Synergistic activity of antibodies in the multicomponent 4CMenB vaccine

Complement interactions with the pathogenic Neisseriae: clinical features, deficiency states, and evasion mechanisms

(2020) Lisa A. Lewis et al.   FEBS LETTERS

Synergic complement‐mediated bactericidal activity of monoclonal antibodies with distinct specificity

(2020) Eriberto Noel Natali et al.   FASEB JOURNAL

Genetic Meningococcal Antigen Typing System (gMATS): A genotyping tool that predicts 4CMenB strain coverage worldwide

(2019) Alessandro Muzzi et al.   VACCINE

Immunogenicity profiling of protein antigens from capsular group B Neisseria meningitidis

(2019) Amaka M. Awanye et al.   Scientific Reports

A review of the immunogenicity, safety and current recommendations for the meningococcal serogroup B vaccine, MenB‐FHbp

(2019) Cynthia Burman et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Does vaccination with 4CMenB convey protection against meningococcal serogroup B strains not predicted to be covered by MATS? A study of the UK clonal complex cc269

(2019) Maria Stella et al.   Human Vaccines & Immunotherapeutics

Human protective response induced by meningococcus B vaccine is mediated by the synergy of multiple bactericidal epitopes

(2018) M. Giuliani et al.   Scientific Reports

Cross-protection induced by VA-MENGOC-BC® vaccine

(2018) Rolando Felipe Ochoa-Azze   Human Vaccines & Immunotherapeutics

Breadth of coverage against a panel of 110 invasive disease isolates, immunogenicity and safety for 2 and 3 doses of an investigational MenABCWY vaccine in US adolescents – Results from a randomized, controlled, observer-blind phase II study

(2018) Jo Anne Welsch et al.   VACCINE

The serogroup B meningococcal vaccine Bexsero elicits antibodies to Neisseria gonorrhoeae

(2018) Evgeny A Semchenko et al.   CLINICAL INFECTIOUS DISEASES

The Global Meningococcal Initiative meeting on prevention of meningococcal disease worldwide: Epidemiology, surveillance, hypervirulent strains, antibiotic resistance and high-risk populations

(2018) Reinaldo Acevedo et al.   Expert Review of Vaccines

Effectiveness of a group B outer membrane vesicle meningococcal vaccine against gonorrhoea in New Zealand: a retrospective case-control study

(2017) Helen Petousis-Harris et al.   LANCET

Durability of immunogenicity and strain coverage of MenBvac, a meningococcal vaccine based on outer membrane vesicles: Lessons of the Normandy campaign

(2017) Julien Sevestre et al.   VACCINE

The role of anti-NHba antibody in bactericidal activity elicited by the meningococcal serogroup B vaccine, MenB-4C

(2017) Elizabeth Partridge et al.   VACCINE

Neisseria meningitidis factor H-binding protein bound to monoclonal antibody JAR5: implications for antibody synergy

(2016) E. Malito et al.   BIOCHEMICAL JOURNAL

The Global Evolution of Meningococcal Epidemiology Following the Introduction of Meningococcal Vaccines

(2016) Stephen I. Pelton   JOURNAL OF ADOLESCENT HEALTH

Dissection of the function of the RmpM periplasmic protein from Neisseria meningitidis

(2016) Sunil Maharjan et al.   MICROBIOLOGY-SGM

Expression of factor H binding protein in meningococcal strains can vary at least 15-fold and is genetically determined

(2016) Massimiliano Biagini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distribution of Bexsero® Antigen Sequence Types (BASTs) in invasive meningococcal disease isolates: Implications for immunisation

(2016) Carina Brehony et al.   VACCINE

Clinical experience with the meningococcal B vaccine, Bexsero ® : Prospects for reducing the burden of meningococcal serogroup B disease

(2016) Philip S. Watson et al.   VACCINE

Structure of the Neisseria meningitidis Type IV pilus

(2016) Subramania Kolappan et al.   Nature Communications

A Large Portion of Meningococcal Antigen Typing System-Negative Meningococcal Strains from Spain Is Killed by Sera from Adolescents and Infants Immunized with 4CMenB

(2015) R. Abad et al.   Clinical and Vaccine Immunology

Binding of Complement Factor H to PorB3 and NspA Enhances Resistance of Neisseria meningitidis to Anti-Factor H Binding Protein Bactericidal Activity

(2015) Serena Giuntini et al.   INFECTION AND IMMUNITY

A novel meningococcal outer membrane vesicle vaccine with constitutive expression of FetA: A phase I clinical trial

(2015) L. Marsay et al.   JOURNAL OF INFECTION

FetA Antibodies Induced by an Outer Membrane Vesicle Vaccine Derived from a Serogroup B Meningococcal Isolate with Constitutive FetA Expression

(2015) Holly Sanders et al.   PLoS One

MATS: Global coverage estimates for 4CMenB, a novel multicomponent meningococcal B vaccine

