TOXICOLOGY

Polystyrene nanoparticles: Sources, occurrence in the environment, distribution in tissues, accumulation and toxicity to various organisms

(2020) Kinga Kik et al.   ENVIRONMENTAL POLLUTION

Toxicity of Microplastics and Nanoplastics in Mammalian Systems

(2020) Cheryl Qian Ying Yong et al.   International Journal of Environmental Research and Public Health

A Detailed Review Study on Potential Effects of Microplastics and Additives of Concern on Human Health

(2020) Campanale et al.   International Journal of Environmental Research and Public Health

Current Insights into Monitoring, Bioaccumulation, and Potential Health Effects of Microplastics Present in the Food Chain

(2020) Leonard W. D. van Raamsdonk et al.   Foods

Primary and Secondary Plastic Particles Exhibit Limited Acute Toxicity but Chronic Effects on Daphnia magna

(2020) Elvis Genbo Xu et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Readout of fluorescence functional signals through highly scattering tissue

(2020) Claudio Moretti et al.   Nature Photonics

Repeated-oral dose toxicity of polyethylene microplastics and the possible implications on reproduction and development of the next generation

(2020) Eun-Jung Park et al.   TOXICOLOGY LETTERS

Polystyrene microplastics decrease accumulation of essential fatty acids in common freshwater algae

(2020) Irina A. Guschina et al.   ENVIRONMENTAL POLLUTION

The emerging risk of exposure to nano(micro)plastics on endocrine disturbance and reproductive toxicity: From a hypothetical scenario to a global public health challenge

(2020) Fatemeh Amereh et al.   ENVIRONMENTAL POLLUTION

COVID-19 Pandemic Repercussions on the Use and Management of Plastics

(2020) Joana C. Prata et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

The plastic brain: neurotoxicity of micro- and nanoplastics

(2020) Minne Prüst et al.   Particle and Fibre Toxicology

Gut Microbiota in Liver Disease: What Do We Know and What Do We Not Know?

(2020) Lu Jiang et al.   PHYSIOLOGY

Chemical components of plastics as endocrine disruptors: Overview and commentary

(2020) Philippa D. Darbre   Birth Defects Research

Where is the evidence that human exposure to microplastics is safe?

(2020) H.A. Leslie et al.   ENVIRONMENT INTERNATIONAL

Polystyrene microplastics cause cardiac fibrosis by activating Wnt/β-catenin signaling pathway and promoting cardiomyocyte apoptosis in rats

(2020) Zekang Li et al.   ENVIRONMENTAL POLLUTION

Reproductive toxicity of polystyrene microplastics: In vivo experimental study on testicular toxicity in mice

(2020) Baolian Hou et al.   JOURNAL OF HAZARDOUS MATERIALS

Nanopolystyrene translocation and fetal deposition after acute lung exposure during late-stage pregnancy

(2020) Sara B. Fournier et al.   Particle and Fibre Toxicology

In vivo effects on the immune function of fathead minnow (Pimephales promelas) following ingestion and intraperitoneal injection of polystyrene nanoplastics

(2020) Armando Elizalde-Velázquez et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Proinflammatory properties and lipid disturbance of polystyrene microplastics in the livers of mice with acute colitis

(2020) Haibin Zheng et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Inhalation toxicity of polystyrene micro(nano)plastics using modified OECD TG 412

(2020) Dongyoung Lim et al.   CHEMOSPHERE

Keap1-Nrf2 pathway up-regulation via hydrogen sulfide mitigates polystyrene microplastics induced-hepatotoxic effects

(2020) Siwen Li et al.   JOURNAL OF HAZARDOUS MATERIALS

Polystyrene microplastics induced male reproductive toxicity in mice

(2020) Haibo Jin et al.   JOURNAL OF HAZARDOUS MATERIALS

Enhanced reproductive toxicities induced by phthalates contaminated microplastics in male mice (Mus musculus)

(2020) Yongfeng Deng et al.   JOURNAL OF HAZARDOUS MATERIALS

Micro- and nanoplastic induced cellular toxicity in mammals: A review

(2020) Amrita Banerjee et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Polystyrene microplastics cause granulosa cells apoptosis and fibrosis in ovary through oxidative stress in rats

