Bivalent H1 and H3 COBRA Recombinant Hemagglutinin Vaccines Elicit Seroprotective Antibodies against H1N1 and H3N2 Influenza Viruses from 2009 to 2019

Next generation methodology for updating HA vaccines against emerging human seasonal influenza A(H3N2) viruses

(2021) James D. Allen et al.   Scientific Reports

Pre-existing heterosubtypic immunity provides a barrier to airborne transmission of influenza viruses

(2021) Valerie Le Sage et al.   PLoS Pathogens

Diversity in the Circulation of Influenza A(H3N2) Viruses in the Northern Hemisphere in the 2018–19 Season

(2021) Rakefet Pando et al.   Vaccines

Genetic characterisation of the influenza viruses circulating in Bulgaria during the 2019–2020 winter season

(2021) Neli Korsun et al.   VIRUS GENES

Evaluation of Next-Generation H3 Influenza Vaccines in Ferrets Pre-Immune to Historical H3N2 Viruses

(2021) James D. Allen et al.   Frontiers in Immunology

Next Generation of Computationally Optimized Broadly Reactive HA Vaccines Elicited Cross-Reactive Immune Responses and Provided Protection against H1N1 Virus Infection

(2021) Ying Huang et al.   Vaccines

Relative and absolute effectiveness of high-dose and standard-dose influenza vaccine against influenza-related hospitalization among older adults — United States, 2015–2017

(2020) Joshua D Doyle et al.   CLINICAL INFECTIOUS DISEASES

Effects of Influenza Vaccination in the United States during the 2018–2019 Influenza Season

(2020) Jessie R Chung et al.   CLINICAL INFECTIOUS DISEASES

Next-generation influenza vaccines: opportunities and challenges

(2020) Chih-Jen Wei et al.   NATURE REVIEWS DRUG DISCOVERY

Influenza Vaccines Delivered in Early Childhood Could Turn Antigenic Sin into Antigenic Blessings

(2020) Michael Worobey et al.   Cold Spring Harbor Perspectives in Medicine

Original Antigenic Sin: How Original? How Sinful?

(2020) Jonathan W. Yewdell et al.   Cold Spring Harbor Perspectives in Medicine

Antigenic assessment of the H3N2 component of the 2019-2020 Northern Hemisphere influenza vaccine

(2020) Sigrid Gouma et al.   Nature Communications

Tracking progress in universal influenza vaccine development

(2020) Julie Ostrowsky et al.   Current Opinion in Virology

Challenges of Making Effective Influenza Vaccines

(2020) Sigrid Gouma et al.   Annual Review of Virology

Immune Imprinting in the Influenza Ferret Model

(2020) Amanda L. Skarlupka et al.   Vaccines

Imprinting, immunodominance, and other impediments to generating broad influenza immunity

(2020) Matthew Knight et al.   IMMUNOLOGICAL REVIEWS

Original antigenic sin priming of influenza virus hemagglutinin stalk antibodies

(2020) Claudia P. Arevalo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human germinal centres engage memory and naive B cells after influenza vaccination

(2020) Jackson S. Turner et al.   NATURE

Middle-aged individuals may be in a perpetual state of H3N2 influenza virus susceptibility

(2020) Sigrid Gouma et al.   Nature Communications

Next Generation Influenza Vaccines: Looking into the Crystal Ball

(2020) Carlos Alberto Guzmán   Vaccines

High-Yield Expression and Purification of Recombinant Influenza Virus Proteins from Stably-Transfected Mammalian Cell Lines

(2020) Jeffrey W. Ecker et al.   Vaccines

H2 influenza viruses: designing vaccines against future H2 pandemics

(2019) Z. Beau Reneer et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Original Antigenic Sin: How First Exposure Shapes Lifelong Anti–Influenza Virus Immune Responses

(2019) Ali Zhang et al.   JOURNAL OF IMMUNOLOGY

Characterising antibody kinetics from multiple influenza infection and vaccination events in ferrets

(2019) James A. Hay et al.   PLoS Computational Biology

Spread of Antigenically Drifted Influenza A(H3N2) Viruses and Vaccine Effectiveness in the United States During the 2018–2019 Season

(2019) Brendan Flannery et al.   JOURNAL OF INFECTIOUS DISEASES

Update: Influenza Activity — United States and Worldwide, May 19–September 28, 2019, and Composition of the 2020 Southern Hemisphere Influenza Vaccine

(2019) Scott Epperson et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

A Computationally Optimized Broadly Reactive Antigen Subtype–Specific Influenza Vaccine Strategy Elicits Unique Potent Broadly Neutralizing Antibodies against Hemagglutinin

(2019) Giuseppe A. Sautto et al.   JOURNAL OF IMMUNOLOGY

Childhood immune imprinting to influenza A shapes birth year-specific risk during seasonal H1N1 and H3N2 epidemics

(2019) Katelyn M. Gostic et al.   PLoS Pathogens

Estimates of global seasonal influenza-associated respiratory mortality: a modelling study

(2018) A Danielle Iuliano et al.   LANCET

Novel influenza vaccine M2SR protects against drifted H1N1 and H3N2 influenza virus challenge in ferrets with pre-existing immunity

(2018) Yasuko Hatta et al.   VACCINE

Immunodominance hierarchy of influenza subtype-specific neutralizing antibody response as a hurdle to effectiveness of polyvalent vaccine

