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Centromere Protein U (CENPU) enhances angiogenesis in triple-negative breast cancer by inhibiting ubiquitin–proteasomal degradation of COX-2

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The Role of Non-coding RNAs in Oncology

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Long noncoding RNA GAS5 inhibits progression of colorectal cancer by interacting with and triggering YAP phosphorylation and degradation and is negatively regulated by the m6A reader YTHDF3

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(2019) Henry Lee-Six et al.   NATURE

GRK2 Mediated Abnormal Transduction of PGE2-EP4-cAMP-CREB Signaling Induces the Imbalance of Macrophages Polarization in Collagen-Induced Arthritis Mice

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LncRNA HOTAIR is a Prognostic Biomarker for the Proliferation and Chemoresistance of Colorectal Cancer via MiR-203a-3p-Mediated Wnt/ß-Catenin Signaling Pathway

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MEG3 Activated by Vitamin D Inhibits Colorectal Cancer Cells Proliferation and Migration via Regulating Clusterin

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Long noncoding RNA myocardial infarction-associated transcript regulated the pancreatic stellate cell activation to promote the fibrosis process of chronic pancreatitis

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Expression of long non-coding RNA CCHE1 in colorectal carcinoma: correlations with clinicopathological features and ERK/COX-2 pathway

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YAP transcriptionally regulates COX-2 expression and GCCSysm-4 (G-4), a dual YAP/COX-2 inhibitor, overcomes drug resistance in colorectal cancer

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Mining the Stiffness-Sensitive Transcriptome in Human Vascular Smooth Muscle Cells Identifies Long Noncoding RNA Stiffness Regulators

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Long Noncoding RNAs in Cancer Pathways

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Prostaglandin E2 Promotes Colorectal Cancer Stem Cell Expansion and Metastasis in Mice

(2015) Dingzhi Wang et al.   GASTROENTEROLOGY

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(2015) Maite Huarte   NATURE MEDICINE

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P50-associated COX-2 extragenic RNA (PACER) overexpression promotes proliferation and metastasis of osteosarcoma cells by activating COX-2 gene

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(2015) John S Mattick et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

STIM1 overexpression promotes colorectal cancer progression, cell motility and COX-2 expression

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Functional expression cloning identifies COX-2 as a suppressor of antigen-specific cancer immunity

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p50-associated COX-2 extragenic RNA (PACER) activates COX-2 gene expression by occluding repressive NF-κB complexes

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Epigenetic deregulation of the COX pathway in cancer

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(2012) B. Akhtar-Zaidi et al.   SCIENCE

MicroRNA-451 Is Involved in the Self-renewal, Tumorigenicity, and Chemoresistance of Colorectal Cancer Stem Cells

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