(2020) Ru An et al.   TOXICOLOGY

Toxicity of polystyrene nanoplastics and zinc oxide to mice

(2020) Fernanda Neves Estrela et al.   CHEMOSPHERE

Plausibility of microplastic uptake in a paper by Deng et al., Scientific reports 7:46687, 2017

(2019) Linda Böhmert et al.   ARCHIVES OF TOXICOLOGY

Uptake and effects of orally ingested polystyrene microplastic particles in vitro and in vivo

(2019) Valerie Stock et al.   ARCHIVES OF TOXICOLOGY

Size-dependent effects of polystyrene microplastics on cytotoxicity and efflux pump inhibition in human Caco-2 cells

(2019) Bing Wu et al.   CHEMOSPHERE

Influence of nanoplastic surface charge on eco-corona formation, aggregation and toxicity to freshwater zooplankton

(2019) Juan Saavedra et al.   ENVIRONMENTAL POLLUTION

WHEN Fluorescence is not a particle: The tissue translocation of microplastics in Daphnia magna seems an artIfact

(2019) Christoph Schür et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Things we know and don’t know about nanoplastic in the environment

(2019) Stephan Wagner et al.   Nature Nanotechnology

Human Consumption of Microplastics

(2019) Kieran D. Cox et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Microplastics and the gut microbiome: How chronically exposed species may suffer from gut dysbiosis

(2019) Gloria Fackelmann et al.   MARINE POLLUTION BULLETIN

Interaction between microplastics and microorganism as well as gut microbiota: A consideration on environmental animal and human health

(2019) Liang Lu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Assessment on interactive prospectives of nanoplastics with plasma proteins and the toxicological impacts of virgin, coronated and environmentally released-nanoplastics

(2019) Ponnusamy Manogaran Gopinath et al.   Scientific Reports

Bioaccumulation in the gut and liver causes gut barrier dysfunction and hepatic metabolism disorder in mice after exposure to low doses of OBS

(2019) Caiyun Wang et al.   ENVIRONMENT INTERNATIONAL

Maternal Polystyrene Microplastic Exposure during Gestation and Lactation Altered Metabolic Homeostasis in the Dams and Their F1 and F2 Offspring

(2019) Ting Luo et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Molecular toxicity of nanoplastics involving in oxidative stress and desoxyribonucleic acid damage

(2019) Tongtong Zheng et al.   JOURNAL OF MOLECULAR RECOGNITION

Biological interactions between nanomaterials and placental development and function following oral exposure

(2019) Ninell P. Mortensen et al.   REPRODUCTIVE TOXICOLOGY

In Vitro Genotoxicity of Polystyrene Nanoparticles on the Human Fibroblast Hs27 Cell Line

(2019) Anna Poma et al.   Nanomaterials

Subchronic exposure of environmentally relevant concentrations of F-53B in mice resulted in gut barrier dysfunction and colonic inflammation in a sex-independent manner

(2019) Zihong Pan et al.   ENVIRONMENTAL POLLUTION

Impacts of plastic products used in daily life on the environment and human health: What is known?

(2019) M.O. Rodrigues et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Polystyrene Nanoparticles Reduced ROS and Inhibited Ferroptosis by Triggering Lysosome Stress and TFEB Nucleus Translocation in a Size-Dependent Manner

(2019) Lin Li et al.   NANO LETTERS

Interaction of particles with mucosae and cell membranes

(2019) Shaohuang Chen et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Exposure to polystyrene microplastics causes reproductive toxicity through oxidative stress and activation of the p38 MAPK signaling pathway

(2019) Xiaoman Xie et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Atmospheric microplastic deposition in an urban environment and an evaluation of transport

(2019) S.L. Wright et al.   ENVIRONMENT INTERNATIONAL

Maternal exposure to different sizes of polystyrene microplastics during gestation causes metabolic disorders in their offspring

(2019) Ting Luo et al.   ENVIRONMENTAL POLLUTION

Effects of polystyrene microbeads on cytotoxicity and transcriptomic profiles in human Caco‐2 cells

(2019) Shijin Wu et al.   ENVIRONMENTAL TOXICOLOGY

Potential health impact of environmental micro‐ and nanoplastics pollution

(2019) Xiaoru Chang et al.   JOURNAL OF APPLIED TOXICOLOGY

Polystyrene microplastic particles: In vitro pulmonary toxicity assessment

(2019) Cheng-Di Dong et al.   JOURNAL OF HAZARDOUS MATERIALS

Potential adverse health effects of ingested micro- and nanoplastics on humans. Lessons learned from in vivo and in vitro mammalian models

