Modulation of mitochondrial dynamics rescues cognitive function in rats with ‘doxorubicin‐induced chemobrain’ via mitigation of mitochondrial dysfunction and neuroinflammation

Mitochondrial Dynamics: A Key Role in Neurodegeneration and a Potential Target for Neurodegenerative Disease

(2021) Danying Yang et al.   Frontiers in Neuroscience

Donepezil Protects Against Doxorubicin-Induced Chemobrain in Rats via Attenuation of Inflammation and Oxidative Stress Without Interfering With Doxorubicin Efficacy

(2021) Benjamin Ongnok et al.   Neurotherapeutics

Chronic Peripheral Inflammation Causes a Region-Specific Myeloid Response in the Central Nervous System

(2020) Patrick Süß et al.   Cell Reports

Protective effects of diallyl trisulfide (DATS) against doxorubicin-induced inflammation and oxidative stress in the brain of rats

(2020) Wai-Shing Leung et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial Fusion Promoter Alleviates Brain Damage in Rats with Cardiac Ischemia/Reperfusion Injury

(2020) Poomarin Surinkaew et al.   JOURNAL OF ALZHEIMERS DISEASE

Astrocytes and microglia in neurodegenerative diseases: Lessons from human in vitro models

(2020) Hannah Franklin et al.   PROGRESS IN NEUROBIOLOGY

Neuroinflammation in neurodegenerative disorders: the roles of microglia and astrocytes

(2020) Hyuk Sung Kwon et al.   Translational Neurodegeneration

Changes in health-related quality of life among gynecologic cancer survivors during the two years after initial treatment: a longitudinal analysis

(2019) Nathalie Zandbergen et al.   ACTA ONCOLOGICA

N-acetyl cysteine, inulin and the two as a combined therapy ameliorate cognitive decline in testosterone-deprived rats

(2019) Titikorn Chunchai et al.   Aging-US

Attenuation of neuroinflammation reverses Adriamycin-induced cognitive impairments

(2019) Barrett D. Allen et al.   Acta Neuropathologica Communications

Doxorubicin and cisplatin induced cognitive impairment: The possible mechanisms and interventions

(2019) Benjamin Ongnok et al.   EXPERIMENTAL NEUROLOGY

Decreased microglial activation through gut-brain axis by prebiotics, probiotics, or synbiotics effectively restored cognitive function in obese-insulin resistant rats

(2018) Titikorn Chunchai et al.   Journal of Neuroinflammation

Microglial Ramification, Surveillance, and Interleukin-1β Release Are Regulated by the Two-Pore Domain K + Channel THIK-1

(2018) Christian Madry et al.   NEURON

Physical exercise prevents cognitive impairment by enhancing hippocampal neuroplasticity and mitochondrial function in doxorubicin-induced chemobrain

(2018) Hye-Sang Park et al.   NEUROPHARMACOLOGY

Doxorubicin-induced elevated oxidative stress and neurochemical alterations in brain and cognitive decline: protection by MESNA and insights into mechanisms of chemotherapy-induced cognitive impairment (“chemobrain”)

(2018) Jeriel T.R. Keeney et al.   Oncotarget

Mitochondrial dynamics in neuronal injury, development and plasticity

(2017) Kyle H. Flippo et al.   JOURNAL OF CELL SCIENCE

Astaxanthin Ameliorates Doxorubicin-Induced Cognitive Impairment (Chemobrain) in Experimental Rat Model: Impact on Oxidative, Inflammatory, and Apoptotic Machineries

(2017) Sara Emad El-Agamy et al.   MOLECULAR NEUROBIOLOGY

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Cancer treatment and survivorship statistics, 2016

(2016) Kimberly D. Miller et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Mitochondrial fission and fusion in secondary brain damage after CNS insults

(2016) Justin Balog et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

PET Evidence of the Effect of Donepezil on Cognitive Performance in an Animal Model of Chemobrain

(2016) Ilhan Lim et al.   Biomed Research International

Analyzing dendritic spine pathology in Alzheimer’s disease: problems and opportunities

