Integration of electrochemical interface and cell-free synthetic biology for biosensing

PAM-less conditional DNA substrates leverage trans-cleavage of CRISPR-Cas12a for versatile live-cell biosensing

(2022) Siyu Chen et al.   Chemical Science

Coupling of proteolysis-triggered transcription and CRISPR-Cas12a for ultrasensitive protease detection

(2021) Min Yang et al.   Science China-Chemistry

Synthetic biology in the clinic: engineering vaccines, diagnostics, and therapeutics

(2021) Xiao Tan et al.   CELL

Rapid SARS-CoV-2 Spike Protein Detection by Carbon Nanotube-Based Near-Infrared Nanosensors

(2021) Rebecca L. Pinals et al.   NANO LETTERS

A glucose meter interface for point-of-care gene circuit-based diagnostics

(2021) Evan Amalfitano et al.   Nature Communications

Universal and Programmable Rolling Circle Amplification-CRISPR/Cas12a-Mediated Immobilization-Free Electrochemical Biosensor

(2021) Min Qing et al.   ANALYTICAL CHEMISTRY

CRISPR-powered electrochemical microfluidic multiplexed biosensor for target amplification-free miRNA diagnostics

(2021) Richard Bruch et al.   BIOSENSORS & BIOELECTRONICS

Electrochemical Strategy for Low-Cost Viral Detection

(2021) Marjon Zamani et al.   ACS Central Science

Duplex-Specific Nuclease-Assisted CRISPR-Cas12a Strategy for MicroRNA Detection Using a Personal Glucose Meter

(2021) Shaohua Gong et al.   ANALYTICAL CHEMISTRY

Wearable materials with embedded synthetic biology sensors for biomolecule detection

(2021) Peter Q. Nguyen et al.   NATURE BIOTECHNOLOGY

Liposome-mediated detection of SARS-CoV-2 RNA-positive extracellular vesicles in plasma

(2021) Bo Ning et al.   Nature Nanotechnology

CRISPR-based diagnostics

(2021) Michael M. Kaminski et al.   Nature Biomedical Engineering

Amplified and label-free electrochemical detection of a protease biomarker by integrating proteolysis-triggered transcription

(2021) Kai Shi et al.   BIOSENSORS & BIOELECTRONICS

Protocell arrays for simultaneous detection of diverse analytes

(2021) Yan Zhang et al.   Nature Communications

Point-of-Care Analyte Quantification and Digital Readout via Lysate-Based Cell-Free Biosensors Interfaced with Personal Glucose Monitors

(2021) Yan Zhang et al.   ACS Synthetic Biology

Electrochemical biosensors based on nucleic acid aptamers

(2020) Anabel Villalonga et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

A systematic approach to quantitative Western blot analysis

(2020) Lakshmi Pillai-Kastoori et al.   ANALYTICAL BIOCHEMISTRY

Sensitive detection of a bacterial pathogen using allosteric probe-initiated catalysis and CRISPR-Cas13a amplification reaction

(2020) Jinjin Shen et al.   Nature Communications

Aptamer-Functionalized DNA Nanostructures for Biological Applications

(2020) Xiaoyi Fu et al.   Topics in Current Chemistry

Surpassing the detection limit and accuracy of the electrochemical DNA sensor through the application of CRISPR Cas systems

(2020) Wei Xu et al.   BIOSENSORS & BIOELECTRONICS

DNA framework-engineered electrochemical biosensors

(2020) Fan Li et al.   Science China-Life Sciences

Emerging strategies to enhance the sensitivity of competitive ELISA for detection of chemical contaminants in food samples

(2020) Ying Xiong et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

CRISPR/Cas13a Powered Portable Electrochemiluminescence Chip for Ultrasensitive and Specific MiRNA Detection

(2020) Ting Zhou et al.   Advanced Science

A CRISPR-based assay for the detection of opportunistic infections post-transplantation and for the monitoring of transplant rejection

(2020) Michael M. Kaminski et al.   Nature Biomedical Engineering

Biological Materials: The Next Frontier for Cell-Free Synthetic Biology

(2020) Richard J. R. Kelwick et al.   Frontiers in Bioengineering and Biotechnology

Cell-free biosensors for rapid detection of water contaminants

(2020) Jaeyoung K. Jung et al.   NATURE BIOTECHNOLOGY

An Integrated Multi‐Function Heterogeneous Biochemical Circuit for High‐Resolution Electrochemistry‐Based Genetic Analysis

(2020) Yifan Dai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The second decade of synthetic biology: 2010–2020