(2019) Laura Rubio et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Environmental exposure to microplastics: An overview on possible human health effects

(2019) Joana Correia Prata et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Polyethylene microplastics affect the distribution of gut microbiota and inflammation development in mice

(2019) Boqing Li et al.   CHEMOSPHERE

Neurobehavioral assessment of rats exposed to pristine polystyrene nanoplastics upon oral exposure

(2018) Mohammad Rafiee et al.   CHEMOSPHERE

Airborne microplastics: Consequences to human health?

(2018) Joana Correia Prata   ENVIRONMENTAL POLLUTION

An overview of chemical additives present in plastics: Migration, release, fate and environmental impact during their use, disposal and recycling

(2018) John N. Hahladakis et al.   JOURNAL OF HAZARDOUS MATERIALS

Evidence that microplastics aggravate the toxicity of organophosphorus flame retardants in mice ( Mus musculus )

(2018) Yongfeng Deng et al.   JOURNAL OF HAZARDOUS MATERIALS

Plastic contamination of the food chain: A threat to human health?

(2018) R.H. Waring et al.   MATURITAS

Microplastics research—from sink to source

(2018) Chelsea M. Rochman   SCIENCE

Polystyrene microplastics induce gut microbiota dysbiosis and hepatic lipid metabolism disorder in mice

(2018) Liang Lu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

A critical perspective on early communications concerning human health aspects of microplastics

(2018) Sinja Rist et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Uptake, Whole-Body Distribution, and Depuration of Nanoplastics by the Scallop Pecten maximus at Environmentally Realistic Concentrations

(2018) Maya Al-Sid-Cheikh et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Impacts of polystyrene microplastic on the gut barrier, microbiota and metabolism of mice

(2018) Yuanxiang Jin et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Toxicity-based toxicokinetic/toxicodynamic assessment for bioaccumulation of polystyrene microplastics in mice

(2018) Ying-Fei Yang et al.   JOURNAL OF HAZARDOUS MATERIALS

Distribution and importance of microplastics in the marine environment: A review of the sources, fate, effects, and potential solutions

(2017) H.S. Auta et al.   ENVIRONMENT INTERNATIONAL

Cytotoxic effects of commonly used nanomaterials and microplastics on cerebral and epithelial human cells

(2017) Gabriella F. Schirinzi et al.   ENVIRONMENTAL RESEARCH

Plastic and Human Health: A Micro Issue?

(2017) Stephanie L. Wright et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Plastic bodies in a plastic world: multi-disciplinary approaches to study endocrine disrupting chemicals

(2017) Laura N. Vandenberg et al.   JOURNAL OF CLEANER PRODUCTION

Interactions of microplastic debris throughout the marine ecosystem

(2017) Tamara S. Galloway et al.   Nature Ecology & Evolution

Tissue accumulation of microplastics in mice and biomarker responses suggest widespread health risks of exposure

(2017) Yongfeng Deng et al.   Scientific Reports

Is there any consistency between the microplastics found in the field and those used in laboratory experiments?

(2016) Nam Ngoc Phuong et al.   ENVIRONMENTAL POLLUTION

Toxicity and inflammatory response in Swiss albino mice after intraperitoneal and oral administration of polyurethane nanoparticles

(2016) Adny H. Silva et al.   TOXICOLOGY LETTERS

Bioavailability and biodistribution of differently charged polystyrene nanoparticles upon oral exposure in rats

(2015) Agata P. Walczak et al.   JOURNAL OF NANOPARTICLE RESEARCH

Neurotoxicity induced by zinc oxide nanoparticles: age-related differences and interaction

(2015) Lei Tian et al.   Scientific Reports

Objective assessment of nanoparticle disposition in mammalian skin after topical exposure

(2012) Christopher S.J. Campbell et al.   JOURNAL OF CONTROLLED RELEASE

In Vivo Skin Penetration of Quantum Dot Nanoparticles in the Murine Model: The Effect of UVR

(2008) Luke J. Mortensen et al.   NANO LETTERS