Intragenic anaplastic lymphoma kinase (ALK) rearrangements: Translocations as a novel mechanism ofALKactivation in neuroblastoma tumors
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Title
Intragenic anaplastic lymphoma kinase (ALK) rearrangements: Translocations as a novel mechanism ofALKactivation in neuroblastoma tumors
Authors
Keywords
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Journal
GENES CHROMOSOMES & CANCER
Volume 54, Issue 2, Pages 99-109
Publisher
Wiley
Online
2014-09-24
DOI
10.1002/gcc.22223
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Related references
Note: Only part of the references are listed.- Phosphoproteomic analysis of anaplastic lymphoma kinase (ALK) downstream signaling pathways identifies signal transducer and activator of transcription 3 as a functional target of activated ALK in neuroblastoma cells
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- Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes
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- Aberrant activation of ALK kinase by a novel truncated form ALK protein in neuroblastoma
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- High Anaplastic Lymphoma Kinase Immunohistochemical Staining in Neuroblastoma and Ganglioneuroblastoma Is an Independent Predictor of Poor Outcome
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- Integrative genomics viewer
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- (2010) Marta Jeison et al. AMERICAN JOURNAL OF PATHOLOGY
- Appearance of the Novel Activating F1174S ALK Mutation in Neuroblastoma Correlates with Aggressive Tumor Progression and Unresponsiveness to Therapy
- (2010) T. Martinsson et al. CANCER RESEARCH
- Meta-analysis of Neuroblastomas Reveals a Skewed ALK Mutation Spectrum in Tumors with MYCN Amplification
- (2010) S. De Brouwer et al. CLINICAL CANCER RESEARCH
- Optimizing the Detection of Lung Cancer Patients Harboring Anaplastic Lymphoma Kinase (ALK) Gene Rearrangements Potentially Suitable for ALK Inhibitor Treatment
- (2010) D. R. Camidge et al. CLINICAL CANCER RESEARCH
- Accumulation of Segmental Alterations Determines Progression in Neuroblastoma
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- Crizotinib inALK-Rearranged Inflammatory Myofibroblastic Tumor
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- (2010) John M. Maris NEW ENGLAND JOURNAL OF MEDICINE
- Anaplastic Lymphoma Kinase Inhibition in Non–Small-Cell Lung Cancer
- (2010) Eunice L. Kwak et al. NEW ENGLAND JOURNAL OF MEDICINE
- The genetic and clinical significance of MYCN gain as detected by FISH in neuroblastoma
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- High-risk neuroblastoma tumors with 11q-deletion display a poor prognostic, chromosome instability phenotype with later onset
- (2010) H. Caren et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Overall Genomic Pattern Is a Predictor of Outcome in Neuroblastoma
- (2009) Isabelle Janoueix-Lerosey et al. JOURNAL OF CLINICAL ONCOLOGY
- High incidence of DNA mutations and gene amplifications of theALKgene in advanced sporadic neuroblastoma tumours
- (2008) Helena Carén et al. BIOCHEMICAL JOURNAL
- Identification of ALK as a major familial neuroblastoma predisposition gene
- (2008) Yaël P. Mossé et al. NATURE
- Activating mutations in ALK provide a therapeutic target in neuroblastoma
- (2008) Rani E. George et al. NATURE
- Oncogenic mutations of ALK kinase in neuroblastoma
- (2008) Yuyan Chen et al. NATURE
- Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma
- (2008) Isabelle Janoueix-Lerosey et al. NATURE
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