The role of NANOG transcriptional factor in the development of malignant phenotype of cancer cells

Snail regulates Nanog status during the epithelial–mesenchymal transition via the Smad1/Akt/GSK3β signaling pathway in non-small-cell lung cancer

(2015) Chen-Wei Liu et al.   Oncotarget

NANOG Amplifies STAT3 Activation and They Synergistically Induce the Naive Pluripotent Program

(2014) Hannah T. Stuart et al.   CURRENT BIOLOGY

Hepatitis C virus core protein regulates NANOG expression via the stat3 pathway

(2014) Jia-Jia Zhou et al.   FEBS LETTERS

Pancreatic tumour formation and recurrence after radiotherapy are blocked by targeting CD44

(2014) Natalie J. Wood   Nature Reviews Gastroenterology & Hepatology

On the Origin and Evolutionary History of NANOG

(2014) Pierluigi Scerbo et al.   PLoS One

SHP-1 Arrests Mouse Early Embryo Development through Downregulation of Nanog by Dephosphorylation of STAT3

(2014) Songna Yin et al.   PLoS One

Temporal regulation of mRNAs for select bone morphogenetic proteins (BMP), BMP receptors and their associated SMAD proteins during bovine early embryonic development: effects of exogenous BMP2 on embryo developmental progression

(2014) Kyung-Bon Lee et al.   Reproductive Biology and Endocrinology

Immunohistochemical expression of four different stem cell markers in prostate cancer: High expression of NANOG in conjunction with hypoxia-inducible factor-1α expression is involved in prostate epithelial malignancy

(2014) KATSUHITO MIYAZAWA et al.   Oncology Letters

MiR-134 regulates the proliferation and invasion of glioblastoma cells by reducing Nanog expression

(2013) CHAO SHI NIU et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Cutting Edge: Hypoxia-Induced Nanog Favors the Intratumoral Infiltration of Regulatory T Cells and Macrophages via Direct Regulation of TGF- 1

(2013) M. Hasmim et al.   JOURNAL OF IMMUNOLOGY

NPV-LDE-225 (Erismodegib) inhibits epithelial mesenchymal transition and self-renewal of glioblastoma initiating cells by regulating miR-21, miR-128, and miR-200

(2013) J. Fu et al.   NEURO-ONCOLOGY

Phosphorylation of Nanog is essential to regulate Bmi1 and promote tumorigenesis

(2013) X Xie et al.   ONCOGENE

Embryonic Stem Cells Markers SOX2, OCT4 and Nanog Expression and Their Correlations with Epithelial-Mesenchymal Transition in Nasopharyngeal Carcinoma

(2013) Weiren Luo et al.   PLoS One

CD271 Defines a Stem Cell-Like Population in Hypopharyngeal Cancer

(2013) Takayuki Imai et al.   PLoS One

NANOG expression correlates with differentiation, metastasis and resistance to preoperative adjuvant therapy in oral squamous cell carcinoma

(2013) MASAHIRO WATANABE et al.   Oncology Letters

Pluripotency transcription factors and cancer stem cells: small genes make a big difference

(2013) Anfei Liu et al.   Chinese Journal of Cancer

Coexpression of Stemness Factors Oct4 and Nanog Predict Liver Resection

(2012) Xin Yin et al.   ANNALS OF SURGICAL ONCOLOGY

Cancer stem-like cells contribute to cisplatin resistance and progression in bladder cancer

(2012) Yi Zhang et al.   CANCER LETTERS

Nanog: A Potential Biomarker for Liver Metastasis of Colorectal Cancer

(2012) Feng Xu et al.   DIGESTIVE DISEASES AND SCIENCES

Nanog regulates self-renewal of cancer stem cells through the insulin-like growth factor pathway in human hepatocellular carcinoma

(2012) Juanjuan Shan et al.   HEPATOLOGY

Nanog Increases Focal Adhesion Kinase (FAK) Promoter Activity and Expression and Directly Binds to FAK Protein to Be Phosphorylated

(2012) Baotran Ho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nanog and Oct4 overexpression increases motility and transmigration of melanoma cells

(2012) Aurelie Borrull et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Defining the mode of tumour growth by clonal analysis

(2012) Gregory Driessens et al.   NATURE

Stem cell transcription factor NANOG controls cell migration and invasion via dysregulation of E-cadherin and FoxJ1 and contributes to adverse clinical outcome in ovarian cancers

(2012) M K Y Siu et al.   ONCOGENE

Hypoxia Induced Aggressiveness of Prostate Cancer Cells Is Linked with Deregulated Expression of VEGF, IL-6 and miRNAs That Are Attenuated by CDF

(2012) Bin Bao et al.   PLoS One

Hypoxia-Induced Aggressiveness of Pancreatic Cancer Cells Is Due to Increased Expression of VEGF, IL-6 and miR-21, Which Can Be Attenuated by CDF Treatment

(2012) Bin Bao et al.   PLoS One

E-cadherin and, in Its Absence, N-cadherin Promotes Nanog Expression in Mouse Embryonic Stem Cells via STAT3 Phosphorylation

(2012) Kate Hawkins et al.   STEM CELLS

Expression of the pluripotency markers Oct3/4, Nanog and Sox2 in human breast cancer cell lines