(2018) Hoyoung Lee et al.   Human Vaccines & Immunotherapeutics

A Synthetic Micro-Consensus DNA Vaccine Generates Comprehensive Influenza A H3N2 Immunity and Protects Mice Against Lethal Challenge by Multiple H3N2 Viruses

(2018) Sarah T.C. Elliott et al.   HUMAN GENE THERAPY

Elicitation of Protective Antibodies against 20 Years of Future H3N2 Cocirculating Influenza Virus Variants in Ferrets Preimmune to Historical H3N2 Influenza Viruses

(2018) James D. Allen et al.   JOURNAL OF VIROLOGY

Cross-Protective Immune Responses Induced by Sequential Influenza Virus Infection and by Sequential Vaccination With Inactivated Influenza Vaccines

(2018) Wei Dong et al.   Frontiers in Immunology

The Doctrine of Original Antigenic Sin: Separating Good From Evil

(2017) Arnold S. Monto et al.   JOURNAL OF INFECTIOUS DISEASES

Elicitation of Protective Antibodies against a Broad Panel of H1N1 Viruses in Ferrets Preimmune to Historical H1N1 Influenza Viruses

(2017) Donald M. Carter et al.   JOURNAL OF VIROLOGY

Computationally Optimized Broadly Reactive Hemagglutinin Elicits Hemagglutination Inhibition Antibodies against a Panel of H3N2 Influenza Virus Cocirculating Variants

(2017) Terianne M. Wong et al.   JOURNAL OF VIROLOGY

ViroSpot microneutralization assay for antigenic characterization of human influenza viruses

(2017) Carel A. van Baalen et al.   VACCINE

Design and Characterization of a Computationally Optimized Broadly Reactive Hemagglutinin Vaccine for H1N1 Influenza Viruses

(2016) Donald M. Carter et al.   JOURNAL OF VIROLOGY

Potent protection against H5N1 and H7N9 influenza via childhood hemagglutinin imprinting

(2016) Katelyn M. Gostic et al.   SCIENCE

Optimization of a Quantitative Micro-neutralization Assay

(2016) Yipu Lin et al.   Jove-Journal of Visualized Experiments

Selection of antigenically advanced variants of seasonal influenza viruses

(2016) Chengjun Li et al.   Nature Microbiology

Sequential Infection in Ferrets with Antigenically Distinct Seasonal H1N1 Influenza Viruses Boosts Hemagglutinin Stalk-Specific Antibodies

(2015) Greg A. Kirchenbaum et al.   JOURNAL OF VIROLOGY

Cocktail of H5N1 COBRA HA vaccines elicit protective antibodies against H5N1 viruses from multiple clades

(2015) Corey J Crevar et al.   Human Vaccines & Immunotherapeutics

Impact of Repeated Vaccination on Vaccine Effectiveness Against Influenza A(H3N2) and B During 8 Seasons

(2014) Huong Q. McLean et al.   CLINICAL INFECTIOUS DISEASES

Eliciting broadly protective antibody responses against influenza

(2014) Greg A Kirchenbaum et al.   CURRENT OPINION IN IMMUNOLOGY

Challenges of selecting seasonal influenza vaccine strains for humans with diverse pre-exposure histories

(2014) Scott E Hensley   Current Opinion in Virology

Impact of Prior Seasonal H3N2 Influenza Vaccination or Infection on Protection and Transmission of Emerging Variants of Influenza A(H3N2)v Virus in Ferrets

(2013) K. V. Houser et al.   JOURNAL OF VIROLOGY

Human H3N2 Influenza Viruses Isolated from 1968 To 2012 Show Varying Preference for Receptor Substructures with No Apparent Consequences for Disease or Spread

(2013) Shelly Gulati et al.   PLoS One

A Computationally Optimized Hemagglutinin Virus-Like Particle Vaccine Elicits Broadly Reactive Antibodies that Protect Nonhuman Primates from H5N1 Infection

(2012) Brendan M. Giles et al.   JOURNAL OF INFECTIOUS DISEASES

Sequential Seasonal H1N1 Influenza Virus Infections Protect Ferrets against Novel 2009 H1N1 Influenza Virus

(2012) Donald M. Carter et al.   JOURNAL OF VIROLOGY

Serologic assays for influenza surveillance, diagnosis and vaccine evaluation

(2011) Jacqueline M Katz et al.   Expert Review of Anti-Infective Therapy

High throughput virus plaque quantitation using a flatbed scanner

(2011) Kate Sullivan et al.   JOURNAL OF VIROLOGICAL METHODS

Vaccine production, distribution, access, and uptake

(2011) Jon Smith et al.   LANCET

A computationally optimized broadly reactive antigen (COBRA) based H5N1 VLP vaccine elicits broadly reactive antibodies in mice and ferrets

(2011) Brendan M. Giles et al.   VACCINE

Impact of prior seasonal influenza vaccination and infection on pandemic A (H1N1) influenza virus replication in ferrets

(2010) A.H. Ellebedy et al.   VACCINE

MDCK-SIAT1 Cells Show Improved Isolation Rates for Recent Human Influenza Viruses Compared to Conventional MDCK Cells

(2008) D. Y. Oh et al.   JOURNAL OF CLINICAL MICROBIOLOGY