Radiotherapy Reduces N-Oxides for Prodrug Activation in Tumors

Reversibly Photoswitching Upconversion Nanoparticles for Super‐sensitive Photoacoustic Molecular Imaging

(2022) Jianghong Rao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synergistic checkpoint-blockade and radiotherapy–radiodynamic therapy via an immunomodulatory nanoscale metal–organic framework

(2022) Kaiyuan Ni et al.   Nature Biomedical Engineering

U.S. FDA Approved Drugs from 2015–June 2020: A Perspective

(2021) Priyadeep Bhutani et al.   JOURNAL OF MEDICINAL CHEMISTRY

Desilylation Induced by Metal Fluoride Nanocrystals Enables Cleavage Chemistry In Vivo

(2021) Dongban Duan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Unleashing the Power of Bond Cleavage Chemistry in Living Systems

(2021) Jie Wang et al.   ACS Central Science

Enhanced tumour penetration and prolonged circulation in blood of polyzwitterion–drug conjugates with cell-membrane affinity

(2021) Siqin Chen et al.   Nature Biomedical Engineering

A Cationic Micelle as In Vivo Catalyst for Tumor‐Localized Cleavage Chemistry

(2021) Chunhong Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Photosensitive Ru(II) Complexes as Inhibitors of the Major Human Drug Metabolizing Enzyme CYP3A4

(2021) Nicholas Toupin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Switching on prodrugs using radiotherapy

(2021) Jin Geng et al.   Nature Chemistry

A bioorthogonal system reveals antitumour immune function of pyroptosis

(2020) Qinyang Wang et al.   NATURE

External Radiation–Induced Local Hydroxylation Enables Remote Release of Functional Molecules in Tumors

(2020) Qunfeng Fu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Artificial intelligence in radiation oncology

(2020) Elizabeth Huynh et al.   Nature Reviews Clinical Oncology

Radiotherapy toxicity

(2019) Dirk De Ruysscher et al.   Nature Reviews Disease Primers

Unexpected Hydrated Electron Source for Preparative Visible-Light Driven Photoredox Catalysis

(2019) Christoph Kerzig et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Precision Cancer Theranostic Platform by In Situ Polymerization in Perylene Diimide-Hybridized Hollow Mesoporous Organosilica Nanoparticles

(2019) Zhen Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Macrocyclization of a Class of Camptothecin Analogues into Tubular Supramolecular Polymers

(2019) Hao Su et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The expanding role of prodrugs in contemporary drug design and development

(2018) Jarkko Rautio et al.   NATURE REVIEWS DRUG DISCOVERY

Catch and Release Photosensitizers: Combining Dual-Action Ruthenium Complexes with Protease Inactivation for Targeting Invasive Cancers

(2018) Karan Arora et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A bioreducible N-oxide-based probe for photoacoustic imaging of hypoxia

(2017) Hailey J. Knox et al.   Nature Communications

Click and Release: A Chemical Strategy toward Developing Gasotransmitter Prodrugs by Using an Intramolecular Diels-Alder Reaction

(2016) Xingyue Ji et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Bioorthogonal Reaction ofN-Oxide and Boron Reagents

(2015) Justin Kim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals

(2014) Edon Vitaku et al.   JOURNAL OF MEDICINAL CHEMISTRY

Rattle-Structured Multifunctional Nanotheranostics for Synergetic Chemo-/Radiotherapy and Simultaneous Magnetic/Luminescent Dual-Mode Imaging

(2013) Wenpei Fan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Water Radiolysis: Influence of Oxide Surfaces on H2 Production under Ionizing Radiation

(2011) Sophie Le Caër   Water

The importance of radiation chemistry to radiation and free radical biology (The 2008 Silvanus Thompson Memorial Lecture)

(2009) P WARDMAN   BRITISH JOURNAL OF RADIOLOGY

Spin Trapping of Radicals Other Than the•OH Radical upon Reduction of the Anticancer Agent Tirapazamine by Cytochrome P450Reductase

(2009) Sujata S. Shinde et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY