Intrinsically Disordered N-terminal Domain (NTD) of p53 Interacts with Mitochondrial PTP Regulator Cyclophilin D

p53 Is Potentially Regulated by Cyclophilin D in the Triple-Proline Loop of the DNA Binding Domain

(2021) Jacques Kumutima et al.   BIOCHEMISTRY

Residual Structures and Transient Long-Range Interactions of p53 Transactivation Domain: Assessment of Explicit Solvent Protein Force Fields

(2019) Xiaorong Liu et al.   Journal of Chemical Theory and Computation

Long-range regulation of p53 DNA binding by its intrinsically disordered N-terminal transactivation domain

(2018) Alexander S. Krois et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HyRes: a coarse-grained model for multi-scale enhanced sampling of disordered protein conformations

(2017) Xiaorong Liu et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

A Novel In Vitro CypD-Mediated p53 Aggregation Assay Suggests a Model for Mitochondrial Permeability Transition by Chaperone Systems

(2016) Ivan Lebedev et al.   JOURNAL OF MOLECULAR BIOLOGY

Cyclophilin D counteracts P53-mediated growth arrest and promotes Ras tumorigenesis

(2016) A Bigi et al.   ONCOGENE

TP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functions

(2016) Nitin H Shirole et al.   eLife

Structural mechanisms of cyclophilin D-dependent control of the mitochondrial permeability transition pore

(2015) Manuel Gutiérrez-Aguilar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

ROS-p53-cyclophilin-D signaling mediates salinomycin-induced glioma cell necrosis

(2015) Li-sen Qin et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Modelling the molecular mechanism of protein–protein interactions and their inhibition: CypD–p53 case study

(2015) S. M. Fayaz et al.   MOLECULAR DIVERSITY

Structural insights into the transcription-independent apoptotic pathway of p53

(2014) Seung-Wook Chi   BMB Reports

P53 Dependent Mitochondrial Permeability Transition Pore Opening Is Required for Dexamethasone-Induced Death of Osteoblasts

(2014) Yun-fang Zhen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

DAPK1-p53 Interaction Converges Necrotic and Apoptotic Pathways of Ischemic Neuronal Death

(2014) L. Pei et al.   JOURNAL OF NEUROSCIENCE

A Conserved Mechanism for Binding of p53 DNA-Binding Domain and Anti-Apoptotic Bcl-2 Family Proteins

(2014) Dong-Hwa Lee et al.   MOLECULES AND CELLS

p53  is a transcriptionally inactive p53 isoform able to reprogram cells toward a metastatic-like state

(2014) S. Senturk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Using chemical shift perturbation to characterise ligand binding

(2013) Mike P. Williamson   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

p53 Opens the Mitochondrial Permeability Transition Pore to Trigger Necrosis

(2012) Angelina V. Vaseva et al.   CELL

Structure of the p53 Transactivation Domain in Complex with the Nuclear Receptor Coactivator Binding Domain of CREB Binding Protein

(2010) Chul Won Lee et al.   BIOCHEMISTRY

The missing Zinc: p53 misfolding and cancer

(2010) Stewart N. Loh   Metallomics

Single-Molecule characterization of oligomerization kinetics and equilibria of the tumor suppressor p53

(2010) S. Rajagopalan et al.   NUCLEIC ACIDS RESEARCH

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

CHARMM: The biomolecular simulation program

(2009) B. R. Brooks et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY