Heme Oxygenase-1 targeting exosomes for temozolomide resistant glioblastoma synergistic therapy

The role of the STAT3 signaling transduction pathways in radioresistance

(2022) Po-Chang Shih   PHARMACOLOGY & THERAPEUTICS

Cation‐Free siRNA Micelles as Effective Drug Delivery Platform and Potent RNAi Nanomedicines for Glioblastoma Therapy

(2021) Tong Jiang et al.   ADVANCED MATERIALS

Inflammatory tumor microenvironment responsive neutrophil exosomes-based drug delivery system for targeted glioma therapy

(2021) Jun Wang et al.   BIOMATERIALS

Temozolomide nano enabled medicine: promises made by the nanocarriers in glioblastoma therapy

(2021) P. Soma Yasaswi et al.   JOURNAL OF CONTROLLED RELEASE

The non-canonical effects of heme oxygenase-1, a classical fighter against oxidative stress

(2021) Jiajia Wu et al.   Redox Biology

An Automatable Hydrogel Culture Platform for Evaluating Efficacy of Antibody‐Based Therapeutics in Overcoming Chemoresistance

(2020) Anna Kletzmayr et al.   Biotechnology Journal

Extracellular vesicles as drug delivery systems: Why and how?

(2020) Omnia M. Elsharkasy et al.   ADVANCED DRUG DELIVERY REVIEWS

Nanomedicine to target multidrug resistant tumors

(2020) Elise Lepeltier et al.   DRUG RESISTANCE UPDATES

Natural ligand-receptor mediated loading of siRNA in milk derived exosomes

(2020) Shruti Shandilya et al.   JOURNAL OF BIOTECHNOLOGY

Targeting STAT3 in Cancer Immunotherapy

(2020) Sailan Zou et al.   Molecular Cancer

Blood-brain barrier–penetrating siRNA nanomedicine for Alzheimer’s disease therapy

(2020) Yutong Zhou et al.   Science Advances

Role of Notch Signaling Pathway in Glioblastoma Multiforme Pathogenesis

(2019) Riccardo Bazzoni et al.   Cancers

Exosomes Derived From Bone Mesenchymal Stem Cells Ameliorate Early Inflammatory Responses Following Traumatic Brain Injury

(2019) Haoqi Ni et al.   Frontiers in Neuroscience

Emerging Role of Mesenchymal Stem Cell-derived Exosomes in Regenerative Medicine

(2019) Ting Zhao et al.   Current Stem Cell Research & Therapy

Global, regional, and national burden of brain and other CNS cancer, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

(2019) Anoop P Patel et al.   LANCET NEUROLOGY

Intravenously Injected Mesenchymal Stem Cells Penetrate the Brain and Treat Inflammation-Induced Brain Damage and Memory Impairment in Mice

(2019) Olena Lykhmus et al.   Frontiers in Pharmacology

ROS‐Responsive Polymeric siRNA Nanomedicine Stabilized by Triple Interactions for the Robust Glioblastoma Combinational RNAi Therapy

(2019) Meng Zheng et al.   ADVANCED MATERIALS

Therapeutic Targeting of the Notch Pathway in Glioblastoma

(2019) Zachary Gersey et al.   World Neurosurgery

Mesenchymal stem cell-derived exosomes for clinical use

(2019) Mayela Mendt et al.   BONE MARROW TRANSPLANTATION

A STAT3-based gene signature stratifies glioma patients for targeted therapy

(2019) Melanie Si Yan Tan et al.   Nature Communications

NRP-1 targeted and cargo-loaded exosomes facilitate simultaneous imaging and therapy of glioma in vitro and in vivo

(2018) Gang Jia et al.   BIOMATERIALS

Glioblastoma and chemoresistance to alkylating agents: Involvement of apoptosis, autophagy, and unfolded protein response

(2018) Sabine Hombach-Klonisch et al.   PHARMACOLOGY & THERAPEUTICS

Nanotechnology-Based Strategies for siRNA Brain Delivery for Disease Therapy

(2018) Meng Zheng et al.   TRENDS IN BIOTECHNOLOGY

Intradermal delivery of STAT3 siRNA to treat melanoma via dissolving microneedles

(2018) Jingtong Pan et al.   Scientific Reports

The sinister face of heme oxygenase-1 in brain aging and disease

(2018) Hyman M. Schipper et al.   PROGRESS IN NEUROBIOLOGY

Effective and Targeted Human Orthotopic Glioblastoma Xenograft Therapy via a Multifunctional Biomimetic Nanomedicine

