Next Generation of Computationally Optimized Broadly Reactive HA Vaccines Elicited Cross-Reactive Immune Responses and Provided Protection against H1N1 Virus Infection

Next generation methodology for updating HA vaccines against emerging human seasonal influenza A(H3N2) viruses

(2021) James D. Allen et al.   Scientific Reports

Relative and absolute effectiveness of high-dose and standard-dose influenza vaccine against influenza-related hospitalization among older adults — United States, 2015–2017

(2020) Joshua D Doyle et al.   CLINICAL INFECTIOUS DISEASES

Inflammation as a Modulator of Host Susceptibility to Pulmonary Influenza, Pneumococcal, and Co-Infections

(2020) Elizabeth R. Aguilera et al.   Frontiers in Immunology

Prevalent Eurasian avian-like H1N1 swine influenza virus with 2009 pandemic viral genes facilitating human infection

(2020) Honglei Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-Yield Expression and Purification of Recombinant Influenza Virus Proteins from Stably-Transfected Mammalian Cell Lines

(2020) Jeffrey W. Ecker et al.   Vaccines

Influenza Vaccine Effectiveness: Defining the H3N2 Problem

(2019) Edward A Belongia et al.   CLINICAL INFECTIOUS DISEASES

N-Linked Glycans and K147 Residue on Hemagglutinin Synergize To Elicit Broadly Reactive H1N1 Influenza Virus Antibodies

(2019) Ying Huang et al.   JOURNAL OF VIROLOGY

Estimates of global seasonal influenza-associated respiratory mortality: a modelling study

(2018) A Danielle Iuliano et al.   LANCET

Elicitation of Protective Antibodies against 20 Years of Future H3N2 Cocirculating Influenza Virus Variants in Ferrets Preimmune to Historical H3N2 Influenza Viruses

(2018) James D. Allen et al.   JOURNAL OF VIROLOGY

Lack of IFNγ signaling attenuates spread of influenza A virus in vivo and leads to reduced pathogenesis

(2018) Marlynne Q. Nicol et al.   VIROLOGY

Infection of Ferrets with Influenza Virus Elicits a Light Chain–Biased Antibody Response against Hemagglutinin

(2017) Greg A. Kirchenbaum et al.   JOURNAL OF IMMUNOLOGY

Elicitation of Protective Antibodies against a Broad Panel of H1N1 Viruses in Ferrets Preimmune to Historical H1N1 Influenza Viruses

(2017) Donald M. Carter et al.   JOURNAL OF VIROLOGY

Computationally Optimized Broadly Reactive Hemagglutinin Elicits Hemagglutination Inhibition Antibodies against a Panel of H3N2 Influenza Virus Cocirculating Variants

(2017) Terianne M. Wong et al.   JOURNAL OF VIROLOGY

Modeling The Economic Burden Of Adult Vaccine-Preventable Diseases In The United States

(2016) Sachiko Ozawa et al.   HEALTH AFFAIRS

The inflammatory response triggered by Influenza virus: a two edged sword

(2016) Luciana P. Tavares et al.   INFLAMMATION RESEARCH

Design and Characterization of a Computationally Optimized Broadly Reactive Hemagglutinin Vaccine for H1N1 Influenza Viruses

(2016) Donald M. Carter et al.   JOURNAL OF VIROLOGY

Variable influenza vaccine effectiveness by subtype: a systematic review and meta-analysis of test-negative design studies

(2016) Edward A Belongia et al.   LANCET INFECTIOUS DISEASES

Epitope specificity plays a critical role in regulating antibody-dependent cell-mediated cytotoxicity against influenza A virus

(2016) Wenqian He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequential Infection in Ferrets with Antigenically Distinct Seasonal H1N1 Influenza Viruses Boosts Hemagglutinin Stalk-Specific Antibodies

(2015) Greg A. Kirchenbaum et al.   JOURNAL OF VIROLOGY

Broadly Neutralizing Anti-Influenza Virus Antibodies: Enhancement of Neutralizing Potency in Polyclonal Mixtures and IgA Backbones

(2015) Wenqian He et al.   JOURNAL OF VIROLOGY

Identification of Amino Acid Substitutions Supporting Antigenic Change of Influenza A(H1N1)pdm09 Viruses

(2015) Björn F. Koel et al.   JOURNAL OF VIROLOGY

Mouse Models of Acute Respiratory Distress Syndrome

(2015) Famke Aeffner et al.   TOXICOLOGIC PATHOLOGY

Cocktail of H5N1 COBRA HA vaccines elicit protective antibodies against H5N1 viruses from multiple clades

(2015) Corey J Crevar et al.   Human Vaccines & Immunotherapeutics

Influenza causes prolonged disruption of the alveolar-capillary barrier in mice unresponsive to mesenchymal stem cell therapy

(2014) Jeffrey E. Gotts et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Eliciting broadly protective antibody responses against influenza

(2014) Greg A Kirchenbaum et al.   CURRENT OPINION IN IMMUNOLOGY

Broadly neutralizing hemagglutinin stalk–specific antibodies require FcγR interactions for protection against influenza virus in vivo

(2014) David J DiLillo et al.   NATURE MEDICINE

EXPOSURE TO SWINE H1 AND H3 AND AVIAN H5 AND H9 INFLUENZA A VIRUSES AMONG FERAL SWINE IN SOUTHERN CHINA, 2009

(2013) Jing Luo et al.   JOURNAL OF WILDLIFE DISEASES

Mechanisms of Hemagglutinin Targeted Influenza Virus Neutralization

(2013) Boerries Brandenburg et al.   PLoS One

Increased transmissibility explains the third wave of infection by the 2009 H1N1 pandemic virus in England

(2013) I. Dorigatti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Computationally Optimized Hemagglutinin Virus-Like Particle Vaccine Elicits Broadly Reactive Antibodies that Protect Nonhuman Primates from H5N1 Infection

(2012) Brendan M. Giles et al.   JOURNAL OF INFECTIOUS DISEASES

Hemagglutinin Stalk-Reactive Antibodies Are Boosted following Sequential Infection with Seasonal and Pandemic H1N1 Influenza Virus in Mice

(2012) F. Krammer et al.   JOURNAL OF VIROLOGY

Sequential Seasonal H1N1 Influenza Virus Infections Protect Ferrets against Novel 2009 H1N1 Influenza Virus

(2012) Donald M. Carter et al.   JOURNAL OF VIROLOGY

Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses

(2012) N. Pica et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antibody Breadth and Protective Efficacy Are Increased by Vaccination with Computationally Optimized Hemagglutinin but Not with Polyvalent Hemagglutinin-Based H5N1 Virus-Like Particle Vaccines

(2011) Brendan M. Giles et al.   Clinical and Vaccine Immunology

High throughput virus plaque quantitation using a flatbed scanner

(2011) Kate Sullivan et al.   JOURNAL OF VIROLOGICAL METHODS

Imaging of Pulmonary Viral Pneumonia

(2011) Tomás Franquet   RADIOLOGY

A computationally optimized broadly reactive antigen (COBRA) based H5N1 VLP vaccine elicits broadly reactive antibodies in mice and ferrets

(2011) Brendan M. Giles et al.   VACCINE

Seasonal influenza and vaccination coverage

(2010) Arnold S. Monto   VACCINE

Influenza vaccines

(2009) A.H. Ellebedy et al.   VACCINE

Pathology of human influenza revisited

(2008) Thijs Kuiken et al.   VACCINE