Hepatic stellate cells in physiology and pathology

Heterogeneity of hepatic stellate cells in a mouse model of non‐alcoholic steatohepatitis (NASH)

(2021) Sara Brin Rosenthal et al.   HEPATOLOGY

Hepatic Stellate Cell Activation and Inactivation in NASH-Fibrosis—Roles as Putative Treatment Targets?

(2021) Alexandra Zisser et al.   Biomedicines

Collagen proportionate area correlates with histological stage and predicts clinical events in primary sclerosing cholangitis

(2021) Francesca Saffioti et al.   LIVER INTERNATIONAL

Single-nucleus RNA-seq2 reveals functional crosstalk between liver zonation and ploidy

(2021) M. L. Richter et al.   Nature Communications

Heterogeneity of Hepatic Stellate Cells in Fibrogenesis of the Liver: Insights from Single-Cell Transcriptomic Analysis in Liver Injury

(2021) Wenjun Zhang et al.   Cells

p70 ribosomal protein S6 kinase is a checkpoint of human hepatic stellate cell activation and liver fibrosis in mice

(2021) Florian P. Reiter et al.   Cellular and Molecular Gastroenterology and Hepatology

Association Between Fibrosis Stage and Outcomes of Patients with Non-Alcoholic Fatty Liver Disease: a Systematic Review and Meta-Analysis

(2020) Rod S. Taylor et al.   GASTROENTEROLOGY

Identification of Lineage-specific Transcription Factors That Prevent Activation of Hepatic Stellate Cells and Promote Fibrosis Resolution

(2020) Xiao Liu et al.   GASTROENTEROLOGY

Single-Cell Transcriptome Analysis of Mouse Liver Cell-Specific Tropism and Transcriptional Dysregulation Following Intravenous Administration of AAVrh.10 Vectors

(2020) Detu Zhu et al.   HUMAN GENE THERAPY

Retinoids in health and disease: A role for hepatic stellate cells in affecting retinoid levels

(2020) Maya W. Haaker et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Peroxisome proliferator-activated receptor γ inhibits hepatic stellate cell activation regulated by miR-942 in chronic hepatitis B liver fibrosis

(2020) Le Tao et al.   LIFE SCIENCES

Single nuclei RNA sequencing assessment of the hepatic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin

(2020) Rance Nault et al.   Cellular and Molecular Gastroenterology and Hepatology

Single nucleus transcriptomics data integration recapitulates the major cell types in human liver

(2020) Klev Diamanti et al.   HEPATOLOGY RESEARCH

A single cell atlas of the human liver tumor microenvironment

(2020) Hassan Massalha et al.   Molecular Systems Biology

The Power of Plasticity—Metabolic Regulation of Hepatic Stellate Cells

(2020) Parth Trivedi et al.   Cell Metabolism

Hepatic stellate cell activation: A source for bioactive lipids

(2019) Igor O. Shmarakov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Response to Pioglitazone in Patients With Nonalcoholic Steatohepatitis With vs Without Type 2 Diabetes

(2018) Fernando Bril et al.   Clinical Gastroenterology and Hepatology

Single cell RNA sequencing of human liver reveals distinct intrahepatic macrophage populations

(2018) Sonya A. MacParland et al.   Nature Communications

Targeting the mitochondrial pyruvate carrier attenuates fibrosis in a mouse model of nonalcoholic steatohepatitis

(2017) Kyle S. McCommis et al.   HEPATOLOGY

Fibrosis stage but not NASH predicts mortality and time to development of severe liver disease in biopsy-proven NAFLD

(2017) Hannes Hagström et al.   JOURNAL OF HEPATOLOGY

Histological parameters and alcohol abstinence determine long-term prognosis in patients with alcoholic liver disease

(2017) Carolin Lackner et al.   JOURNAL OF HEPATOLOGY

Adipose triglyceride lipase is involved in the mobilization of triglyceride and retinoid stores of hepatic stellate cells

(2015) Ulrike Taschler et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Vitamin A and retinol-binding protein deficiency among chronic liver disease patients

(2015) Gabriela Villaça Chaves et al.   NUTRITION

PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells

(2014) Carlo Pirazzi et al.   HUMAN MOLECULAR GENETICS

High prevalence of vitamin A deficiency and vitamin D deficiency in patients evaluated for liver transplantation

(2013) Mukund Venu et al.   LIVER TRANSPLANTATION

Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology

(2013) Ingmar Mederacke et al.   Nature Communications

Autophagy Releases Lipid That Promotes Fibrogenesis by Activated Hepatic Stellate Cells in Mice and in Human Tissues

(2012) Virginia Hernández–Gea et al.   GASTROENTEROLOGY

Hedgehog Controls Hepatic Stellate Cell Fate by Regulating Metabolism

(2012) Yuping Chen et al.   GASTROENTEROLOGY

A novel murine model to deplete hepatic stellate cells uncovers their role in amplifying liver damage in mice

(2012) Juan E. Puche et al.   HEPATOLOGY

NK cells from HCV-infected patients effectively induce apoptosis of activated primary human hepatic stellate cells in a TRAIL-, FasL- and NKG2D-dependent manner

(2012) Andreas Glässner et al.   LABORATORY INVESTIGATION

Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis

(2012) T. Kisseleva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Depletion of activated hepatic stellate cell correlates with severe liver damage and abnormal liver regeneration in acetaminophen-induced liver injury

(2011) K. Shen et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Meta-analysis: pioglitazone improves liver histology and fibrosis in patients with non-alcoholic steatohepatitis

(2011) E. Boettcher et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Noninvasive Tests for Fibrosis and Liver Stiffness Predict 5-Year Outcomes of Patients With Chronic Hepatitis C

(2011) Julien Vergniol et al.   GASTROENTEROLOGY

Stimulating healthy tissue regeneration by targeting the 5-HT2B receptor in chronic liver disease

(2011) Mohammad R Ebrahimkhani et al.   NATURE MEDICINE

Septum transversum-derived mesothelium gives rise to hepatic stellate cells and perivascular mesenchymal cells in developing mouse liver

(2010) Kinji Asahina et al.   HEPATOLOGY

Hepatic stellate cells’ involvement in progenitor-mediated liver regeneration

(2010) Dana G Pintilie et al.   LABORATORY INVESTIGATION

Serum retinol binding protein as an indicator of vitamin A status in cirrhotic patients with night blindness

(2009) Khalid Mahmood et al.   Saudi Journal of Gastroenterology

Expression of carboxylesterase and lipase genes in rat liver cell-types

(2008) Tommaso Mello et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development

(2008) Kinji Asahina et al.   HEPATOLOGY

Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver

(2008) Scott L. Friedman   PHYSIOLOGICAL REVIEWS

Fate-Mapping Evidence That Hepatic Stellate Cells Are Epithelial Progenitors in Adult Mouse Livers

(2008) Liu Yang et al.   STEM CELLS