Breaking trade-offs: Development of fast, high-resolution, wide-field two-photon microscopes to reveal the computational principles of the brain

Temporally multiplexed dual-plane imaging of neural activity with four-dimensional precision

(2021) Masanari Onda et al.   NEUROSCIENCE RESEARCH

High-precision coding in visual cortex

(2021) Carsen Stringer et al.   CELL

Fast, cell-resolution, contiguous-wide two-photon imaging to reveal functional network architectures across multi-modal cortical areas

(2021) Keisuke Ota et al.   NEURON

Rapid suppression and sustained activation of distinct cortical regions for a delayed sensory-triggered motor response

(2021) Vahid Esmaeili et al.   NEURON

Flexible simultaneous mesoscale two-photon imaging of neural activity at high speeds

(2021) Mitchell Clough et al.   Nature Communications

Diesel2p mesoscope with dual independent scan engines for flexible capture of dynamics in distributed neural circuitry

(2021) Che-Hang Yu et al.   Nature Communications

Recurrent interactions in local cortical circuits

(2020) Simon Peron et al.   NATURE

Kilohertz two-photon fluorescence microscopy imaging of neural activity in vivo

(2020) Jianglai Wu et al.   NATURE METHODS

Rapid mesoscale volumetric imaging of neural activity with synaptic resolution

(2020) Rongwen Lu et al.   NATURE METHODS

Fundamental bounds on the fidelity of sensory cortical coding

(2020) Oleg I. Rumyantsev et al.   NATURE

Targeted Activation of Hippocampal Place Cells Drives Memory-Guided Spatial Behavior

(2020) Nick T.M. Robinson et al.   CELL

Functional imaging of visual cortical layers and subplate in awake mice with optimized three-photon microscopy

(2019) Murat Yildirim et al.   Nature Communications

Single-neuron perturbations reveal feature-specific competition in V1

(2019) Selmaan N. Chettih et al.   NATURE

Volumetric Ca2+ Imaging in the Mouse Brain Using Hybrid Multiplexed Sculpted Light Microscopy

(2019) Siegfried Weisenburger et al.   CELL

Spontaneous behaviors drive multidimensional, brainwide activity

(2019) Carsen Stringer et al.   SCIENCE

Two-Color Volumetric Imaging of Neuronal Activity of Cortical Columns

(2019) Shuting Han et al.   Cell Reports

Controlling Visually Guided Behavior by Holographic Recalling of Cortical Ensembles

(2019) Luis Carrillo-Reid et al.   CELL

High-dimensional geometry of population responses in visual cortex

(2019) Carsen Stringer et al.   NATURE

High-performance calcium sensors for imaging activity in neuronal populations and microcompartments

(2019) Hod Dana et al.   NATURE METHODS

Single-trial neural dynamics are dominated by richly varied movements

(2019) Simon Musall et al.   NATURE NEUROSCIENCE

Wide. Fast. Deep: Recent Advances in Multiphoton Microscopy of In Vivo Neuronal Activity

(2019) Jérôme Lecoq et al.   JOURNAL OF NEUROSCIENCE

Excitatory Neuronal Hubs Configure Multisensory Integration of Slow Waves in Association Cortex

(2018) Satoshi Kuroki et al.   Cell Reports

Thalamocortical Axonal Activity in Motor Cortex Exhibits Layer-Specific Dynamics during Motor Learning

(2018) Yasuyo H. Tanaka et al.   NEURON

Behavioral Strategy Determines Frontal or Posterior Location of Short-Term Memory in Neocortex

(2018) Ariel Gilad et al.   NEURON

Super-wide-field two-photon imaging with a micro-optical device moving in post-objective space

(2018) Shin-Ichiro Terada et al.   Nature Communications

Fully integrated silicon probes for high-density recording of neural activity

(2017) James J. Jun et al.   NATURE

In vivo imaging of neural activity

(2017) Weijian Yang et al.   NATURE METHODS

Fast high-resolution miniature two-photon microscopy for brain imaging in freely behaving mice

(2017) Weijian Zong et al.   NATURE METHODS

In vivo three-photon imaging of activity of GCaMP6-labeled neurons deep in intact mouse brain

