Overview on the complexity of androgen receptor-targeted therapy for prostate cancer
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Overview on the complexity of androgen receptor-targeted therapy for prostate cancer
Authors
Keywords
Prostate cancer, Intracellular signaling, Apoptosis
Journal
Cancer Cell International
Volume 15, Issue 1, Pages 7
Publisher
Springer Nature
Online
2015-02-03
DOI
10.1186/s12935-014-0153-1
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Castration Induces Up-Regulation of Intratumoral Androgen Biosynthesis and Androgen Receptor Expression in an Orthotopic VCaP Human Prostate Cancer Xenograft Model
- (2014) Matias Knuuttila et al. AMERICAN JOURNAL OF PATHOLOGY
- Histone H4 Lys 20 methyltransferase SET8 promotes androgen receptor-mediated transcription activation in prostate cancer
- (2014) Lushuai Yao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Antiproliferative activity of novel imidazopyridine derivatives on castration-resistant human prostate cancer cells
- (2014) Sakthivel Muniyan et al. CANCER LETTERS
- Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer
- (2014) Maria Thadani-Mulero et al. CANCER RESEARCH
- Rapid Induction of Androgen Receptor Splice Variants by Androgen Deprivation in Prostate Cancer
- (2014) Z. Yu et al. CLINICAL CANCER RESEARCH
- Niclosamide Inhibits Androgen Receptor Variants Expression and Overcomes Enzalutamide Resistance in Castration-Resistant Prostate Cancer
- (2014) C. Liu et al. CLINICAL CANCER RESEARCH
- Phase II Study of Single-Agent Orteronel (TAK-700) in Patients with Nonmetastatic Castration-Resistant Prostate Cancer and Rising Prostate-Specific Antigen
- (2014) M. Hussain et al. CLINICAL CANCER RESEARCH
- Androgen receptor and its splice variant, AR-V7, differentially regulate FOXA1 sensitive genes in LNCaP prostate cancer cells
- (2014) William C. Krause et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Selectively Targeting the DNA-binding Domain of the Androgen Receptor as a Prospective Therapy for Prostate Cancer
- (2014) Kush Dalal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A New Avenue toward Androgen Receptor Pan-antagonists: C2 Sterically Hindered Substitution of Hydroxy-propanamides
- (2014) Andrea Guerrini et al. JOURNAL OF MEDICINAL CHEMISTRY
- Discovery of 1H-Indole-2-carboxamides as Novel Inhibitors of the Androgen Receptor Binding Function 3 (BF3)
- (2014) Fuqiang Ban et al. JOURNAL OF MEDICINAL CHEMISTRY
- A hormone-dependent feedback-loop controls androgen receptor levels by limiting MID1, a novel translation enhancer and promoter of oncogenic signaling
- (2014) Andrea Köhler et al. Molecular Cancer
- Nuclear Mobility and Activity of FOXA1 with Androgen Receptor Are Regulated by SUMOylation
- (2014) Päivi Sutinen et al. MOLECULAR ENDOCRINOLOGY
- SUMOylation modulates the transcriptional activity of androgen receptor in a target gene and pathway selective manner
- (2014) Päivi Sutinen et al. NUCLEIC ACIDS RESEARCH
- Targeting autophagy overcomes Enzalutamide resistance in castration-resistant prostate cancer cells and improves therapeutic response in a xenograft model
- (2014) H G Nguyen et al. ONCOGENE
- Rosemary (Rosmarinus officinalis) Extract Modulates CHOP/GADD153 to Promote Androgen Receptor Degradation and Decreases Xenograft Tumor Growth
- (2014) Sakina M. Petiwala et al. PLoS One
- Stilbene Induced Inhibition of Androgen Receptor Dimerization: Implications for AR and ARΔLBD-Signalling in Human Prostate Cancer Cells
- (2014) Wolfgang Streicher et al. PLoS One
- Chem-seq permits identification of genomic targets of drugs against androgen receptor regulation selected by functional phenotypic screens
- (2014) C. Jin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Overexpression of HepaCAM inhibits cell viability and motility through suppressing nucleus translocation of androgen receptor and ERK signaling in prostate cancer
- (2014) Xuedong Song et al. PROSTATE
- Determinants of Gli2 co-activation of wildtype and naturally truncated androgen receptors
- (2014) Na Li et al. PROSTATE
- Clinical activity of enzalutamide in Docetaxel-naïve and Docetaxel-pretreated patients with metastatic castration-resistant prostate cancer
- (2014) Rosa Nadal et al. PROSTATE
- Walnut polyphenol metabolites, urolithins A and B, inhibit the expression of the prostate-specific antigen and the androgen receptor in prostate cancer cells
- (2014) Claudia Sánchez-González et al. Food & Function
- Destruction of Full-Length Androgen Receptor by Wild-Type SPOP, but Not Prostate-Cancer-Associated Mutants
- (2014) Jian An et al. Cell Reports
- Glucocorticoid Receptor Confers Resistance to Antiandrogens by Bypassing Androgen Receptor Blockade
- (2013) Vivek K. Arora et al. CELL
- Combination Therapy with a Second-Generation Androgen Receptor Antagonist and a Metastasis Vaccine Improves Survival in a Spontaneous Prostate Cancer Model