(2012) GUI-QIN LING et al.   Oncology Letters

Differential expression of nanog1 and nanogp8 in colon cancer cells

(2011) Tatsuya Ishiguro et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Snail1 induces epithelial-to-mesenchymal transition and tumor initiating stem cell characteristics

(2011) Hien Dang et al.   BMC CANCER

CD24+ Liver Tumor-Initiating Cells Drive Self-Renewal and Tumor Initiation through STAT3-Mediated NANOG Regulation

(2011) Terence Kin Wah Lee et al.   Cell Stem Cell

Hypoxia-Dependent Inhibition of Tumor Cell Susceptibility to CTL-Mediated Lysis Involves NANOG Induction in Target Cells

(2011) Meriem Hasmim et al.   JOURNAL OF IMMUNOLOGY

Markedly increased Oct4 and Nanog expression correlates with cisplatin resistance in oral squamous cell carcinoma

(2011) Lo-Lin Tsai et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Overexpression of Nanog protein is associated with poor prognosis in gastric adenocarcinoma

(2011) Ting Lin et al.   MEDICAL ONCOLOGY

Cell growth arrest and apoptosis induced by Oct4 or Nanog knockdown in mouse embryonic stem cells: a possible role of Trp53

(2011) Tianji Chen et al.   MOLECULAR BIOLOGY REPORTS

Stem cell marker (Nanog) and Stat-3 signaling promote MicroRNA-21 expression and chemoresistance in hyaluronan/CD44-activated head and neck squamous cell carcinoma cells

(2011) L Y W Bourguignon et al.   ONCOGENE

MicroRNA let-7a represses chemoresistance and tumourigenicity in head and neck cancer via stem-like properties ablation

(2011) Cheng-Chia Yu et al.   ORAL ONCOLOGY

Switching on pluripotency: a perspective on the biological requirement of Nanog

(2011) T. W. Theunissen et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

5-Aminoimidazole-4-carboxyamide Ribonucleoside Induces G1/S Arrest and Nanog Downregulation via p53 and Enhances Erythroid Differentiation

(2011) Hee-Don Chae et al.   STEM CELLS

NANOG induction of fetal liver kinase-1 (FLK1) transcription regulates endothelial cell proliferation and angiogenesis

(2010) E. E. Kohler et al.   BLOOD

Coexpression of Oct4 and Nanog Enhances Malignancy in Lung Adenocarcinoma by Inducing Cancer Stem Cell-Like Properties and Epithelial-Mesenchymal Transdifferentiation

(2010) S.-H. Chiou et al.   CANCER RESEARCH

Hedgehog controls neural stem cells through p53-independent regulation of Nanog

(2010) Agnese Po et al.   EMBO JOURNAL

NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53

(2010) Marie Zbinden et al.   EMBO JOURNAL

Expression of NANOG and NANOGP8 in a variety of undifferentiated and differentiated human cells

(2010) Sakthikumar Ambady et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Transcriptional properties of human NANOG1 and NANOG2 in acute leukemic cells

(2010) Irina Eberle et al.   NUCLEIC ACIDS RESEARCH

Bmi-1 Regulates Snail Expression and Promotes Metastasis Ability in Head and Neck Squamous Cancer-Derived ALDH1 Positive Cells

(2010) Cheng-Chia Yu et al.   Journal of Oncology

Signal Transducer and Activator of Transcription-3, Inflammation, and Cancer

(2009) Bharat B. Aggarwal et al.   Annals of the New York Academy of Sciences

Depletion of Embryonic Stem Cell Signature by Histone Deacetylase Inhibitor in NCCIT Cells: Involvement of Nanog Suppression

(2009) J. S. You et al.   CANCER RESEARCH

Molecular Characterization of the Human NANOG Protein

(2009) David F. Chang et al.   STEM CELLS

Functional Evidence that the Self-Renewal GeneNANOGRegulates Human Tumor Development

(2009) Collene R. Jeter et al.   STEM CELLS

Novel STAT3 Target Genes Exert Distinct Roles in the Inhibition of Mesoderm and Endoderm Differentiation in Cooperation with Nanog

(2009) Pierre-Yves Bourillot et al.   STEM CELLS

Nogo-66 Regulates Nanog Expression Through Stat3 Pathway in Murine Embryonic Stem Cells

(2009) Yuan Gao et al.   STEM CELLS AND DEVELOPMENT

Induction of Stem Cell Gene Expression in Adult Human Fibroblasts without Transgenes

(2009) Raymond L. Page et al.   Cloning Stem Cells

Overexpression of NANOG in Gestational Trophoblastic Diseases

(2008) Michelle K.Y. Siu et al.   AMERICAN JOURNAL OF PATHOLOGY

Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells

(2008) Xi Chen et al.   CELL

SIRT1 Regulates Apoptosis and Nanog Expression in Mouse Embryonic Stem Cells by Controlling p53 Subcellular Localization

(2008) Myung-Kwan Han et al.   Cell Stem Cell

Hyaluronan-CD44 Interaction Activates Stem Cell Marker Nanog, Stat-3-mediated MDR1 Gene Expression, and Ankyrin-regulated Multidrug Efflux in Breast and Ovarian Tumor Cells

(2008) Lilly Y. W. Bourguignon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY