Zinc and selenium supplementation in COVID-19 prevention and treatment: a systematic review of the experimental studies

A pilot double‐blind safety and feasibility randomized controlled trial of high‐dose intravenous zinc in hospitalized COVID‐19 patients

(2021) Oneel Patel et al.   JOURNAL OF MEDICAL VIROLOGY

Low blood zinc concentrations in patients with poor clinical outcome during SARS-CoV-2 infection: is there a need to supplement with zinc COVID-19 patients?

(2021) Grégory Dubourg et al.   JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION

Effect of High-Dose Zinc and Ascorbic Acid Supplementation vs Usual Care on Symptom Length and Reduction Among Ambulatory Patients With SARS-CoV-2 Infection

(2021) Suma Thomas et al.   JAMA Network Open

Hypozincemia in the early stage of COVID-19 is associated with an increased risk of severe COVID-19

(2021) Julien Fromonot et al.   CLINICAL NUTRITION

Back to basics in COVID‐19: Antigens and antibodies—Completing the puzzle

(2021) Monica Neagu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

A Literature Review on Beneficial Role of Vitamins and Trace Elements: Evidence from Published Clinical Studies

(2021) Sima Taheri et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Does Evidence Exist to Blunt Inflammatory Response by Nutraceutical Supplementation during COVID-19 Pandemic? An Overview of Systematic Reviews of Vitamin D, Vitamin C, Melatonin, and Zinc

(2021) Salvatore Corrao et al.   Nutrients

Decreased Serum Selenium Levels of COVID-19 Patients in Comparison with Healthy Individuals

(2021) Ommolbanin Younesian et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

The correlation between serum selenium, zinc, and COVID-19 severity: an observational study

(2021) Soodeh Razeghi Jahromi et al.   BMC INFECTIOUS DISEASES

A systematic review and dose-response meta-analysis of exposure to environmental selenium and the risk of type 2 diabetes in nonexperimental studies

(2021) Marco Vinceti et al.   ENVIRONMENTAL RESEARCH

SARS-CoV-2 infection incidence during the first and second COVID-19 waves in Italy

(2021) Marco Vinceti et al.   ENVIRONMENTAL RESEARCH

Selenium Deficiency Due to Diet, Pregnancy, Severe Illness, or COVID-19—A Preventable Trigger for Autoimmune Disease

(2021) Lutz Schomburg   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Therapeutic and prognostic role of vitamin D for COVID-19 infection: A systematic review and meta-analysis of 43 observational studies

(2021) Fausto Petrelli et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Potential Prophylactic Treatments for COVID-19

(2021) Noam Ben-Zuk et al.   Viruses-Basel

Nutritional Immunity, Zinc Sufficiency, and COVID-19 Mortality in Socially Similar European Populations

(2021) Samer Singh et al.   Frontiers in Immunology

Lopinavir/Ritonavir and Darunavir/Cobicistat in Hospitalized COVID-19 Patients: Findings From the Multicenter Italian CORIST Study

(2021) Augusto Di Castelnuovo et al.   Frontiers in Medicine

Dramatic Increase in Dietary Supplement Use During Covid-19

(2021) Elif Aysin et al.   Current Developments in Nutrition

Recent advances in management of COVID-19: A review

(2021) Soraya Mouffak et al.   BIOMEDICINE & PHARMACOTHERAPY

Serum trace elements levels and clinical outcomes among Iranian COVID-19 patients

(2021) Ozra Bagher Pour et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Zinc for the prevention or treatment of acute viral respiratory tract infections in adults: a rapid systematic review and meta-analysis of randomised controlled trials

(2021) Jennifer Hunter et al.   BMJ Open

Practical laboratory considerations amidst the COVID-19 outbreak: early experience from Singapore

(2020) Shaun S Tan et al.   JOURNAL OF CLINICAL PATHOLOGY

A systematic review of asymptomatic infections with COVID-19

(2020) Zhiru Gao et al.   JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

(2020) David E. Gordon et al.   NATURE

A role for selenium-dependent GPX1 in SARS-CoV-2 virulence

(2020) Lucia A Seale et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The Minimal Effect of Zinc on the Survival of Hospitalized Patients With COVID-19

(2020) Jasper Seth Yao et al.   CHEST

Immune-boosting role of vitamins D, C, E, zinc, selenium and omega-3 fatty acids: could they help against COVID-19?

