IL-1 and IL-1ra are key regulators of the inflammatory response to RNA vaccines
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
IL-1 and IL-1ra are key regulators of the inflammatory response to RNA vaccines
Authors
Keywords
-
Journal
NATURE IMMUNOLOGY
Volume 23, Issue 4, Pages 532-542
Publisher
Springer Science and Business Media LLC
Online
2022-03-25
DOI
10.1038/s41590-022-01160-y
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Correction to: circRIP2 accelerates bladder cancer progression via miR-1305/Tgf-β2/smad3 pathway
- (2021) Yinjie Su et al. Molecular Cancer
- A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
- (2021) Christina Krienke et al. SCIENCE
- Interleukin-1 as Innate Mediator of T Cell Immunity
- (2021) Bram Van Den Eeckhout et al. Frontiers in Immunology
- Immune Responses Induced by mRNA Vaccination in Mice, Monkeys and Humans
- (2021) Alberto Cagigi et al. Vaccines
- Nanomaterial Delivery Systems for mRNA Vaccines
- (2021) Michael D. Buschmann et al. Vaccines
- Delivery of mRNA vaccine with a lipid-like material potentiates antitumor efficacy through Toll-like receptor 4 signaling
- (2021) Hongxia Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Primate innate immune responses to bacterial and viral pathogens reveals an evolutionary trade-off between strength and specificity
- (2021) Mohamed B. F. Hawash et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The mRNA-LNP platform's lipid nanoparticle component used in preclinical vaccine studies is highly inflammatory
- (2021) Sonia Ndeupen et al. iScience
- Phase 1/2 study of COVID-19 RNA vaccine BNT162b1 in adults
- (2020) Mark J. Mulligan et al. NATURE
- An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma
- (2020) Ugur Sahin et al. NATURE
- An mRNA Vaccine against SARS-CoV-2 — Preliminary Report
- (2020) Lisa A. Jackson et al. NEW ENGLAND JOURNAL OF MEDICINE
- Early IL-1 receptor blockade in severe inflammatory respiratory failure complicating COVID-19
- (2020) Raphaël Cauchois et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Impact of mRNA chemistry and manufacturing process on innate immune activation
- (2020) Jennifer Nelson et al. Science Advances
- mRNA vaccine–induced neoantigen-specific T cell immunity in patients with gastrointestinal cancer
- (2020) Gal Cafri et al. JOURNAL OF CLINICAL INVESTIGATION
- COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T cell responses
- (2020) Ugur Sahin et al. NATURE
- Aquaporin-3 regulates endosome-to-cytosol transfer via lipid peroxidation for cross presentation
- (2020) Sam C. Nalle et al. PLoS One
- A Facile Method for the Removal of dsRNA Contaminant from In Vitro-Transcribed mRNA
- (2019) Markus Baiersdörfer et al. Molecular Therapy-Nucleic Acids
- Delivery of mRNA vaccines with heterocyclic lipids increases anti-tumor efficacy by STING-mediated immune cell activation
- (2019) Lei Miao et al. NATURE BIOTECHNOLOGY
- CD3 bispecific antibody–induced cytokine release is dispensable for cytotoxic T cell activity
- (2019) Ji Li et al. Science Translational Medicine
- Type I interferon-driven susceptibility to Mycobacterium tuberculosis is mediated by IL-1Ra
- (2019) Daisy X. Ji et al. Nature Microbiology
- A Novel Amino Lipid Series for mRNA Delivery: Improved Endosomal Escape and Sustained Pharmacology and Safety in Non-human Primates
- (2018) Staci Sabnis et al. MOLECULAR THERAPY
- Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells
- (2018) Margherita Norelli et al. NATURE MEDICINE
- CAR T cell–induced cytokine release syndrome is mediated by macrophages and abated by IL-1 blockade
- (2018) Theodoros Giavridis et al. NATURE MEDICINE
- mRNA vaccines — a new era in vaccinology
- (2018) Norbert Pardi et al. NATURE REVIEWS DRUG DISCOVERY
- Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy
- (2016) Lena M. Kranz et al. NATURE
- An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells
- (2016) Ivan Zanoni et al. SCIENCE
- Toxicity and management in CAR T-cell therapy
- (2016) Challice L Bonifant et al. Molecular Therapy-Oncolytics
- Efficacy and safety of CDX-301, recombinant human Flt3L, at expanding dendritic cells and hematopoietic stem cells in healthy human volunteers
- (2015) N Anandasabapathy et al. BONE MARROW TRANSPLANTATION
- Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
- (2015) Nobuhiko Kayagaki et al. NATURE
- Discordant Biological and Toxicological Species Responses to TLR3 Activation
- (2014) William M. Mitchell et al. AMERICAN JOURNAL OF PATHOLOGY
- Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing
- (2014) Mahesh Yadav et al. NATURE
- Cationic lipid nanocarriers activate Toll-like receptor 2 and NLRP3 inflammasome pathways
- (2013) Caroline Lonez et al. Nanomedicine-Nanotechnology Biology and Medicine
- Genomic responses in mouse models poorly mimic human inflammatory diseases
- (2013) Junhee Seok et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- IL-1 pathways in inflammation and human diseases
- (2010) Cem Gabay et al. Nature Reviews Rheumatology
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More