TP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functions
Published 2016 View Full Article
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Title
TP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functions
Authors
Keywords
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Journal
eLife
Volume 5, Issue -, Pages -
Publisher
eLife Sciences Organisation, Ltd.
Online
2016-10-19
DOI
10.7554/elife.17929
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- (2014) Patricia A.J. Muller et al. CANCER CELL
- Molecular mechanisms of epithelial–mesenchymal transition
- (2014) Samy Lamouille et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- p53 is a transcriptionally inactive p53 isoform able to reprogram cells toward a metastatic-like state
- (2014) S. Senturk et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2014) Grzegorz J. Korpanty et al. Frontiers in Oncology
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- (2012) W. A. Freed-Pastor et al. GENES & DEVELOPMENT
- The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.
- (2012) Ethan Cerami et al. Cancer Discovery
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- (2009) Valentina Giorgio et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Mutant p53 Gain-of-Function in Cancer
- (2009) M. Oren et al. Cold Spring Harbor Perspectives in Biology
- TP53 Mutations in Human Cancers: Origins, Consequences, and Clinical Use
- (2009) M. Olivier et al. Cold Spring Harbor Perspectives in Biology
- A meta-analysis of nonsense mutations causing human genetic disease
- (2008) Matthew Mort et al. HUMAN MUTATION
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