(2020) Hira Shakoor et al.   MATURITAS

A Novel Particulate Delivery System Based on Antigen–Zn2+ Coordination Interactions Enhances Stability and Cellular Immune Response of Inactivated Foot and Mouth Disease Virus

(2020) Shuai Li et al.   MOLECULAR PHARMACEUTICS

Selenium Deficiency Is Associated with Mortality Risk from COVID-19

(2020) Arash Moghaddam et al.   Nutrients

COVID-19 outbreak: history, mechanism, transmission, structural studies and therapeutics

(2020) Dhanusha Yesudhas et al.   INFECTION

Zinc sulfate in combination with a zinc ionophore may improve outcomes in hospitalized COVID-19 patients

(2020) Philip M. Carlucci et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Could Vitamins Help in the Fight Against COVID-19?

(2020) Thomas H Jovic et al.   Nutrients

Do Zinc Supplements Enhance the Clinical Efficacy of Hydroxychloroquine?: a Randomized, Multicenter Trial

(2020) Sherief Abd-Elsalam et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

New strategy for COVID-19 vaccination: targeting the receptor-binding domain of the SARS-CoV-2 spike protein

(2020) Junzhi Wang   Cellular & Molecular Immunology

COVID-19 outpatients: early risk-stratified treatment with zinc plus low-dose hydroxychloroquine and azithromycin: a retrospective case series study

(2020) Roland Derwand et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Update on the multi-layered levels of zinc-mediated immune regulation

(2020) Inga Wessels et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Randomised controlled trial for high-dose intravenous zinc as adjunctive therapy in SARS-CoV-2 (COVID-19) positive critically ill patients: trial protocol

(2020) Marlon Perera et al.   BMJ Open

Selenoproteins as regulators of T cell proliferation, differentiation, and metabolism

(2020) Chi Ma et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

RoB 2: a revised tool for assessing risk of bias in randomised trials

(2019) Jonathan A C Sterne et al.   BMJ-British Medical Journal

External quality assessment schemes for inorganic elements in the clinical laboratory: Lessons from the OELM scheme

(2019) Josiane Arnaud et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Randomised controlled trials - the gold standard for effectiveness research

(2018) Eduardo Hariton et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Influence of delayed separation of plasma from whole blood on Cu, I, Mn, Se, and Zn plasma concentrations

(2018) Benoit Chovelon et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Selenium, Selenoproteins, and Immunity

(2018) Joseph Avery et al.   Nutrients

Zinc Signals and Immunity

(2017) Martina Maywald et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Zinc Salts Block Hepatitis E Virus Replication by Inhibiting the Activity of Viral RNA-Dependent RNA Polymerase

(2017) Nidhi Kaushik et al.   JOURNAL OF VIROLOGY

Zinc in Infection and Inflammation

(2017) et al.   Nutrients

They Are What You Eat: Can Nutritional Factors during Gestation and Early Infancy Modulate the Neonatal Immune Response?

(2017) Sarah Prentice   Frontiers in Immunology

Selenium and Human Health: Witnessing a Copernican Revolution?

(2015) Ewa Jablonska et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS

Zinc deficiency enhanced inflammatory response by increasing immune cell activation and inducing IL6 promoter demethylation

(2015) Carmen P. Wong et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Selenium neurotoxicity in humans: Bridging laboratory and epidemiologic studies

(2013) Marco Vinceti et al.   TOXICOLOGY LETTERS

Quantitative data on the magnitude of the systemic inflammatory response and its effect on micronutrient status based on plasma measurements

(2011) Andrew Duncan et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Selenium in Human Health and Disease

(2010) Susan J. Fairweather-Tait et al.   ANTIOXIDANTS & REDOX SIGNALING

Zn2+ Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Zinc Ionophores Block the Replication of These Viruses in Cell Culture

(2010) Aartjan J. W. te Velthuis et al.   PLoS Pathogens