HO-1 Contributes to Luteolin-Triggered Ferroptosis in Clear Cell Renal Cell Carcinoma via Increasing the Labile Iron Pool and Promoting Lipid Peroxidation

Double-edge sword roles of iron in driving energy production versus instigating ferroptosis

(2022) Shuping Zhang et al.   Cell Death & Disease

Emerging mechanisms and targeted therapy of ferroptosis in cancer

(2021) Haiyan Wang et al.   MOLECULAR THERAPY

ATF3 contributes to brucine-triggered glioma cell ferroptosis via promotion of hydrogen peroxide and iron

(2021) Shan Lu et al.   ACTA PHARMACOLOGICA SINICA

KLF2 inhibits cancer cell migration and invasion by regulating ferroptosis through GPX4 in clear cell renal cell carcinoma

(2021) Yingqiang Lu et al.   CANCER LETTERS

Luteolin prevents irinotecan‐induced intestinal mucositis in mice through antioxidant and anti‐inflammatory properties

(2020) Thaise Boeing et al.   BRITISH JOURNAL OF PHARMACOLOGY

Nrf2 inhibits ferroptosis and protects against acute lung injury due to intestinal ischemia reperfusion via regulating SLC7A11 and HO-1

(2020) Hui Dong et al.   Aging-US

Plasticity of ether lipids promotes ferroptosis susceptibility and evasion

(2020) Yilong Zou et al.   NATURE

The Application of Ferroptosis in Diseases

(2020) Yangmin Qiu et al.   PHARMACOLOGICAL RESEARCH

SUV39H1 deficiency suppresses clear cell renal cell carcinoma growth by inducing ferroptosis

(2020) Jianfeng Wang et al.   Acta Pharmaceutica Sinica B

Transcriptome Investigation and In Vitro Verification of Curcumin-Induced HO-1 as a Feature of Ferroptosis in Breast Cancer Cells

(2020) Ruihua Li et al.   Oxidative Medicine and Cellular Longevity

Protective role of microglial HO-1 blockade in aging: Implication of iron metabolism

(2020) Cristina Fernández-Mendívil et al.   Redox Biology

Decrease of AIM2 mediated by luteolin contributes to non-small cell lung cancer treatment

(2019) Qian Yu et al.   Cell Death & Disease

Ferroptosis as a target for protection against cardiomyopathy

(2019) Xuexian Fang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ischemia-induced ACSL4 activation contributes to ferroptosis-mediated tissue injury in intestinal ischemia/reperfusion

(2019) Yang Li et al.   CELL DEATH AND DIFFERENTIATION

Luteolin, a flavonoid, as an anticancer agent: A review

(2019) Muhammad Imran et al.   BIOMEDICINE & PHARMACOTHERAPY

Artemisinin compounds sensitize cancer cells to ferroptosis by regulating iron homeostasis

(2019) Guo-Qing Chen et al.   CELL DEATH AND DIFFERENTIATION

Betula etnensis Raf. (Betulaceae) Extract Induced HO-1 Expression and Ferroptosis Cell Death in Human Colon Cancer Cells

(2019) Giuseppe Antonio Malfa et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The multifaceted role of iron in renal health and disease

(2019) Rachel P. L. van Swelm et al.   Nature Reviews Nephrology

The Hippo Pathway Effector TAZ Regulates Ferroptosis in Renal Cell Carcinoma

(2019) Wen-Hsuan Yang et al.   Cell Reports

Heme oxygenase-1 mediates BAY 11–7085 induced ferroptosis

(2018) Ling-Chu Chang et al.   CANCER LETTERS

Current and Emerging Therapies for First-Line Treatment of Metastatic Clear Cell Renal Cell Carcinoma

(2018) Michael B. Atkins et al.   CANCER TREATMENT REVIEWS

A review on heme oxygenase-1 induction: is it a necessary evil

(2018) Ajaz Ahmad Waza et al.   INFLAMMATION RESEARCH

Epidemiology of Renal Cell Carcinoma

(2018) Umberto Capitanio et al.   EUROPEAN UROLOGY

The sinister face of heme oxygenase-1 in brain aging and disease

(2018) Hyman M. Schipper et al.   PROGRESS IN NEUROBIOLOGY

Nrf2 inhibition reverses resistance to GPX4 inhibitor-induced ferroptosis in head and neck cancer

(2018) Daiha Shin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Renal Mass and Localized Renal Cancer: AUA Guideline

(2017) Steven Campbell et al.   JOURNAL OF UROLOGY

Iron and cancer: recent insights

(2016) David H. Manz et al.   Annals of the New York Academy of Sciences

Luteolin inhibits viral-induced inflammatory response in RAW264.7 cells via suppression of STAT1/3 dependent NF-κB and activation of HO-1

(2016) Cheng-Wei Liu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Ferroptosis: Death by Lipid Peroxidation

(2016) Wan Seok Yang et al.   TRENDS IN CELL BIOLOGY

Luteolin sensitizes human 786-O renal cell carcinoma cells to TRAIL-induced apoptosis

(2014) Yen-Chuan Ou et al.   LIFE SCIENCES

Induction of Apoptosis by Luteolin Involving Akt Inactivation in Human 786-O Renal Cell Carcinoma Cells

(2013) Yen-Chuan Ou et al.   Evidence-based Complementary and Alternative Medicine

Luteolin and luteolin-7-O-glucoside strengthen antioxidative potential through the modulation of Nrf2/MAPK mediated HO-1 signaling cascade in RAW 264.7 cells

(2013) Young Sun Song et al.   FOOD AND CHEMICAL TOXICOLOGY

Modulation of oxidative stress as an anticancer strategy

(2013) Chiara Gorrini et al.   NATURE REVIEWS DRUG DISCOVERY

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Mechanisms of Cell Protection by Heme Oxygenase-1

(2010) Raffaella Gozzelino et al.   Annual Review of Pharmacology and Toxicology

Heme Degradation and Vascular Injury

(2009) John D. Belcher et al.   ANTIOXIDANTS & REDOX SIGNALING

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

(2009) Oleg Trott et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY