A Translational Study of a New Therapeutic Approach for Acute Myocardial Infarction: Nanoparticle-Mediated Delivery of Pitavastatin into Reperfused Myocardium Reduces Ischemia-Reperfusion Injury in a Preclinical Porcine Model

Pioglitazone-Incorporated Nanoparticles Prevent Plaque Destabilization and Rupture by Regulating Monocyte/Macrophage Differentiation inApoE−/−MiceSignificance

(2016) Soichi Nakashiro et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Relationship Between Infarct Size and Outcomes Following Primary PCI

(2016) Gregg W. Stone et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Nanoparticle-Mediated Targeting of Cyclosporine A Enhances Cardioprotection Against Ischemia-Reperfusion Injury Through Inhibition of Mitochondrial Permeability Transition Pore Opening

(2016) Gentaro Ikeda et al.   Scientific Reports

Nanoparticle-Mediated Delivery of Irbesartan Induces Cardioprotection from Myocardial Ischemia-Reperfusion Injury by Antagonizing Monocyte-Mediated Inflammation

(2016) Yasuhiro Nakano et al.   Scientific Reports

A New Therapeutic Modality for Acute Myocardial Infarction: Nanoparticle-Mediated Delivery of Pitavastatin Induces Cardioprotection from Ischemia-Reperfusion Injury via Activation of PI3K/Akt Pathway and Anti-Inflammation in a Rat Model

(2015) Kazuhiro Nagaoka et al.   PLoS One

Effect of ischemic postconditioning on microvascular obstruction in reperfused myocardial infarction. Results of a randomized study in patients and of an experimental model in swine

(2014) Vicente Bodi et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Mechanically Unloading the Left Ventricle Before Coronary Reperfusion Reduces Left Ventricular Wall Stress and Myocardial Infarct Size

(2013) Navin K. Kapur et al.   CIRCULATION

Validation of Contrast-Enhanced Magnetic Resonance Imaging to Monitor Regenerative Efficacy After Cell Therapy in a Porcine Model of Convalescent Myocardial Infarction

(2013) Konstantinos Malliaras et al.   CIRCULATION

Nanoparticle-Mediated Delivery of Pitavastatin Inhibits Atherosclerotic Plaque Destabilization/Rupture in Mice by Regulating the Recruitment of Inflammatory Monocytes

(2013) Shunsuke Katsuki et al.   CIRCULATION

Crucial Role of Calcium-Sensing Receptor Activation in Cardiac Injury of Diabetic Rats

(2013) Hanping Qi et al.   PLoS One

Recombinant mitochondrial transcription factor A protein inhibits nuclear factor of activated T cells signaling and attenuates pathological hypertrophy of cardiac myocytes

(2012) Takeo Fujino et al.   MITOCHONDRION

Nanoparticle-Mediated Delivery of Pitavastatin Into Lungs Ameliorates the Development and Induces Regression of Monocrotaline-Induced Pulmonary Artery Hypertension

(2011) Ling Chen et al.   HYPERTENSION

The in-situ pig heart with regional ischemia/reperfusion — Ready for translation

(2011) Gerd Heusch et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

PLGA nanoparticles containing various anticancer agents and tumour delivery by EPR effect

(2010) Sarbari Acharya et al.   ADVANCED DRUG DELIVERY REVIEWS

The Representative Porcine Model for Human Cardiovascular Disease

(2010) Yoriyasu Suzuki et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Nanoparticle-mediated endothelial cell-selective delivery of pitavastatin induces functional collateral arteries (therapeutic arteriogenesis) in a rabbit model of chronic hind limb ischemia

(2010) Shinichiro Oda et al.   JOURNAL OF VASCULAR SURGERY

Therapeutic Neovascularization by Nanotechnology-Mediated Cell-Selective Delivery of Pitavastatin Into the Vascular Endothelium

(2009) Mitsuki Kubo et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Statins and cardioprotection — More than just lipid lowering?

(2009) Andrew Ludman et al.   PHARMACOLOGY & THERAPEUTICS

Local Delivery of Imatinib Mesylate (STI571)-Incorporated Nanoparticle Ex Vivo Suppresses Vein Graft Neointima Formation

(2008) S. Kimura et al.   CIRCULATION