Portulaca oleracea L. Extract Alleviated Type 2 Diabetes Via Modulating the Gut Microbiota and Serum Branched‐Chain Amino Acid Metabolism

Role of gut microbiota in type 2 diabetes pathophysiology

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Targeting BCAA Catabolism to Treat Obesity-Associated Insulin Resistance

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The anti-inflammatory potential of Portulaca oleracea L. (purslane) extract by partial suppression on NF-κB and MAPK activation

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Connection Between BMI-Related Plasma Metabolite Profile and Gut Microbiota

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Structural Alteration of Gut Microbiota during the Amelioration of Human Type 2 Diabetes with Hyperlipidemia by Metformin and a Traditional Chinese Herbal Formula: a Multicenter, Randomized, Open Label Clinical Trial

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Diabetes and branched-chain amino acids: What is the link?

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Berberine alleviates insulin resistance by reducing peripheral branched-chain amino acids

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Effect of extraction process on composition, oxidative stability and rheological properties of purslane seed oil

(2017) Sasan Delfan-Hosseini et al.   FOOD CHEMISTRY

Altered amino acid concentrations in NAFLD: Impact of obesity and insulin resistance

(2017) Melania Gaggini et al.   HEPATOLOGY

A review of traditional uses, phytochemistry and pharmacology of Portulaca oleracea L

(2017) Milad Iranshahy et al.   JOURNAL OF ETHNOPHARMACOLOGY

Early-onset and classical forms of type 2 diabetes show impaired expression of genes involved in muscle branched-chain amino acids metabolism

(2017) María Isabel Hernández-Alvarez et al.   Scientific Reports

Cumulative consumption of branched-chain amino acids and incidence of type 2 diabetes

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Human gut microbes impact host serum metabolome and insulin sensitivity

(2016) Helle Krogh Pedersen et al.   NATURE

A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice

(2016) Hubert Plovier et al.   NATURE MEDICINE

Phytochemical composition and bioactive compounds of common purslane ( Portulaca oleracea L.) as affected by crop management practices

(2016) Spyridon Petropoulos et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Akkermansia muciniphila mediates negative effects of IFNγ on glucose metabolism

(2016) Renee L. Greer et al.   Nature Communications

Comparison on hypoglycemic and antioxidant activities of the fresh and dried Portulaca oleracea L. in insulin-resistant HepG2 cells and streptozotocin-induced C57BL/6J diabetic mice

(2015) Jun-fei Gu et al.   JOURNAL OF ETHNOPHARMACOLOGY

The microRNA-200 family regulates pancreatic beta cell survival in type 2 diabetes

(2015) Bengt-Frederik Belgardt et al.   NATURE MEDICINE

Metformin: From Mechanisms of Action to Therapies

(2014) Marc Foretz et al.   Cell Metabolism

Brain Insulin Lowers Circulating BCAA Levels by Inducing Hepatic BCAA Catabolism

(2014) Andrew C. Shin et al.   Cell Metabolism

Portulaca oleracea reduces triglyceridemia, cholesterolemia, and improves lecithin: cholesterol acyltransferase activity in rats fed enriched-cholesterol diet

(2014) Y. Zidan et al.   PHYTOMEDICINE

An increase in theAkkermansiaspp. population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice

(2013) Na-Ri Shin et al.   GUT

Branched chain and aromatic amino acids change acutely following two medical therapies for type 2 diabetes mellitus

(2013) Geoffrey A. Walford et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Human Gut Microbiota Changes Reveal the Progression of Glucose Intolerance

(2013) Xiuying Zhang et al.   PLoS One

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

(2013) A. Everard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Purification and characterization of an antitumor polysaccharide from Portulaca oleracea L.

(2012) Huan Shen et al.   CARBOHYDRATE POLYMERS

Antioxidant activity and phenolic compounds of fractions from Portulaca oleracea L.

(2012) Naciye Erkan   FOOD CHEMISTRY

A metagenome-wide association study of gut microbiota in type 2 diabetes

(2012) Junjie Qin et al.   NATURE

A Protein Tyrosine Phosphatase 1B Activity Inhibitor from the Fruiting Bodies of Ganoderma lucidum (Fr.) Karst and Its Hypoglycemic Potency on Streptozotocin-Induced Type 2 Diabetic Mice

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Effects of Portulaca oleracea L. seeds in treatment of type-2 diabetes mellitus patients as adjunctive and alternative therapy

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Diet-Induced Obesity Is Linked to Marked but Reversible Alterations in the Mouse Distal Gut Microbiome

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