Pitavastatin-Incorporated Nanoparticles for Chronic Limb Threatening Ischemia: A Phase I/IIa Clinical Trial

Safety, Tolerability, and Pharmacokinetics of NK-104-NP

(2018) Kaku Nakano et al.   International Heart Journal

Nanoparticle-Mediated Targeting of Pitavastatin to Small Pulmonary Arteries and Leukocytes by Intravenous Administration Attenuates the Progression of Monocrotaline-Induced Established Pulmonary Arterial Hypertension in Rats

(2018) Kenzo Ichimura et al.   International Heart Journal

Nanoparticle-Mediated Delivery of Pitavastatin to Monocytes/Macrophages Inhibits Left Ventricular Remodeling After Acute Myocardial Infarction by Inhibiting Monocyte-Mediated Inflammation

(2017) Yajing Mao et al.   International Heart Journal

Anti-inflammatory Nanoparticle for Prevention of Atherosclerotic Vascular Diseases

(2016) Jun-ichiro Koga et al.   Journal of Atherosclerosis and Thrombosis

A Translational Study of a New Therapeutic Approach for Acute Myocardial Infarction: Nanoparticle-Mediated Delivery of Pitavastatin into Reperfused Myocardium Reduces Ischemia-Reperfusion Injury in a Preclinical Porcine Model

(2016) Kenzo Ichimura et al.   PLoS One

A New Therapeutic Modality for Acute Myocardial Infarction: Nanoparticle-Mediated Delivery of Pitavastatin Induces Cardioprotection from Ischemia-Reperfusion Injury via Activation of PI3K/Akt Pathway and Anti-Inflammation in a Rat Model

(2015) Kazuhiro Nagaoka et al.   PLoS One

Amelioration of Ischemic Mitochondrial Injury and Bax-Dependent Outer Membrane Permeabilization by Mdivi-1

(2014) Yan-Xin Zhao et al.   CNS Neuroscience & Therapeutics

Nanoparticle-Mediated Delivery of Pitavastatin Inhibits Atherosclerotic Plaque Destabilization/Rupture in Mice by Regulating the Recruitment of Inflammatory Monocytes

(2013) Shunsuke Katsuki et al.   CIRCULATION

Both autologous bone marrow mononuclear cell and peripheral blood progenitor cell therapies similarly improve ischaemia in patients with diabetic foot in comparison with control treatment

(2013) M. Dubsky et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Pitavastatin-Incorporated Nanoparticle-Eluting Stents Attenuate In-Stent Stenosis without Delayed Endothelial Healing Effects in a Porcine Coronary Artery Model

(2012) Noriaki Tsukie et al.   Journal of Atherosclerosis and Thrombosis

Nanoparticle-Mediated Delivery of Pitavastatin Into Lungs Ameliorates the Development and Induces Regression of Monocrotaline-Induced Pulmonary Artery Hypertension

(2011) Ling Chen et al.   HYPERTENSION

Effect of fibroblast growth factor NV1FGF on amputation and death: a randomised placebo-controlled trial of gene therapy in critical limb ischaemia

(2011) Jill Belch et al.   LANCET

A novel nucleic acid analogue shows strong angiogenic activity

(2010) Ikuko Tsukamoto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nanoparticle-mediated endothelial cell-selective delivery of pitavastatin induces functional collateral arteries (therapeutic arteriogenesis) in a rabbit model of chronic hind limb ischemia

(2010) Shinichiro Oda et al.   JOURNAL OF VASCULAR SURGERY

Therapeutic Neovascularization by Nanotechnology-Mediated Cell-Selective Delivery of Pitavastatin Into the Vascular Endothelium

(2009) Mitsuki Kubo et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Therapeutic Angiogenesis With Intramuscular NV1FGF Improves Amputation-free Survival in Patients With Critical Limb Ischemia

(2008) Sigrid Nikol et al.   MOLECULAR THERAPY