(2018) Yan Zou et al.   ADVANCED MATERIALS

Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer

(2017) Sushrut Kamerkar et al.   NATURE

Emerging potential of exosomes for treatment of traumatic brain injury

(2017) Ye Xiong et al.   Neural Regeneration Research

Concise Review: MSC-Derived Exosomes for Cell-Free Therapy

(2017) Donald G. Phinney et al.   STEM CELLS

A Cell-Surface Membrane Protein Signature for Glioblastoma

(2017) Dhimankrishna Ghosh et al.   Cell Systems

Extracellular vesicles for drug delivery

(2016) Pieter Vader et al.   ADVANCED DRUG DELIVERY REVIEWS

Oncogene Knockdown via Active Loading of Small RNAs into Extracellular Vesicles by Sonication

(2016) Tek N. Lamichhane et al.   Cellular and Molecular Bioengineering

Potential crosstalk of the interleukin-6-heme oxygenase-1-dependent mechanism involved in resistance to lenalidomide in multiple myeloma cells

(2016) Weibing Wu et al.   FEBS Journal

Synergy and translation of allogenic bone marrow stem cells after photodynamic treatment of rheumatoid arthritis with tetra sulfonatophenyl porphyrin and TiO2 nanowhiskers

(2016) Fawad U. Rehman et al.   Nano Research

TGFβ-Responsive HMOX1 Expression Is Associated with Stemness and Invasion in Glioblastoma Multiforme

(2016) Dhiman Ghosh et al.   STEM CELLS

The non-canonical functions of the heme oxygenases

(2016) Luca Vanella et al.   Oncotarget

Exosomes as therapeutic drug carriers and delivery vehicles across biological membranes: current perspectives and future challenges

(2016) Dinh Ha et al.   Acta Pharmaceutica Sinica B

Amyloid Beta-Mediated Hypomethylation of Heme Oxygenase 1 Correlates with Cognitive Impairment in Alzheimer’s Disease

(2016) Hye Youn Sung et al.   PLoS One

Drug encapsulated polymeric microspheres for intracranial tumor therapy: A review of the literature

(2015) J. Alaina Floyd et al.   ADVANCED DRUG DELIVERY REVIEWS

The Exosome - A Naturally Secreted Nanoparticle and its Application to Wound Healing

(2015) Sweta Rani et al.   ADVANCED MATERIALS

Biodistribution and delivery efficiency of unmodified tumor-derived exosomes

(2015) Tyson Smyth et al.   JOURNAL OF CONTROLLED RELEASE

Cell membrane-camouflaged nanoparticles for drug delivery

(2015) Brian T. Luk et al.   JOURNAL OF CONTROLLED RELEASE

Using exosomes, naturally-equipped nanocarriers, for drug delivery

(2015) Elena V. Batrakova et al.   JOURNAL OF CONTROLLED RELEASE

Extraction and Analysis of Silver and Gold Nanoparticles from Biological Tissues Using Single Particle Inductively Coupled Plasma Mass Spectrometry

(2013) Evan P. Gray et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Constitutive Activation of Signal Transducer and Activator of Transcription 3 (STAT3) and Nuclear Factor κB Signaling in Glioblastoma Cancer Stem Cells Regulates the Notch Pathway

(2013) Jo Meagan Garner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

STAT3 Inhibition Overcomes Temozolomide Resistance in Glioblastoma by Downregulating MGMT Expression

(2012) Shinji Kohsaka et al.   MOLECULAR CANCER THERAPEUTICS

Exosome-mediated delivery of siRNA in vitro and in vivo

(2012) Samir El-Andaloussi et al.   Nature Protocols

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(2011) Ilya Ulasov et al.   MOLECULAR MEDICINE

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY

Mesenchymal stem cells as cellular vehicles for delivery of nanoparticles to brain tumors

(2010) Mathilde Roger et al.   BIOMATERIALS

STAT3 Is Required for Proliferation and Maintenance of Multipotency in Glioblastoma Stem Cells

(2009) Maureen M. Sherry et al.   STEM CELLS

STAT3 as a target for inducing apoptosis in solid and hematological tumors

(2008) Khandaker Al Zaid Siddiquee et al.   CELL RESEARCH

Mechanisms of Disease: temozolomide and glioblastoma—look to the future

(2008) Maciej M Mrugala et al.   Nature clinical practice. Oncology