(2020) Fankang Meng et al.   Nature Communications

Proteolysis-Responsive Rolling Circle Transcription Assay Enabling Femtomolar Sensitivity Detection of a Target Protease Biomarker

(2020) Xingyu Luo et al.   ANALYTICAL CHEMISTRY

Nontargeted Detection Methods for Food Safety and Integrity

(2019) Bing Shao et al.   Annual Review of Food Science and Technology

Advances in Surface Plasmon Resonance Imaging and Microscopy and Their Biological Applications

(2019) Markéta Bocková et al.   Annual Review of Analytical Chemistry

Interfacing a Personal Glucose Meter with Cell-Free Protein Synthesis for Rapid Analysis of Amino Acids

(2019) Yeon-Jae Jang et al.   ANALYTICAL CHEMISTRY

Recent Advances on Electrochemical Biosensing Strategies toward Universal Point of Care Systems

(2019) Yifan Dai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

CRISPR/Cas Multiplexed Biosensing: A Challenge or an Insurmountable Obstacle?

(2019) Yi Li et al.   TRENDS IN BIOTECHNOLOGY

Ultrasensitive Detection of Salmonella and Listeria monocytogenes by Small-Molecule Chemiluminescence Probes

(2019) Michal Roth-Konforti et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fast gas chromatography-mass spectrometry: A review of the last decade

(2019) Mariosimone Zoccali et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Exploring the Trans-Cleavage Activity of CRISPR-Cas12a (cpf1) for the Development of a Universal Electrochemical Biosensor

(2019) Yifan Dai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A multiplexed, electrochemical interface for gene-circuit-based sensors

(2019) Peivand Sadat Mousavi et al.   Nature Chemistry

A CRISPR-Cas12a-derived biosensing platform for the highly sensitive detection of diverse small molecules

(2019) Mindong Liang et al.   Nature Communications

CRISPR-Cas System for RNA Detection and Imaging

(2019) Siyu Chen et al.   CHEMICAL RESEARCH IN CHINESE UNIVERSITIES

Functional DNA Regulated CRISPR-Cas12a Sensors for Point-of-Care Diagnostics of Non-Nucleic-Acid Targets

(2019) Ying Xiong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Innovative engineering and sensing strategies for aptamer-based small-molecule detection

(2019) Obtin Alkhamis et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Electrochemical sensor and biosensor platforms based on advanced nanomaterials for biological and biomedical applications

(2018) Govindhan Maduraiveeran et al.   BIOSENSORS & BIOELECTRONICS

CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity

(2018) Janice S. Chen et al.   SCIENCE

Beyond Simple Cartoons: Challenges in Characterizing Electrochemical Biosensor Interfaces

(2018) Dan Bizzotto et al.   ACS Sensors

CRISPR-Cas12a-assisted nucleic acid detection

(2018) Shi-Yuan Li et al.   Cell Discovery

A low-cost paper-based synthetic biology platform for analyzing gut microbiota and host biomarkers

(2018) Melissa K. Takahashi et al.   Nature Communications

Nucleic acid detection with CRISPR-Cas13a/C2c2

(2017) Jonathan S. Gootenberg et al.   SCIENCE

Biosensing: CRISPR-powered diagnostics

(2017) Xiaolei Zuo et al.   Nature Biomedical Engineering

In Vitro Evaluation of CRISPR/Cas9 Function by an Electrochemiluminescent Assay

(2016) Weipeng Liu et al.   ANALYTICAL CHEMISTRY

Dynamic Modulation of DNA Hybridization Using Allosteric DNA Tetrahedral Nanostructures

(2016) Ping Song et al.   ANALYTICAL CHEMISTRY

Rapid, Low-Cost Detection of Zika Virus Using Programmable Biomolecular Components

(2016) Keith Pardee et al.   CELL

Ultrasensitive Electrochemical Detection of Nucleic Acids Based on the Dual-Signaling Electrochemical Ratiometric Method and Exonuclease III-Assisted Target Recycling Amplification Strategy

(2015) Erhu Xiong et al.   ANALYTICAL CHEMISTRY

Synthetic biology devices for in vitro and in vivo diagnostics

(2015) Shimyn Slomovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Paper-Based Synthetic Gene Networks

(2014) Keith Pardee et al.   CELL

DNA Nanostructure-Decorated Surfaces for Enhanced Aptamer-Target Binding and Electrochemical Cocaine Sensors

(2011) Yanli Wen et al.   ANALYTICAL CHEMISTRY

Using personal glucose meters and functional DNA sensors to quantify a variety of analytical targets

(2011) Yu Xiang et al.   Nature Chemistry