Glycyrrhizin Attenuates Hypoxic-Ischemic Brain Damage by Inhibiting Ferroptosis and Neuroinflammation in Neonatal Rats via the HMGB1/GPX4 Pathway

Neferine Protects against Hypoxic-Ischemic Brain Damage in Neonatal Rats by Suppressing NLRP3-Mediated Inflammasome Activation

(2021) Jin-jin Zhu et al.   Oxidative Medicine and Cellular Longevity

Neuroprotective Effects of Oxymatrine on PI3K/Akt/mTOR Pathway After Hypoxic-Ischemic Brain Damage in Neonatal Rats

(2021) Wei Wei et al.   Frontiers in Pharmacology

Inhibition of TLR4 prevents hippocampal hypoxic-ischemic injury by regulating ferroptosis in neonatal rats

(2021) Kaiyi Zhu et al.   EXPERIMENTAL NEUROLOGY

Alarmin HMGB1 Plays a Detrimental Role in Hippocampal Dysfunction Caused by Hypoxia-Ischemia Insult in Neonatal Mice: Evidence from the Application of the HMGB1 Inhibitor Glycyrrhizin

(2020) Kai Le et al.   ACS Chemical Neuroscience

The circadian clock protects against ferroptosis-induced sterile inflammation

(2020) Yang Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Energy-stress-mediated AMPK activation inhibits ferroptosis

(2020) Hyemin Lee et al.   NATURE CELL BIOLOGY

Glycyrrhizin Prevents Hemorrhagic Transformation and Improves Neurological Outcome in Ischemic Stroke with Delayed Thrombolysis Through Targeting Peroxynitrite-Mediated HMGB1 Signaling

(2020) Hansen Chen et al.   Translational Stroke Research

Circular RNA cZNF292 silence alleviates OGD/R-induced injury through up-regulation of miR-22 in rat neural stem cells (NSCs)

(2020) Yaqin Cao et al.   Artificial Cells Nanomedicine and Biotechnology

Glycyrrhizic acid exerts protective effects against hypoxia/reoxygenation‑induced human coronary artery endothelial cell damage by regulating mitochondria

(2020) Quan Tang et al.   Experimental and Therapeutic Medicine

The emerging role of ferroptosis in inflammation

(2020) Yitian Sun et al.   BIOMEDICINE & PHARMACOTHERAPY

Extract of Naotaifang, a compound Chinese herbal medicine, protects neuron ferroptosis induced by acute cerebral ischemia in rats

(2020) Bin Lan et al.   Journal of Integrative Medicine-JIM

Melatonin improves hypoxic-ischemic brain damage through the Akt/Nrf2/Gpx4 signaling pathway

(2020) Zhixian Gou et al.   BRAIN RESEARCH BULLETIN

Ischemia-induced ACSL4 activation contributes to ferroptosis-mediated tissue injury in intestinal ischemia/reperfusion

(2019) Yang Li et al.   CELL DEATH AND DIFFERENTIATION

Selenium Drives a Transcriptional Adaptive Program to Block Ferroptosis and Treat Stroke

(2019) Ishraq Alim et al.   CELL

Effect of HMGB1 and RAGE on brain injury and the protective mechanism of glycyrrhizin in intracranial‑sinus occlusion followed by mechanical thrombectomy recanalization

(2019) Shu‑Wen Mu et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Hepatic ferroptosis plays an important role as the trigger for initiating inflammation in nonalcoholic steatohepatitis

(2019) Shinya Tsurusaki et al.   Cell Death & Disease

Role of TLR4/NADPH oxidase 4 pathway in promoting cell death through autophagy and ferroptosis during heart failure

(2019) Xiaoqing Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Neuroprotective effect of Vanillin on hypoxic-ischemic brain damage in neonatal rats

(2019) Xiao-Bing Lan et al.   BIOMEDICINE & PHARMACOTHERAPY

Early TLR4 inhibition reduces hippocampal injury at puberty in a rat model of neonatal hypoxic-ischemic brain damage via regulation of neuroimmunity and synaptic plasticity

(2019) Zhen Tang et al.   EXPERIMENTAL NEUROLOGY

The neuroprotective effects of carvacrol on ischemia/reperfusion-induced hippocampal neuronal impairment by ferroptosis mitigation

(2019) Xueying Guan et al.   LIFE SCIENCES

FSP1 is a glutathione-independent ferroptosis suppressor

(2019) Sebastian Doll et al.   NATURE

ROS-mediated autophagy increases intracellular iron levels and ferroptosis by ferritin and transferrin receptor regulation

(2019) Eunhee Park et al.   Cell Death & Disease

Arsenic induces pancreatic dysfunction and ferroptosis via mitochondrial ROS-autophagy-lysosomal pathway

(2019) Sen Wei et al.   JOURNAL OF HAZARDOUS MATERIALS

High-Mobility Group Box 1 Contributes to Cerebral Cortex Injury in a Neonatal Hypoxic-Ischemic Rat Model by Regulating the Phenotypic Polarization of Microglia

(2019) Yanyan Sun et al.   Frontiers in Cellular Neuroscience

Pseudolaric acid B triggers ferroptosis in glioma cells via activation of Nox4 and inhibition of xCT

(2018) Zongqi Wang et al.   CANCER LETTERS

HMGB1 a-Box Reverses Brain Edema and Deterioration of Neurological Function in a Traumatic Brain Injury Mouse Model

(2018) Lijun Yang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Mitochondrial rescue prevents glutathione peroxidase-dependent ferroptosis

(2018) Anja Jelinek et al.   FREE RADICAL BIOLOGY AND MEDICINE

Vitexin reduces epilepsy after hypoxic ischemia in the neonatal brain via inhibition of NKCC1

(2018) Wen-di Luo et al.   Journal of Neuroinflammation

Vitamin A bio-modulates apoptosis via the mitochondrial pathway after hypoxic-ischemic brain damage

(2018) Wei Jiang et al.   Molecular Brain

Inhibition of ferroptosis attenuates tissue damage and improves long-term outcomes after traumatic brain injury in mice

(2018) Bao-Shu Xie et al.   CNS Neuroscience & Therapeutics

Compound Ammonium Glycyrrhizin Protects Hepatocytes from Injury Induced by Lipopolysaccharide/Florfenicol through a Mitochondrial Pathway

(2018) Wenyang Li et al.   MOLECULES

Ferroptosis Contributes to Neuronal Death and Functional Outcome After Traumatic Brain Injury

(2018) Elizabeth M. Kenny et al.   CRITICAL CARE MEDICINE

High-mobility group box-1 translocation and release after hypoxic ischemic brain injury in neonatal rats

(2018) Xiaodi Chen et al.   EXPERIMENTAL NEUROLOGY

RSL3 Drives Ferroptosis Through GPX4 Inactivation and ROS Production in Colorectal Cancer

(2018) Xinbing Sui et al.   Frontiers in Pharmacology

Tau-mediated iron export prevents ferroptotic damage after ischemic stroke

(2017) Q-z Tuo et al.   MOLECULAR PSYCHIATRY

Tanshinone I alleviates motor and cognitive impairments via suppressing oxidative stress in the neonatal rats after hypoxic-ischemic brain damage

(2017) Chunfang Dai et al.   Molecular Brain

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

(2016) Sebastian Doll et al.   Nature Chemical Biology

Oxidative Inactivation of Liver Mitochondria in High Fructose Diet-Induced Metabolic Syndrome in Rats: Effect of Glycyrrhizin Treatment

(2016) Rajarshi Sil et al.   PHYTOTHERAPY RESEARCH

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL