Peanut skin procyanidins ameliorate insulin resistance via modulation of gut microbiota and gut barrier in type 2 diabetic mice

Carob fruit extract-enriched meat, as preventive and curative treatments, improves gut microbiota and colonic barrier integrity in a late-stage T2DM model

(2021) Adrián Macho-González et al.   FOOD RESEARCH INTERNATIONAL

Regulatory effects of hawthorn polyphenols on hyperglycemic, inflammatory, insulin resistance responses, and alleviation of aortic injury in type 2 diabetic rats

(2021) Suwen Liu et al.   FOOD RESEARCH INTERNATIONAL

Antioxidant and Antidiabetic Activity of Proanthocyanidins from Fagopyrum dibotrys

(2021) Xin Li et al.   MOLECULES

Ethanol extract of Sargarsum fusiforme alleviates HFD/STZ-induced hyperglycemia in association with modulation of gut microbiota and intestinal metabolites in type 2 diabetic mice

(2021) Siya Wu et al.   FOOD RESEARCH INTERNATIONAL

Analysis of anti-obesity and anti-diabetic effects of acacia bark-derived proanthocyanidins in type 2 diabetes model KKAy mice

(2021) Mayumi Kashiwada et al.   Journal of Natural Medicines

Comprehensive analysis of the anti-glycation effect of peanut skin extract

(2021) Li Zhao et al.   FOOD CHEMISTRY

Roseburia intestinalis: A Beneficial Gut Organism From the Discoveries in Genus and Species

(2021) Kai Nie et al.   Frontiers in Cellular and Infection Microbiology

Glycan Biosynthesis Ability of Gut Microbiota Increased in Primary Hypertension Patients Taking Antihypertension Medications and Potentially Promoted by Macrophage-Adenosine Monophosphate-Activated Protein Kinase

(2021) Shuai Zheng et al.   Frontiers in Microbiology

Integrated 16S rRNA Sequencing, Metagenomics, and Metabolomics to Characterize Gut Microbial Composition, Function, and Fecal Metabolic Phenotype in Non-obese Type 2 Diabetic Goto-Kakizaki Rats

(2020) Weijun Peng et al.   Frontiers in Microbiology

Role of gut microbiota in type 2 diabetes pathophysiology

(2020) Manoj Gurung et al.   EBioMedicine

Considering gut microbiota in treatment of type 2 diabetes mellitus

(2020) Aneseh Adeshirlarijaney et al.   Gut Microbes

Effect of resveratrol on intestinal tight junction proteins and the gut microbiome in high-fat diet-fed insulin resistant mice

(2020) Kaiting Chen et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

Proanthocyanidins Ameliorated Deficits of Lipid Metabolism in Type 2 Diabetes Mellitus Via Inhibiting Adipogenesis and Improving Mitochondrial Function

(2020) Fangfang Tie et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Polyphenols isolated from lychee seed inhibit Alzheimer's disease-associated Tau through improving insulin resistance via the IRS-1/PI3K/Akt/GSK-3β pathway

(2020) Rui Xiong et al.   JOURNAL OF ETHNOPHARMACOLOGY

Effect of Caesalpinia bonduc Polyphenol Extract on Alloxan-Induced Diabetic Rats in Attenuating Hyperglycemia by Upregulating Insulin Secretion and Inhibiting JNK Signaling Pathway

(2020) Asra Iftikhar et al.   Oxidative Medicine and Cellular Longevity

Anti-diabetic effects of Bifidobacterium animalis 01 through improving hepatic insulin sensitivity in type 2 diabetic rat model

(2020) Jinlan Zhang et al.   Journal of Functional Foods

Peanut skin extract ameliorates the symptoms of type 2 diabetes mellitus in mice by alleviating inflammation and maintaining gut microbiota homeostasis

(2020) Lan Xiang et al.   Aging-US

Cocoa diet modulates gut microbiota composition and improves intestinal health in Zucker diabetic rats

(2020) David Álvarez-Cilleros et al.   FOOD RESEARCH INTERNATIONAL

Gut microbiota in human metabolic health and disease

(2020) Yong Fan et al.   NATURE REVIEWS MICROBIOLOGY

Parabacteroides distasonis Alleviates Obesity and Metabolic Dysfunctions via Production of Succinate and Secondary Bile Acids

(2019) Kai Wang et al.   Cell Reports

Peanut skin phenolic extract attenuates hyperglycemic responses in vivo and in vitro

(2019) Lindsey M. Christman et al.   PLoS One

A critical review of the relationship between dietary components, the gut microbe Akkermansia muciniphila, and human health

(2019) Muthukumaran Jayachandran et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Anti-diabetic activity of PUFAs-rich extracts of Chlorella pyrenoidosa and Spirulina platensis in rats

