Region-based analysis of rare genomic variants in whole-genome sequencing datasets reveal two novel Alzheimer’s disease-associated genes: DTNB and DLG2
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Title
Region-based analysis of rare genomic variants in whole-genome sequencing datasets reveal two novel Alzheimer’s disease-associated genes: DTNB and DLG2
Authors
Keywords
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Journal
MOLECULAR PSYCHIATRY
Volume 27, Issue 4, Pages 1963-1969
Publisher
Springer Science and Business Media LLC
Online
2022-03-04
DOI
10.1038/s41380-022-01475-0
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Note: Only part of the references are listed.- Whole‐genome sequencing reveals new Alzheimer's disease–associated rare variants in loci related to synaptic function and neuronal development
- (2021) Dmitry Prokopenko et al. Alzheimers & Dementia
- A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer’s disease
- (2021) Douglas P. Wightman et al. NATURE GENETICS
- The mutational constraint spectrum quantified from variation in 141,456 humans
- (2020) Konrad J. Karczewski et al. NATURE
- Identification of Novel Alzheimer’s Disease Loci Using Sex-Specific Family-Based Association Analysis of Whole-Genome Sequence Data
- (2020) Dmitry Prokopenko et al. Scientific Reports
- The endogenous neuronal complement inhibitor SRPX2 protects against complement-mediated synapse elimination during development
- (2020) Qifei Cong et al. NATURE NEUROSCIENCE
- A unifying framework for rare variant association testing in family-based designs, including higher criticism approaches, SKATs, and burden tests
- (2020) Julian Hecker et al. BIOINFORMATICS
- Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype
- (2019) Yiyi Ma et al. JAMA Neurology
- Inherited and De Novo Genetic Risk for Autism Impacts Shared Networks
- (2019) Elizabeth K. Ruzzo et al. CELL
- Sex differences in brain structure: a twin study on restricted and repetitive behaviors in twin pairs with and without autism
- (2019) Annelies van’t Westeinde et al. Molecular Autism
- Synaptic Proteome Compensation and Resilience to Psychosis in Alzheimer’s Disease
- (2018) Josh M. Krivinko et al. AMERICAN JOURNAL OF PSYCHIATRY
- A Longitudinal Imaging Genetics Study of Neuroanatomical Asymmetry in Alzheimer’s Disease
- (2018) Christian Wachinger et al. BIOLOGICAL PSYCHIATRY
- Postsynaptic density proteins and their involvement in neurodevelopmental disorders
- (2018) Takeshi Kaizuka et al. JOURNAL OF BIOCHEMISTRY
- Whole-exome sequencing of the BDR cohort: evidence to support the role of the PILRA gene in Alzheimer's disease
- (2018) T. Patel et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Whole-exome sequencing in 20,197 persons for rare variants in Alzheimer's disease
- (2018) Neha S. Raghavan et al. Annals of Clinical and Translational Neurology
- Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation
- (2018) Joshua C. Bis et al. MOLECULAR PSYCHIATRY
- VCPA: genomic variant calling pipeline and data management tool for Alzheimer’s Disease Sequencing Project
- (2018) Yuk Yee Leung et al. BIOINFORMATICS
- Cytoscape StringApp: Network Analysis and Visualization of Proteomics Data
- (2018) Nadezhda T. Doncheva et al. JOURNAL OF PROTEOME RESEARCH
- STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
- (2018) Damian Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019
- (2018) Annalisa Buniello et al. NUCLEIC ACIDS RESEARCH
- Family-based tests for associating haplotypes with general phenotype data
- (2017) Julian Hecker et al. GENETIC EPIDEMIOLOGY
- The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease
- (2015) Christina M. Lill et al. Alzheimers & Dementia
- Utilizing the Jaccard index to reveal population stratification in sequencing data: a simulation study and an application to the 1000 Genomes Project
- (2015) Dmitry Prokopenko et al. BIOINFORMATICS
- Tissue-based map of the human proteome
- (2015) M. Uhlen et al. SCIENCE
- Expression analysis in a rat psychosis model identifies novel candidate genes validated in a large case–control sample of schizophrenia
- (2015) A Ingason et al. Translational Psychiatry
- Identification of risk genes for autism spectrum disorder through copy number variation analysis in Austrian families
- (2014) Gerald Egger et al. NEUROGENETICS
- Rare Variant Analysis for Family-Based Design
- (2013) Gourab De et al. PLoS One
- Optimal Unified Approach for Rare-Variant Association Testing with Application to Small-Sample Case-Control Whole-Exome Sequencing Studies
- (2012) Seunggeun Lee et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Association of genetic variations in DTNBP1 with cognitive function in schizophrenia patients and healthy subjects
- (2012) Ji Hyun Baek et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- Snakemake--a scalable bioinformatics workflow engine
- (2012) J. Koster et al. BIOINFORMATICS
- Estimation and partitioning of polygenic variation captured by common SNPs for Alzheimer's disease, multiple sclerosis and endometriosis
- (2012) S. H. Lee et al. HUMAN MOLECULAR GENETICS
- Wnt Signaling: Role in Alzheimer Disease and Schizophrenia
- (2012) Nibaldo C. Inestrosa et al. Journal of Neuroimmune Pharmacology
- Synaptic genes are extensively downregulated across multiple brain regions in normal human aging and Alzheimer's disease
- (2012) Nicole C. Berchtold et al. NEUROBIOLOGY OF AGING
- Variant of TREM2 Associated with the Risk of Alzheimer's Disease
- (2012) Thorlakur Jonsson et al. NEW ENGLAND JOURNAL OF MEDICINE
- TREM2 Variants in Alzheimer's Disease
- (2012) Rita Guerreiro et al. NEW ENGLAND JOURNAL OF MEDICINE
- STRING v9.1: protein-protein interaction networks, with increased coverage and integration
- (2012) Andrea Franceschini et al. NUCLEIC ACIDS RESEARCH
- NCBI GEO: archive for functional genomics data sets—update
- (2012) Tanya Barrett et al. NUCLEIC ACIDS RESEARCH
- Rare-Variant Association Testing for Sequencing Data with the Sequence Kernel Association Test
- (2011) Michael C. Wu et al. AMERICAN JOURNAL OF HUMAN GENETICS
- The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function
- (2010) David Warde-Farley et al. NUCLEIC ACIDS RESEARCH
- Finding the missing heritability of complex diseases
- (2009) Teri A. Manolio et al. NATURE
- A Groupwise Association Test for Rare Mutations Using a Weighted Sum Statistic
- (2009) Bo Eskerod Madsen et al. PLoS Genetics
- Methods for Detecting Associations with Rare Variants for Common Diseases: Application to Analysis of Sequence Data
- (2008) Bingshan Li et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Intracellular Transport and Kinesin Superfamily Proteins, KIFs: Structure, Function, and Dynamics
- (2008) Nobutaka Hirokawa et al. PHYSIOLOGICAL REVIEWS
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