Catalytic Asymmetric Construction of Axially and Centrally Chiral Heterobiaryls by Minisci Reaction

Organocatalytic Atroposelective Synthesis of N−N Axially Chiral Indoles and Pyrroles by De Novo Ring Formation

(2022) Ke‐Wei Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Radical Reactions Using Chiral Catalysts

(2022) Shovan Mondal et al.   CHEMICAL REVIEWS

Recent advances in Minisci-type reactions and applications in organic synthesis

(2021) Wengui Wang et al.   CURRENT ORGANIC CHEMISTRY

Synthesis of Axially Chiral 2,2′-Bisphosphobiarenes via a Nickel-Catalyzed Asymmetric Ullmann Coupling: General Access to Privileged Chiral Ligands without Optical Resolution

(2021) Ziqing Zuo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Single Electron Transfer-Induced Redox Processes Involving N-(Acyloxy)phthalimides

(2021) Sushanta Kumar Parida et al.   ACS Catalysis

Enantioselective Radical Carbocyanation of 1,3-Dienes via Photocatalytic Generation of Allylcopper Complexes

(2021) Fu-Dong Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Synthesis of Axially Chiral Benzothiophene/Benzofuran‐Fused Biaryls by N‐Heterocyclic Carbene Catalyzed Arene Formation

(2021) Chun‐Lin Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Synthesis of Silicon‐Stereogenic Dihydrodibenzosilines: Silicon Central‐to‐Axial Chirality Relay

(2021) Yonghong Guo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantiodivergent Kinetic Resolution of 1,1′‐Biaryl‐2,2′‐Diols and Amino Alcohols by Dipeptide‐Phosphonium Salt Catalysis Inspired by the Atherton–Todd Reaction

(2021) Siqiang Fang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Acridinium Salts and Cyanoarenes as Powerful Photocatalysts: Opportunities in Organic Synthesis

(2021) Anis Tlili et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Advances in Catalytic Asymmetric Construction of Atropisomers

(2021) Jun Kee Cheng et al.   CHEMICAL REVIEWS

Hydrogen Atom Transfer-Driven Enantioselective Minisci Reaction of Amides

(2021) Rupert S. J. Proctor et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Atropo‐Enantioselective Oxidation‐Enabled Iridium(III)‐Catalyzed C−H Arylations with Aryl Boronic Esters

(2021) Łukasz Woźniak et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Photoinduced Copper‐Catalyzed Asymmetric Three‐Component Coupling of 1,3‐Dienes: An Alternative to Kharasch–Sosnovsky Reaction

(2021) Peng‐Zi Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Twofold C−H Activation‐Based Enantio‐ and Diastereoselective C−H Arylation Using Diarylacetylenes as Rare Arylating Reagents

(2021) Panjie Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Photoinduced Copper-Catalyzed Asymmetric C–O Cross-Coupling

(2021) Jun Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photochemical Deracemization of Primary Allene Amides by Triplet Energy Transfer: A Combined Synthetic and Theoretical Study

(2021) Manuel Plaza et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Synthesis of Axially Chiral Biaryls by Diels–Alder/Retro-Diels–Alder Reaction of 2-Pyrones with Alkynes

(2021) Meng-Meng Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rational Design of Axially Chiral Styrene‐Based Organocatalysts and Their Application in Catalytic Asymmetric (2+4) Cyclizations

(2021) Si‐Jia Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Axially Chiral Biaryl-2-amines by PdII -Catalyzed Free-Amine-Directed Atroposelective C−H Olefination

(2020) Bei-Bei Zhan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ir-Catalyzed Atroposelective Desymmetrization of Heterobiaryls: Hydroarylation of Vinyl Ethers and Bicycloalkenes

(2020) Antonio Romero-Arenas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Palladaelectro‐Catalyzed C–H Activations by Transient Directing Groups: Expedient Access to Helicenes

(2020) Uttam Dhawa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Construction of Axially Chiral Indole‐Based Frameworks: An Emerging Area

(2020) Tian-Zhen Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

Mechanism and Origins of Enantio- and Regioselectivities in Catalytic Asymmetric Minisci-Type Addition to Heteroarenes

