Selenoproteins as regulators of T cell proliferation, differentiation, and metabolism

Selenium and selenoproteins in prostanoid metabolism and immunity

(2020) Fenghua Qian et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Beyond bacterial killing: NADPH oxidase 2 is an immunomodulator

(2020) Silvia Cellone Trevelin et al.   IMMUNOLOGY LETTERS

Selenoprotein T: An Essential Oxidoreductase Serving as a Guardian of Endoplasmic Reticulum Homeostasis

(2020) Hugo Pothion et al.   ANTIOXIDANTS & REDOX SIGNALING

Selenoprotein I is essential for murine embryogenesis

(2020) Joseph C. Avery et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Locations and contributions of the phosphotransferases EPT1 and CEPT1 to the biosynthesis of ethanolamine phospholipids

(2020) Yasuhiro Horibata et al.   JOURNAL OF LIPID RESEARCH

New Directions for Understanding the Codon Redefinition Required for Selenocysteine Incorporation

(2019) Michael T. Howard et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Tolerance to selenoprotein loss differs between human and mouse

(2019) Didac Santesmasses et al.   MOLECULAR BIOLOGY AND EVOLUTION

Endoplasmic reticulum-resident selenoproteins as regulators of calcium signaling and homeostasis

(2018) Matthew W. Pitts et al.   CELL CALCIUM

C-Terminal End-Directed Protein Elimination by CRL2 Ubiquitin Ligases

(2018) Hsiu-Chuan Lin et al.   MOLECULAR CELL

The thioredoxin-1 system is essential for fueling DNA synthesis during T-cell metabolic reprogramming and proliferation

(2018) Jonathan Muri et al.   Nature Communications

Role of Selenof as a Gatekeeper of Secreted Disulfide-Rich Glycoproteins

(2018) Sun Hee Yim et al.   Cell Reports

Metabolic Reprogramming in Modulating T Cell Reactive Oxygen Species Generation and Antioxidant Capacity

(2018) Josephin N. Rashida Gnanaprakasam et al.   Frontiers in Immunology

Role of Selenium Intake for Risk and Development of Hyperthyroidism

(2018) Yue Wang et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Selenium, Selenoproteins, and Immunity

(2018) Joseph Avery et al.   Nutrients

Caught in the cROSsfire: GSH Controls T Cell Metabolic Reprogramming

(2017) Ramon I. Klein Geltink et al.   IMMUNITY

Glutathione Primes T Cell Metabolism for Inflammation

(2017) Tak W. Mak et al.   IMMUNITY

Sex-specific and inter-individual differences in biomarkers of selenium status identified by a calibrated ELISA for selenoprotein P

(2017) Sandra Hybsier et al.   Redox Biology

Why 21? The significance of selenoproteins for human health revealed by inborn errors of metabolism

(2016) Ulrich Schweizer et al.   FASEB JOURNAL

Metabolic pathways in T cell activation and lineage differentiation

(2016) Luís Almeida et al.   SEMINARS IN IMMUNOLOGY

Ferroptosis: Death by Lipid Peroxidation

(2016) Wan Seok Yang et al.   TRENDS IN CELL BIOLOGY

Glutathione peroxidase 1 deficiency attenuates concanavalin A-induced hepatic injury by modulation of T-cell activation

(2016) D H Lee et al.   Cell Death & Disease

Regulation of Selenium Metabolism and Transport

(2015) Raymond F. Burk et al.   Annual Review of Nutrition

T cell lipid peroxidation induces ferroptosis and prevents immunity to infection

(2015) Mai Matsushita et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Effects of selenium on proliferation, interleukin-2 production and selenoprotein mRNA expression of normal and dexamethasone-treated porcine splenocytes

(2015) Tenghan Zhuang et al.   RESEARCH IN VETERINARY SCIENCE

Dietary Selenium in Adjuvant Therapy of Viral and Bacterial Infections

(2015) Holger Steinbrenner et al.   Advances in Nutrition

Regulation of Selenocysteine Content of Human Selenoprotein P by Dietary Selenium and Insertion of Cysteine in Place of Selenocysteine

(2015) Anton A. Turanov et al.   PLoS One

Attenuation of Experimental Colitis in Glutathione Peroxidase 1 and Catalase Double Knockout Mice through Enhancing Regulatory T Cell Function