(2015) Mario M. Dorostkar et al.   ACTA NEUROPATHOLOGICA

The Ambiguous Relationship of Oxidative Stress, Tau Hyperphosphorylation, and Autophagy Dysfunction in Alzheimer’s Disease

(2015) Zhenzhen Liu et al.   Oxidative Medicine and Cellular Longevity

Alternatively activated microglia and macrophages in the central nervous system

(2015) Rafael Franco et al.   PROGRESS IN NEUROBIOLOGY

Obesity Elicits Interleukin 1-Mediated Deficits in Hippocampal Synaptic Plasticity

(2014) J. R. Erion et al.   JOURNAL OF NEUROSCIENCE

Disturbed mitochondrial dynamics and neurodegenerative disorders

(2014) Florence Burté et al.   Nature Reviews Neurology

A meta-analysis of cognitive impairment following adult cancer chemotherapy.

(2014) Oana C. Lindner et al.   NEUROPSYCHOLOGY

Brain inflammation induces post-synaptic changes during early synapse formation in adult-born hippocampal neurons

(2013) Deepti Chugh et al.   EXPERIMENTAL NEUROLOGY

DPP-4 inhibitors improve cognition and brain mitochondrial function of insulin-resistant rats

(2013) Hiranya Pintana et al.   JOURNAL OF ENDOCRINOLOGY

Preservation of RNA and DNA from mammal samples under field conditions

(2013) Miguel Camacho-Sanchez et al.   Molecular Ecology Resources

Why size matters – balancing mitochondrial dynamics in Alzheimer's disease

(2013) Brian DuBoff et al.   TRENDS IN NEUROSCIENCES

Oxidative lipid modification of nicastrin enhances amyloidogenic γ-secretase activity in Alzheimer’s disease

(2012) A-Ryeong Gwon et al.   AGING CELL

A Small Molecule Promotes Mitochondrial Fusion in Mammalian Cells

(2012) Danling Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reduced hippocampal volume and verbal memory performance associated with interleukin-6 and tumor necrosis factor-alpha levels in chemotherapy-treated breast cancer survivors

(2012) Shelli Kesler et al.   BRAIN BEHAVIOR AND IMMUNITY

Meta-Analysis of Cognitive Functioning in Breast Cancer Survivors Previously Treated With Standard-Dose Chemotherapy

(2012) Heather S.L. Jim et al.   JOURNAL OF CLINICAL ONCOLOGY

Oxidative Stress Biomarkers in Some Rat Brain Structures and Peripheral Organs Underwent Cocaine

(2012) Lucyna Pomierny-Chamioło et al.   NEUROTOXICITY RESEARCH

Mitochondrial Fission, Fusion, and Stress

(2012) R. J. Youle et al.   SCIENCE

PPARγ Agonist Improves Neuronal Insulin Receptor Function in Hippocampus and Brain Mitochondria Function in Rats with Insulin Resistance Induced by Long Term High-Fat Diets

(2011) Noppamas Pipatpiboon et al.   ENDOCRINOLOGY

2-Mercaptoethane sulfonate prevents doxorubicin-induced plasma protein oxidation and TNF-α release: Implications for the reactive oxygen species-mediated mechanisms of chemobrain

(2011) Christopher D. Aluise et al.   FREE RADICAL BIOLOGY AND MEDICINE

Bcl-xLincreases mitochondrial fission, fusion, and biomass in neurons

(2009) Sarah B. Berman et al.   JOURNAL OF CELL BIOLOGY

BK channel openers inhibit ROS production of isolated rat brain mitochondria

(2008) Bogusz Kulawiak et al.   EXPERIMENTAL NEUROLOGY

Evidence that γ-secretase mediates oxidative stress-induced β-secretase expression in Alzheimer's disease

(2008) Dong-Gyu Jo et al.   NEUROBIOLOGY OF AGING

Very rapid quantification of malondialdehyde (MDA) in rat brain exposed to lead, aluminium and phenolic antioxidants by high-performance liquid chromatography-fluorescence detection

(2008) N. Candan et al.   NEUROTOXICOLOGY