(2017) Dimitre G Ouzounov et al.   NATURE METHODS

An inhibitory pull–push circuit in frontal cortex

(2017) Pablo Garcia-Junco-Clemente et al.   NATURE NEUROSCIENCE

Global Representations of Goal-Directed Behavior in Distinct Cell Types of Mouse Neocortex

(2017) William E. Allen et al.   NEURON

AAV-Mediated Anterograde Transsynaptic Tagging: Mapping Corticocollicular Input-Defined Neural Pathways for Defense Behaviors

(2017) Brian Zingg et al.   NEURON

Long-Term Two-Photon Imaging in Awake Macaque Monkey

(2017) Ming Li et al.   NEURON

Surround Integration Organizes a Spatial Map during Active Sensation

(2017) Scott R. Pluta et al.   NEURON

Transformation of Cortex-wide Emergent Properties during Motor Learning

(2017) Hiroshi Makino et al.   NEURON

Lattice system of functionally distinct cell types in the neocortex

(2017) Hisato Maruoka et al.   SCIENCE

Brain heating induced by near-infrared lasers during multiphoton microscopy

(2016) Kaspar Podgorski et al.   JOURNAL OF NEUROPHYSIOLOGY

Active cortical dendrites modulate perception

(2016) Naoya Takahashi et al.   SCIENCE

A large field of view two-photon mesoscope with subcellular resolution for in vivo imaging

(2016) Nicholas James Sofroniew et al.   eLife

Viral-genetic tracing of the input–output organization of a central noradrenaline circuit

(2015) Lindsay A. Schwarz et al.   NATURE

A Top-Down Cortical Circuit for Accurate Sensory Perception

(2015) Satoshi Manita et al.   NEURON

Ultra-large field-of-view two-photon microscopy

(2015) Philbert S. Tsai et al.   OPTICS EXPRESS

In Vivo Monosynaptic Excitatory Transmission between Layer 2 Cortical Pyramidal Neurons

(2015) Jean-Sébastien Jouhanneau et al.   Cell Reports

Long-Term Two-Photon Calcium Imaging of Neuronal Populations with Subcellular Resolution in Adult Non-human Primates

(2015) Osamu Sadakane et al.   Cell Reports

Visualizing mammalian brain area interactions by dual-axis two-photon calcium imaging

(2014) Jérôme Lecoq et al.   NATURE NEUROSCIENCE

The log-dynamic brain: how skewed distributions affect network operations

(2014) György Buzsáki et al.   NATURE REVIEWS NEUROSCIENCE

Long-range and local circuits for top-down modulation of visual cortex processing

(2014) S. Zhang et al.   SCIENCE

Ultrasensitive fluorescent proteins for imaging neuronal activity

(2013) Tsai-Wen Chen et al.   NATURE

Spontaneous cortical activity alternates between motifs defined by regional axonal projections

(2013) Majid H Mohajerani et al.   NATURE NEUROSCIENCE

Choice-specific sequences in parietal cortex during a virtual-navigation decision task

(2012) Christopher D. Harvey et al.   NATURE

Fast two-photon in vivo imaging with three-dimensional random-access scanning in large tissue volumes

(2012) Gergely Katona et al.   NATURE METHODS

Synaptic Mechanisms Underlying Sparse Coding of Active Touch

(2011) Sylvain Crochet et al.   NEURON

Mirrored Bilateral Slow-Wave Cortical Activity within Local Circuits Revealed by Fast Bihemispheric Voltage-Sensitive Dye Imaging in Anesthetized and Awake Mice

(2010) M. H. Mohajerani et al.   JOURNAL OF NEUROSCIENCE

Dendritic organization of sensory input to cortical neurons in vivo

(2010) Hongbo Jia et al.   NATURE

The subcellular organization of neocortical excitatory connections

(2009) Leopoldo Petreanu et al.   NATURE

Long-term, high-resolution imaging in the mouse neocortex through a chronic cranial window

(2009) Anthony Holtmaat et al.   Nature Protocols

Internal brain state regulates membrane potential synchrony in barrel cortex of behaving mice

(2008) James F. A. Poulet et al.   NATURE