- (2013) A. Ardiani et al. CLINICAL CANCER RESEARCH
- Methylselenol prodrug enhances MDV3100 efficacy for treatment of castration-resistant prostate cancer
- (2013) Yang Zhan et al. INTERNATIONAL JOURNAL OF CANCER
- Androgen Receptor Splice Variant AR3 Promotes Prostate Cancer via Modulating Expression of Autocrine/Paracrine Factors
- (2013) Feng Sun et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Advances in Androgen Receptor Targeted Therapy for Prostate Cancer
- (2013) Alia Ahmed et al. JOURNAL OF CELLULAR PHYSIOLOGY
- AZD3514: A Small Molecule That Modulates Androgen Receptor Signaling and Function In Vitro and In Vivo
- (2013) S. A. Loddick et al. MOLECULAR CANCER THERAPEUTICS
- A Naturally Derived Small Molecule Disrupts Ligand-Dependent and Ligand-Independent Androgen Receptor Signaling in Human Prostate Cancer Cells
- (2013) K. S. Amin et al. MOLECULAR CANCER THERAPEUTICS
- Spongian Diterpenoids Inhibit Androgen Receptor Activity
- (2013) Y. C. Yang et al. MOLECULAR CANCER THERAPEUTICS
- NF- B2/p52 Induces Resistance to Enzalutamide in Prostate Cancer: Role of Androgen Receptor and Its Variants
- (2013) N. Nadiminty et al. MOLECULAR CANCER THERAPEUTICS
- Mechanisms of the androgen receptor splicing in prostate cancer cells
- (2013) L L Liu et al. ONCOGENE
- Betulinic Acid Selectively Increases Protein Degradation and Enhances Prostate Cancer-Specific Apoptosis: Possible Role for Inhibition of Deubiquitinase Activity
- (2013) Teresita Reiner et al. PLoS One
- Differential Effects of Genistein on Prostate Cancer Cells Depend on Mutational Status of the Androgen Receptor
- (2013) Abeer M. Mahmoud et al. PLoS One
- Androgen Receptor Activity Is Affected by Both Nuclear Matrix Localization and the Phosphorylation Status of the Heterogeneous Nuclear Ribonucleoprotein K in Anti-Androgen-Treated LNCaP Cells
- (2013) Paola Barboro et al. PLoS One
- TALEN-engineered AR gene rearrangements reveal endocrine uncoupling of androgen receptor in prostate cancer
- (2013) M. D. Nyquist et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Skp2 regulates androgen receptor through ubiquitin-mediated degradation independent of Akt/mTOR pathways in prostate cancer
- (2013) Bo Li et al. PROSTATE
- Anti-androgen receptor ASC-J9 versus anti-androgens MDV3100 (Enzalutamide) or Casodex (Bicalutamide) leads to opposite effects on prostate cancer metastasis via differential modulation of macrophage infiltration and STAT3-CCL2 signaling
- (2013) T-H Lin et al. Cell Death & Disease
- A Clinically Relevant Androgen Receptor Mutation Confers Resistance to Second-Generation Antiandrogens Enzalutamide and ARN-509
- (2013) J. D. Joseph et al. Cancer Discovery
- 2-(4-Chlorophenyl)-2-oxoethyl 4-benzamidobenzoate derivatives, a novel class of SENP1 inhibitors: Virtual screening, synthesis and biological evaluation
- (2012) Yingyi Chen et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Thein VivoRole of Androgen Receptor SUMOylation as Revealed by Androgen Insensitivity Syndrome and Prostate Cancer Mutations Targeting the Proline/Glycine Residues of Synergy Control Motifs
- (2012) Sarmistha Mukherjee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dynamic SUMOylation Is Linked to the Activity Cycles of Androgen Receptor in the Cell Nucleus
- (2012) M. Rytinki et al. MOLECULAR AND CELLULAR BIOLOGY
- Vav3 Enhances Androgen Receptor Splice Variant Activity and Is Critical for Castration-Resistant Prostate Cancer Growth and Survival
- (2012) Stephanie O. Peacock et al. MOLECULAR ENDOCRINOLOGY
- Prostaglandin 15d-PGJ2Inhibits Androgen Receptor Signaling in Prostate Cancer Cells
- (2012) Sanna Kaikkonen et al. MOLECULAR ENDOCRINOLOGY
- Triptolide Inhibits the Proliferation of Prostate Cancer Cells and Down-Regulates SUMO-Specific Protease 1 Expression
- (2012) Weiwei Huang et al. PLoS One
- Modeling Truncated AR Expression in a Natural Androgen Responsive Environment and Identification of RHOB as a Direct Transcriptional Target
- (2012) Hui-Chi Tsai et al. PLoS One
- The activity of the androgen receptor variant AR-V7 is regulated by FOXO1 in a PTEN-PI3K-AKT-dependent way
- (2012) Sanjay N. Mediwala et al. PROSTATE
- Regulation of androgen receptor expression byZ-isochaihulactone mediated by the JNK signaling pathway and might be related to cytotoxicity in prostate cancer
- (2012) Po-Yen Liu et al. PROSTATE
- Design, synthesis, and biological evaluation of benzodiazepine-based SUMO-specific protease 1 inhibitors
- (2011) Zhitao Qiao et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Novel Membrane-associated Androgen Receptor Splice Variant Potentiates Proliferative and Survival Responses in Prostate Cancer Cells
- (2011) Xi Yang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor
- (2010) P. A. Watson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started