(2020) Aili Feng et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Ni-Catalyzed Electrochemical Synthesis of Biaryl Atropisomers

(2020) Hui Qiu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Computational and Experimental Investigation of the Origin of Selectivity in the Chiral Phosphoric Acid Catalyzed Enantioselective Minisci Reaction

(2020) Kristaps Ermanis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photocatalytic decarboxylative alkylations mediated by triphenylphosphine and sodium iodide

(2019) Ming-Chen Fu et al.   SCIENCE

Enantioselective Synthesis of Biaryl Atropisomers via Pd-Catalyzed C-H Olefination using Chiral Spiro Phosphoric Acid Ligands

(2019) Jun Luo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Advances in Minisci-Type Reactions

(2019) Rupert S. J. Proctor et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Kinetic Resolution by Enantioselective Aromatization: Conversion of Racemic Intermediates of the Barton-Zard Reaction into Enantioenriched 3-Arylpyrroles

(2019) Sheng-Cai Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Carbon-Carbon Bond Cleavage for Biaryl Atropisomers Synthesis

(2019) Ruixian Deng et al.   Chem

Rhodium-Catalyzed Atroposelective C–H Arylation: Efficient Synthesis of Axially Chiral Heterobiaryls

(2019) Qiang Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Strategy for Synthesizing Axially Chiral Naphthyl-Indoles: Catalytic Asymmetric Addition Reactions of Racemic Substrates

(2019) Fei Jiang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diastereo- and Atroposelective Synthesis of Bridged Biaryls Bearing an Eight-Membered Lactone through an Organocatalytic Cascade

(2019) Shenci Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Predictive Multivariate Linear Regression Analysis Guides Successful Catalytic Enantioselective Minisci Reactions of Diazines

(2019) Jolene P. Reid et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Construction of Axially Chiral Compounds via Asymmetric Organocatalysis

(2018) Yong-Bin Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Remote Central-to-Axial Chirality Conversion: Direct Atroposelective Ester to Biaryl Transformation

(2018) Achim Link et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Scalable, Stereocontrolled Formal Syntheses of (+)-Isoschizandrin and (+)-Steganone: Development and Applications of Palladium(II)-Catalyzed Atroposelective C−H Alkynylation

(2018) Gang Liao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dynamic Kinetic Resolution of Heterobiaryl Ketones by Zinc-Catalyzed Asymmetric Hydrosilylation

(2018) Valentín Hornillos et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent encounters with atropisomerism in drug discovery

(2018) Peter W. Glunz   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design and Synthesis of Chiral oxa-Spirocyclic Ligands for Ir-Catalyzed Direct Asymmetric Reduction of Bringmann’s Lactones with Molecular H2

(2018) Gen-Qiang Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic enantioselective Minisci-type addition to heteroarenes

(2018) Rupert S. J. Proctor et al.   SCIENCE

Enhanced Reactivity by Torsional Strain of Cyclic Diaryliodonium in Cu-Catalyzed Enantioselective Ring-Opening Reaction

(2018) Kun Zhao et al.   Chem

N -(Acyloxy)phthalimides as Redox-Active Esters in Cross-Coupling Reactions

(2018) Sandip Murarka   ADVANCED SYNTHESIS & CATALYSIS

Dynamic Kinetic Asymmetric Heck Reaction for the Simultaneous Generation of Central and Axial Chirality

(2018) José A. Carmona et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Enantioselective Addition of α-Aminoalkyl Radicals to Isoquinolines

(2018) Xiangyuan Liu et al.   ORGANIC LETTERS

Design and Catalytic Asymmetric Construction of Axially Chiral 3,3′-Bisindole Skeletons

(2018) Chun Ma et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic deracemization of chiral allenes by sensitized excitation with visible light

(2018) Alena Hölzl-Hobmeier et al.   NATURE

Organocatalytic asymmetric arylation of indoles enabled by azo groups

(2017) Liang-Wen Qi et al.   Nature Chemistry

Enantiodivergent Atroposelective Synthesis of Chiral Biaryls by Asymmetric Transfer Hydrogenation: Chiral Phosphoric Acid Catalyzed Dynamic Kinetic Resolution

(2016) Keiji Mori et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design and Enantioselective Construction of Axially Chiral Naphthyl-Indole Skeletons

(2016) Hong-Hao Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of IAN-type N,N-Ligands via Dynamic Kinetic Asymmetric Buchwald–Hartwig Amination

(2016) Pedro Ramírez-López et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Kinetic Resolution of Axially Chiral 5- or 8-Substituted Quinolines via Asymmetric Transfer Hydrogenation

(2016) Jie Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dynamic Kinetic Resolution of Biaryl Lactones via a Chiral Bifunctional Amine Thiourea-Catalyzed Highly Atropo-enantioselective Transesterification

(2016) Chenguang Yu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and Application of Chiral Spiro Cp Ligands in Rhodium-Catalyzed Asymmetric Oxidative Coupling of Biaryl Compounds with Alkenes

(2016) Jun Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Radicals: Reactive Intermediates with Translational Potential

(2016) Ming Yan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Addressing the Challenges in Suzuki–Miyaura Cross-Couplings by Ligand Design

(2016) Wenjun Tang et al.   SYNLETT

Donor–Acceptor Fluorophores for Visible-Light-Promoted Organic Synthesis: Photoredox/Ni Dual Catalytic C(sp3)–C(sp2) Cross-Coupling

(2016) Jian Luo et al.   ACS Catalysis

Chiral Monophosphorus Ligands for Asymmetric Catalytic Reactions

(2016) Wenzhen Fu et al.   ACS Catalysis

Combining Organocatalysis with Central-to-Axial Chirality Conversion: Atroposelective Hantzsch-Type Synthesis of 4-Arylpyridines

(2015) Ophélie Quinonero et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aromatic Amide-Derived Non-Biaryl Atropisomers as Highly Efficient Ligands in Silver-Catalyzed Asymmetric Cycloaddition Reactions

(2015) Xing-Feng Bai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nonbiaryl and Heterobiaryl Atropisomers: Molecular Templates with Promise for Atropselective Chemical Transformations

(2015) Elango Kumarasamy et al.   CHEMICAL REVIEWS

Enantioselective and Enantiospecific Transition-Metal-Catalyzed Cross-Coupling Reactions of Organometallic Reagents To Construct C–C Bonds

(2015) Alan H. Cherney et al.   CHEMICAL REVIEWS

Recent advances and new concepts for the synthesis of axially stereoenriched biaryls

(2015) J. Wencel-Delord et al.   CHEMICAL SOCIETY REVIEWS

Atroposelective Synthesis of Axially Chiral Biaryldiols via Organocatalytic Arylation of 2-Naphthols

(2015) Ye-Hui Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Atroposelective Aldol Condensation: Synthesis of Axially Chiral Biaryls by Arene Formation

(2014) Achim Link et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Efficient Syntheses of Korupensamines A, B and Michellamine B by Asymmetric Suzuki-Miyaura Coupling Reactions

(2013) Guangqing Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Atropoisomeric (P,N) Ligands for the Highly Enantioselective Pd-Catalyzed Intramolecular Asymmetric α-Arylation of α-Branched Aldehydes

(2012) Pradeep Nareddy et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Enantioselective Chlorination of β-Keto Esters and Subsequent SN2 Displacement of Tertiary Chlorides: A Flexible Method for the Construction of Quaternary Stereogenic Centers

(2012) Kazutaka Shibatomi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Revealing Atropisomer Axial Chirality in Drug Discovery

(2011) Steven R. LaPlante et al.   ChemMedChem

Assessing Atropisomer Axial Chirality in Drug Discovery and Development

(2011) Steven R. LaPlante et al.   JOURNAL OF MEDICINAL CHEMISTRY

Minisci reactions: Versatile CH-functionalizations for medicinal chemists

(2011) Matthew A. J. Duncton   MedChemComm

Atroposelective Total Synthesis of Axially Chiral Biaryl Natural Products

(2010) Gerhard Bringmann et al.   CHEMICAL REVIEWS

The Challenge of Atropisomerism in Drug Discovery

(2009) Jonathan Clayden et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION