LncRNA-PACERR induces pro-tumour macrophages via interacting with miR-671-3p and m6A-reader IGF2BP2 in pancreatic ductal adenocarcinoma

The CTCF/LncRNA‐PACERR complex recruits E1A binding protein p300 to induce pro‐tumour macrophages in pancreatic ductal adenocarcinoma via directly regulating PTGS2 expression

(2022) Yihao Liu et al.   Clinical and Translational Medicine

Cancer Statistics, 2021

(2021) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Author Correction: Gene regulation by long non-coding RNAs and its biological functions

(2021) Luisa Statello et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

PIWIL1 interacting RNA piR-017061 inhibits pancreatic cancer growth via regulating EFNA5

(2021) Jing Xie et al.   Human Cell

CLK1/SRSF5 pathway induces aberrant exon skipping of METTL14 and Cyclin L2 and promotes growth and metastasis of pancreatic cancer

(2021) Shi Chen et al.   Journal of Hematology & Oncology

Oncogene APOL1 promotes proliferation and inhibits apoptosis via activating NOTCH1 signaling pathway in pancreatic cancer

(2021) Jiewei Lin et al.   Cell Death & Disease

Potentiated lung adenocarcinoma (LUAD) cell growth, migration and invasion by lncRNA DARS-AS1 via miR-188-5p/ KLF12 axis

(2021) Yangyang Liu et al.   Aging-US

EIF4A3-induced circARHGAP29 promotes aerobic glycolysis in docetaxel-resistant prostate cancer through IGF2BP2/c-Myc/LDHA signaling

(2021) Xingkang Jiang et al.   CANCER RESEARCH

The Roles and Mechanisms of lncRNAs in Liver Fibrosis

(2020) Zhi He et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions

(2020) Elena Grossi et al.   Nature Communications

m6A Modification in Coding and Non-coding RNAs: Roles and Therapeutic Implications in Cancer

(2020) Huilin Huang et al.   CANCER CELL

The role of long noncoding RNAs in hepatocellular carcinoma

(2020) Zhao Huang et al.   Molecular Cancer

The tumour microenvironment in pancreatic cancer — clinical challenges and opportunities

(2020) Won Jin Ho et al.   Nature Reviews Clinical Oncology

Immunotherapy for pancreatic cancer: A 2020 update

(2020) Dimitrios Schizas et al.   CANCER TREATMENT REVIEWS

Macrophage M1/M2 polarization

(2020) Chen Yunna et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Pancreatic cancer

(2020) Jonathan D Mizrahi et al.   LANCET

CRISPR-assisted detection of RNA–protein interactions in living cells

(2020) Wenkai Yi et al.   NATURE METHODS

Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2

(2020) Chunqing Wang et al.   Nature Communications

Engineering Macrophages for Cancer Immunotherapy and Drug Delivery

(2020) Yuqiong Xia et al.   ADVANCED MATERIALS

Challenges and Opportunities for Pancreatic Cancer Immunotherapy

(2020) Adham S. Bear et al.   CANCER CELL

Exosomal miR-141 promotes tumor angiogenesis via KLF12 in small cell lung cancer

(2020) Shuangshuang Mao et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

lncRNA-PACER upregulates COX-2 and PGE2 through the NF-κB pathway to promote the proliferation and invasion of colorectal-cancer cells

(2020) Peng Sun et al.   Gastroenterology Report

MicroRNA-137 reduces stemness features of pancreatic cancer cells by targeting KLF12

(2019) Zhiwei He et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Cellular functions of long noncoding RNAs

(2019) Run-Wen Yao et al.   NATURE CELL BIOLOGY

Single-cell RNA-seq highlights intra-tumoral heterogeneity and malignant progression in pancreatic ductal adenocarcinoma

(2019) Junya Peng et al.   CELL RESEARCH

METTL3 facilitates tumor progression via an m6A-IGF2BP2-dependent mechanism in colorectal carcinoma

(2019) Ting Li et al.   Molecular Cancer

Long Noncoding RNA (lncRNA)-Mediated Competing Endogenous RNA Networks Provide Novel Potential Biomarkers and Therapeutic Targets for Colorectal Cancer

(2019) Liye Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

An allosteric PGAM1 inhibitor effectively suppresses pancreatic ductal adenocarcinoma

(2019) Chen-Lei Wen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Landscape of Noncoding RNA in Prostate Cancer

(2019) Junjie T. Hua et al.   TRENDS IN GENETICS

IGF2BP2 regulates DANCR by serving as an N6-methyladenosine reader

(2019) Xiaoge Hu et al.   CELL DEATH AND DIFFERENTIATION

Up-regulation of IGF2BP2 by multiple mechanisms in pancreatic cancer promotes cancer proliferation by activating the PI3K/Akt signaling pathway

(2019) Xiaodong Xu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

LncRNA LINRIS stabilizes IGF2BP2 and promotes the aerobic glycolysis in colorectal cancer

(2019) Yun Wang et al.   Molecular Cancer

LncRNA MT1JP functions as a ceRNA in regulating FBXW7 through competitively binding to miR-92a-3p in gastric cancer

(2018) Gang Zhang et al.   Molecular Cancer

Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation

(2018) Huilin Huang et al.   NATURE CELL BIOLOGY

Structural basis of IMP3 RRM12 recognition of RNA

(2018) Min Jia et al.   RNA

Dysregulation of Krüppel-like factor 12 in the development of endometrial cancer

(2018) Ling Ding et al.   GYNECOLOGIC ONCOLOGY

Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression

(2017) Yu Zhu et al.   IMMUNITY

How do lncRNAs regulate transcription?

(2017) Yicheng Long et al.   Science Advances

IRX3 Promotes the Browning of White Adipocytes and Its Rare Variants are Associated with Human Obesity Risk

(2017) Yaoyu Zou et al.   EBioMedicine

Tumour-suppression function of KLF12 through regulation of anoikis

(2015) N Godin-Heymann et al.   ONCOGENE

P50-associated COX-2 extragenic RNA (PACER) overexpression promotes proliferation and metastasis of osteosarcoma cells by activating COX-2 gene

(2015) Ming Qian et al.   TUMOR BIOLOGY

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Overexpression of receptor tyrosine kinase Axl promotes tumor cell invasion and survival in pancreatic ductal adenocarcinoma

(2010) Xianzhou Song et al.   CANCER

The Axl receptor tyrosine kinase confers an adverse prognostic influence in pancreatic cancer and represents a new therapeutic target

(2010) Jan-Bart M. Koorstra et al.   CANCER BIOLOGY & THERAPY