(2014) Hyung-Ran Kim et al.   PLoS One

Stable expression and function of the inositol 1,4,5-triphosphate receptor requires palmitoylation by a DHHC6/selenoprotein K complex

(2014) Gregory J. Fredericks et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nonsense-mediated decay factors are involved in the regulation of selenoprotein mRNA levels during selenium deficiency

(2014) Ali Seyedali et al.   RNA

Mitochondria Are Required for Antigen-Specific T Cell Activation through Reactive Oxygen Species Signaling

(2013) Laura A. Sena et al.   IMMUNITY

Effect of Micronutrient Supplementation on Disease Progression in Asymptomatic, Antiretroviral-Naive, HIV-Infected Adults in Botswana

(2013) Marianna K. Baum et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Understanding selenoprotein function and regulation through the use of rodent models

(2012) Marina V. Kasaikina et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Decreased STAT5 phosphorylation and GATA-3 expression in NOX2-deficient T cells: Role in T helper development

(2012) Kristen E. Shatynski et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Selenium and human health

(2012) Margaret P Rayman   LANCET

Selenium Promotes T-Cell Response to TCR-Stimulation and ConA, but Not PHA in Primary Porcine Splenocytes

(2012) Fei Ren et al.   PLoS One

T cell Activation Is Driven by an ADP-Dependent Glucokinase Linking Enhanced Glycolysis with Mitochondrial Reactive Oxygen Species Generation

(2012) Marcin M. Kamiński et al.   Cell Reports

The Role of Selenium in Inflammation and Immunity: From Molecular Mechanisms to Therapeutic Opportunities

(2011) Zhi Huang et al.   ANTIOXIDANTS & REDOX SIGNALING

The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation

(2011) Ruoning Wang et al.   IMMUNITY

Selenoprotein K Knockout Mice Exhibit Deficient Calcium Flux in Immune Cells and Impaired Immune Responses

(2011) S. Verma et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets

(2011) R. D. Michalek et al.   JOURNAL OF IMMUNOLOGY

Differentiation of Effector CD4 T Cell Populations

(2010) Jinfang Zhu et al.   Annual Review of Immunology

A Liver-Derived Secretory Protein, Selenoprotein P, Causes Insulin Resistance

(2010) Hirofumi Misu et al.   Cell Metabolism

Generation of effector CD8+ T cells and their conversion to memory T cells

(2010) Weiguo Cui et al.   IMMUNOLOGICAL REVIEWS

Mutations in the selenocysteine insertion sequence–binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans

(2010) Erik Schoenmakers et al.   JOURNAL OF CLINICAL INVESTIGATION

NADPH Oxidase Deficiency Regulates Th Lineage Commitment and Modulates Autoimmunity

(2010) H. M. Tse et al.   JOURNAL OF IMMUNOLOGY

Dietary Selenium Modulates Activation and Differentiation of CD4+ T Cells in Mice through a Mechanism Involving Cellular Free Thiols

(2010) FuKun W. Hoffmann et al.   JOURNAL OF NUTRITION

The human selenoproteome: recent insights into functions and regulation

(2009) M. A. Reeves et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

p47phox, the phagocyte NADPH oxidase/NOX2 organizer: structure, phosphorylation and implication in diseases

(2009) Jamel El-Benna et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Selenoprotein T is a PACAP-regulated gene involved in intracellular Ca2+ mobilization and neuroendocrine secretion

(2008) Luca Grumolato et al.   FASEB JOURNAL

Redox-based regulation of signal transduction: Principles, pitfalls, and promises

(2008) Yvonne M.W. Janssen-Heininger et al.   FREE RADICAL BIOLOGY AND MEDICINE

Selenoproteins Mediate T Cell Immunity through an Antioxidant Mechanism

(2008) Rajeev K. Shrimali et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Trial of the Effect of Micronutrient Supplementation on Treatment Outcome, T Cell Counts, Morbidity, and Mortality in Adults with Pulmonary Tuberculosis

(2008) Eduardo Villamor et al.   JOURNAL OF INFECTIOUS DISEASES

The influence of selenium on immune responses

(2008) Peter R. Hoffmann et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Immunological decision-making: how does the immune system decide to mount a helper T-cell response?

(2007) Gerard E. Kaiko et al.   IMMUNOLOGY