α7 nicotinic acetylcholine receptor agonist GTS-21 attenuates DSS-induced intestinal colitis by improving intestinal mucosal barrier function

25 years of anti-TNF treatment for inflammatory bowel disease: lessons from the past and a look to the future

(2021) Geert R D'Haens et al.   GUT

Acetylcholine ameliorates colitis by promoting IL-10 secretion of monocytic myeloid-derived suppressor cells through the nAChR/ERK pathway

(2021) Wanwei Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nicotinic Acetylcholine Receptor Involvement in Inflammatory Bowel Disease and Interactions with Gut Microbiota

(2021) Lola Rueda Ruzafa et al.   International Journal of Environmental Research and Public Health

Therapeutic Potential of Vagus Nerve Stimulation for Inflammatory Bowel Diseases

(2021) Bruno Bonaz et al.   Frontiers in Neuroscience

Vagus Nerve Stimulation Promotes Epithelial Proliferation and Controls Colon Monocyte Infiltration During DSS-Induced Colitis

(2021) Elisa Meroni et al.   Frontiers in Medicine

The Regulation of Intestinal Mucosal Barrier by Myosin Light Chain Kinase/Rho Kinases

(2020) Younggeon Jin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Non-canonical cholinergic anti-inflammatory pathway in IBD

(2020) Alan de Araujo et al.   Nature Reviews Gastroenterology & Hepatology

Therapeutic ultrasound attenuates DSS-induced colitis through the cholinergic anti-inflammatory pathway

(2019) Natalia Schneider Nunes et al.   EBioMedicine

The role of α7nAChR in controlling the anti-inflammatory/anti-arthritic action of galantamine

(2019) Mennatallah A. Gowayed et al.   BIOCHEMICAL PHARMACOLOGY

Brain orexin improves intestinal barrier function via the vagal cholinergic pathway

(2019) Toshikatsu Okumura et al.   NEUROSCIENCE LETTERS

Listeria Adhesion Protein Induces Intestinal Epithelial Barrier Dysfunction for Bacterial Translocation

(2018) Rishi Drolia et al.   Cell Host & Microbe

Stress burden and neuroendocrine regulation of cytokine production in patients with ulcerative colitis in remission

(2018) Harald Engler et al.   PSYCHONEUROENDOCRINOLOGY

TNF-α Modulation of Intestinal Tight Junction Permeability Is Mediated by NIK/IKK-α Axis Activation of the Canonical NF-κB Pathway

(2016) Rana Al-Sadi et al.   AMERICAN JOURNAL OF PATHOLOGY

Modulatory effects of α7 nAChRs on the immune system and its relevance for CNS disorders

(2016) Hans O. Kalkman et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Expression and Functional Role of α7 Nicotinic Receptor in Human Cytokine-stimulated Natural Killer (NK) Cells

(2016) Samanta R. Zanetti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reduced Mucosa-associated Butyricicoccus Activity in Patients with Ulcerative Colitis Correlates with Aberrant Claudin-1 Expression

(2016) Sarah Devriese et al.   Journal of Crohns & Colitis

1,25-Dihydroxyvitamin D3 preserves intestinal epithelial barrier function from TNF-α induced injury via suppression of NF-kB p65 mediated MLCK-P-MLC signaling pathway

(2015) Shanwen Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mucosal Barrier Depletion and Loss of Bacterial Diversity are Primary Abnormalities in Paediatric Ulcerative Colitis

(2015) Misagh Alipour et al.   Journal of Crohns & Colitis

Activation of the Macrophage α7 Nicotinic Acetylcholine Receptor and Control of Inflammation

(2015) Carlos A. Báez-Pagán et al.   Journal of Neuroimmune Pharmacology

CHRFAM7A, a human-specific and partially duplicated α 7-nicotinic acetylcholine receptor gene with the potential to specify a human-specific inflammatory response to injury

(2014) Todd W. Costantini et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Targeted colonic claudin-2 expression renders resistance to epithelial injury, induces immune suppression and protects from colitis

(2014) R Ahmad et al.   Mucosal Immunology

GTS-21, an α7-nicotinic acetylcholine receptor agonist, modulates Th1 differentiation in CD4+ T cells from patients with rheumatoid arthritis

(2014) SHIYAO WU et al.   Experimental and Therapeutic Medicine

The vagal innervation of the gut and immune homeostasis

(2012) Gianluca Matteoli et al.   GUT

Defective epithelial barrier in chronic rhinosinusitis: The regulation of tight junctions by IFN-γ and IL-4

(2012) Michael B. Soyka et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The vagus nerve and the inflammatory reflex—linking immunity and metabolism

(2012) Valentin A. Pavlov et al.   Nature Reviews Endocrinology

Berberine protects against lipopolysaccharide-induced intestinal injury in mice via alpha 2 adrenoceptor-independent mechanisms

(2011) Hong-mei Li et al.   ACTA PHARMACOLOGICA SINICA

Epithelial inducible nitric oxide synthase causes bacterial translocation by impairment of enterocytic tight junctions via intracellular signals of Rho-associated kinase and protein kinase C zeta*

(2011) Li-Ling Wu et al.   CRITICAL CARE MEDICINE

Interactions Between the Host Innate Immune System and Microbes in Inflammatory Bowel Disease

(2011) Clara Abraham et al.   GASTROENTEROLOGY

Alpha7 nicotinic receptors as novel therapeutic targets for inflammation-based diseases

(2010) Merouane Bencherif et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Berberine attenuates pro-inflammatory cytokine-induced tight junction disruption in an in vitro model of intestinal epithelial cells

(2010) Ning Li et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Claudin-2, a component of the tight junction, forms a paracellular water channel

(2010) R. Rosenthal et al.   JOURNAL OF CELL SCIENCE

Loss of vagal anti-inflammatory effect: in vivo visualization and adoptive transfer

(2009) Caitlin O'Mahony et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

The vagus nerve as a modulator of intestinal inflammation

(2009) e. p. van der zanden et al.   NEUROGASTROENTEROLOGY AND MOTILITY