Monitoring Blood-Brain Barrier Integrity Following Amyloid-β Immunotherapy Using Gadolinium-Enhanced MRI in a PDAPP Mouse Model

Blood-Brain Barrier Permeability and Gadolinium

(2016) Axel Montagne et al.   JAMA Neurology

Blood-Brain Barrier Breakdown in the Aging Human Hippocampus

(2015) Axel Montagne et al.   NEURON

Blood–brain barrier impairment in dementia: Current and future in vivo assessments

(2015) Harm J. van de Haar et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease

(2014) Stephen Salloway et al.   NEW ENGLAND JOURNAL OF MEDICINE

Vascular alterations in PDAPP mice after anti-Aβ immunotherapy: Implications for amyloid-related imaging abnormalities

(2013) Wagner Zago et al.   Alzheimers & Dementia

Blood–Brain Barrier Dysfunction as a Cause and Consequence of Alzheimer's Disease

(2013) Michelle A Erickson et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Development, maintenance and disruption of the blood-brain barrier

(2013) Birgit Obermeier et al.   NATURE MEDICINE

Longitudinal assessment of blood–brain barrier leakage during epileptogenesis in rats. A quantitative MRI study

(2013) E.A. van Vliet et al.   NEUROBIOLOGY OF DISEASE

Blood-Brain Barrier Permeability of Normal Appearing White Matter in Relapsing-Remitting Multiple Sclerosis

(2013) Henrik Lund et al.   PLoS One

Passive anti-amyloid immunotherapy in Alzheimer's disease: What are the most promising targets?

(2013) Jens Moreth et al.   Immunity & Ageing

Neutralization of Soluble, Synaptotoxic Amyloid   Species by Antibodies Is Epitope Specific

(2012) W. Zago et al.   JOURNAL OF NEUROSCIENCE

Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis

(2012) Reisa Sperling et al.   LANCET NEUROLOGY

Use of Contrast Media in Neuroimaging

(2012) Marco Essig et al.   Magnetic Resonance Imaging Clinics of North America

Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: Recommendations from the Alzheimer’s Association Research Roundtable Workgroup

(2011) Reisa A. Sperling et al.   Alzheimers & Dementia

Mechanism of Amyloid Removal in Patients With Alzheimer Disease Treated With Gantenerumab

(2011) Susanne Ostrowitzki   ARCHIVES OF NEUROLOGY

Noninvasive Magnetic Resonance Imaging Detection of Cerebral Amyloid Angiopathy-Related Microvascular Alterations Using Superparamagnetic Iron Oxide Particles in APP Transgenic Mouse Models of Alzheimer's Disease: Application to Passive A  Immunotherapy

(2011) N. Beckmann et al.   JOURNAL OF NEUROSCIENCE

The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics

(2011) Eric Karran et al.   NATURE REVIEWS DRUG DISCOVERY

Blood–Brain Barrier Permeability Abnormalities in Vascular Cognitive Impairment

(2011) Saeid Taheri et al.   STROKE

A Single Ascending Dose Study of Bapineuzumab in Patients With Alzheimer Disease

(2010) Ronald S. Black et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Low-density lipoprotein receptor-related protein-1: a serial clearance homeostatic mechanism controlling Alzheimer’s amyloid β-peptide elimination from the brain

(2010) Berislav V. Zlokovic et al.   JOURNAL OF NEUROCHEMISTRY

Immunotherapy, Vascular Pathology, and Microhemorrhages in Transgenic Mice

(2009) Donna Wilcock et al.   CNS & Neurological Disorders-Drug Targets

Cerebral microbleeds: a guide to detection and interpretation

(2009) Steven M Greenberg et al.   LANCET NEUROLOGY

Evolution of the neocortex: a perspective from developmental biology

(2009) Pasko Rakic   NATURE REVIEWS NEUROSCIENCE

A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease

(2009) S. Salloway et al.   NEUROLOGY

Consequence of Aβ immunization on the vasculature of human Alzheimer's disease brain

(2008) D. Boche et al.   BRAIN

Immunotherapy Reduces Vascular Amyloid-  in PDAPP Mice

(2008) S. Schroeter et al.   JOURNAL OF NEUROSCIENCE