(2019) Xu-zhi Wan et al.   FOOD AND CHEMICAL TOXICOLOGY

An exopolysaccharide from Lactobacillus plantarum H31 in pickled cabbage inhibits pancreas α-amylase and regulating metabolic markers in HepG2 cells by AMPK/PI3K/Akt pathway

(2019) Zhenghua Huang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Beneficial Effects of Dietary Polyphenols on High-Fat Diet-Induced Obesity Linking with Modulation of Gut Microbiota

(2019) Jianhui Liu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Beyond Host Defense: Emerging Functions of the Immune System in Regulating Complex Tissue Physiology

(2018) Lucille C. Rankin et al.   CELL

Restructuring of the Gut Microbiome by Intermittent Fasting Prevents Retinopathy and Prolongs Survival in db/db Mice

(2018) Eleni Beli et al.   DIABETES

Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection

(2018) Christoph A. Thaiss et al.   SCIENCE

Dietary supplementation of A-type procyanidins from litchi pericarp improves glucose homeostasis by modulating mTOR signaling and oxidative stress in diabetic ICR mice

(2018) Xiaopeng Li et al.   Journal of Functional Foods

Granny Smith apple procyanidin extract upregulates tight junction protein expression and modulates oxidative stress and inflammation in lipopolysaccharide-induced Caco-2 cells

(2018) H. Wu et al.   Food & Function

IL-6 signalling pathways and the development of type 2 diabetes

(2018) Mohamad Akbari et al.   INFLAMMOPHARMACOLOGY

(-)-Epicatechin protects the intestinal barrier from high fat diet-induced permeabilization: Implications for steatosis and insulin resistance

(2018) Eleonora Cremonini et al.   Redox Biology

High-molecular-weight cocoa procyanidins possess enhanced insulin-enhancing and insulin mimetic activities in human primary skeletal muscle cells compared to smaller procyanidins

(2017) Suzanne M. Bowser et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug

(2017) Hao Wu et al.   NATURE MEDICINE

More Flavor for Flavonoid-Based Interventions?

(2017) Nadeem O. Kaakoush et al.   TRENDS IN MOLECULAR MEDICINE

IL-6, TNF-α, and IL-10 levels/polymorphisms and their association with type 2 diabetes mellitus and obesity in Brazilian individuals

(2017) Kathryna Fontana Rodrigues et al.   Archives of Endocrinology Metabolism

Original Research: Polyphenols extracted from grape powder induce lipogenesis and glucose uptake during differentiation of murine preadipocytes

(2016) Sheida Torabi et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Oral Administration of Apple Procyanidins Ameliorates Insulin Resistance via Suppression of Pro-Inflammatory Cytokine Expression in Liver of Diabetic ob/ob Mice

(2016) Kasane Ogura et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Effect of mulberry leaf (Folium Mori) on insulin resistance via IRS-1/PI3K/Glut-4 signalling pathway in type 2 diabetes mellitus rats

(2016) Shengyu Cai et al.   PHARMACEUTICAL BIOLOGY

Impact of the gut microbiota on inflammation, obesity, and metabolic disease

(2016) Claire L. Boulangé et al.   Genome Medicine

Bioavailability and Hypolipidemic Effects of Peanut Skin Polyphenols

(2015) Rishipal R. Bansode et al.   JOURNAL OF MEDICINAL FOOD

Anti-inflammatory effects of grape seed procyanidin B2 on a diabetic pancreas

(2015) Wenbin Yin et al.   Food & Function

Procyanidins and Their Healthy Protective Effects Against Type 2 Diabetes

(2014) Noemi Gonzalez-Abuin et al.   CURRENT MEDICINAL CHEMISTRY

A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increasedAkkermansiaspp. population in the gut microbiota of mice

(2014) Fernando F Anhê et al.   GUT

Mechanisms for Insulin Resistance: Common Threads and Missing Links

(2012) Varman T. Samuel et al.   CELL

Bioavailability of Intact Proanthocyanidins in the Rat Colon after Ingestion of Grape Seed Extract

(2012) Ying Yng Choy et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A metagenome-wide association study of gut microbiota in type 2 diabetes

(2012) Junjie Qin et al.   NATURE

Dietary Grape-Seed Procyanidins Decreased Postweaning Diarrhea by Modulating Intestinal Permeability and Suppressing Oxidative Stress in Rats

(2011) Peixia Song et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Prebiotic evaluation of cocoa-derived flavanols in healthy humans by using a randomized, controlled, double-blind, crossover intervention study

(2010) Xenofon Tzounis et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Gut Microbiota in Human Adults with Type 2 Diabetes Differs from Non-Diabetic Adults

(2010) Nadja Larsen et al.   PLoS One

Insights into the metabolism and microbial biotransformation of dietary flavan-3-ols and the bioactivity of their metabolites

(2010) Maria Monagas et al.   Food & Function