(2015) Duccio Medini et al.   VACCINE

Development and Use of a Serum Bactericidal Assay Using Pooled Human Complement To Assess Responses to a Meningococcal Group A Conjugate Vaccine in African Toddlers

(2014) Margaret C. Bash et al.   Clinical and Vaccine Immunology

Recombinant Protein Truncation Strategy for Inducing Bactericidal Antibodies to the Macrophage Infectivity Potentiator Protein of Neisseria meningitidis and Circumventing Potential Cross-Reactivity with Human FK506-Binding Proteins

(2014) Magdalena K. Bielecka et al.   INFECTION AND IMMUNITY

Recombinant Neisseria surface protein A is a potential vaccine candidate against Neisseria meningitides serogroup B

(2014) SHANGYUN YING et al.   Molecular Medicine Reports

Complement Is Activated by IgG Hexamers Assembled at the Cell Surface

(2014) C. A. Diebolder et al.   SCIENCE

Immuno-proteomic analysis of human immune responses to experimental Neisseria meningitidis outer membrane vesicle vaccines identifies potential cross-reactive antigens

(2014) Jeannette N. Williams et al.   VACCINE

Quantification by LC–MSE of outer membrane vesicle proteins of the Bexsero® vaccine

(2014) Chiara Tani et al.   VACCINE

A phase II randomized controlled trial of a multicomponent meningococcal serogroup B vaccine, 4CMenB, in infants (II)

(2014) Susanna Esposito et al.   Human Vaccines & Immunotherapeutics

A phase 2 randomized controlled trial of a multicomponent meningococcal serogroup B vaccine (I)

(2014) Roman Prymula et al.   Human Vaccines & Immunotherapeutics

Potential of the adhesin complex protein ofNeisseria meningitidisfor next-generation meningococcal vaccines

(2013) Miao-Chiu Hung et al.   Expert Review of Vaccines

Two cross-reactive monoclonal antibodies recognize overlapping epitopes on Neisseria meningitidis factor H binding protein but have different functional properties

(2013) Agnese Faleri et al.   FASEB JOURNAL

Meningococcal Omp85 in Detergent-Extracted Outer Membrane Vesicle Vaccines Induces High Levels of Non-Functional Antibodies in Mice

(2013) E. Wedege et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Bactericidal antibody against a representative epidemiological meningococcal serogroup B panel confirms that MATS underestimates 4CMenB vaccine strain coverage

(2013) Giacomo Frosi et al.   VACCINE

Factor H-Dependent Alternative Pathway Inhibition Mediated by Porin B Contributes to Virulence of Neisseria meningitidis

(2013) L. A. Lewis et al.   mBio

The Adhesin Complex Protein (ACP) of Neisseria meningitidis Is a New Adhesin with Vaccine Potential

(2013) M.-C. Hung et al.   mBio

Vaccines against meningococcal serogroup B disease containing outer membrane vesicles (OMV): Lessons from past programs and implications for the future

(2013) Johan Holst et al.   Human Vaccines & Immunotherapeutics

Recombinant outer membrane secretin PilQ406–770 as a vaccine candidate for serogroup B Neisseria meningitidis

(2012) Fakhri Haghi et al.   VACCINE

The Neisseria meningitidis Macrophage Infectivity Potentiator Protein Induces Cross-Strain Serum Bactericidal Activity and Is a Potential Serogroup B Vaccine Candidate

(2011) Miao-Chiu Hung et al.   INFECTION AND IMMUNITY

Effectiveness of a vaccination programme for an epidemic of meningococcal B in New Zealand

(2011) Richard Arnold et al.   VACCINE

Cooperative serum bactericidal activity between human antibodies to meningococcal factor H binding protein and Neisserial heparin binding antigen

(2011) David M. Vu et al.   VACCINE

A phase 1 study of a meningococcal native outer membrane vesicle vaccine made from a group B strain with deleted lpxL1 and synX, over-expressed factor H binding protein, two PorAs and stabilized OpcA expression

(2011) P.B. Keiser et al.   VACCINE

Multicenter, Open‐Label, Randomized Phase II Controlled Trial of an Investigational Recombinant Meningococcal Serogroup B Vaccine With and Without Outer Membrane Vesicles, Administered in Infancy

(2010) Jamie Findlow et al.   CLINICAL INFECTIOUS DISEASES

Immunogenicity of 2 Investigational Serogroup B Meningococcal Vaccines in the First Year of Life

(2010) Matthew D. Snape et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans

(2010) Davide Serruto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Qualitative and quantitative assessment of meningococcal antigens to evaluate the potential strain coverage of protein-based vaccines

(2010) J. Donnelly et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A phase 1 study of a group B meningococcal native outer membrane vesicle vaccine made from a strain with deleted lpxL2 and synX and stable expression of opcA

(2010) Paul B. Keiser et al.   VACCINE

Measuring antigen-specific bactericidal responses to a multicomponent vaccine against serogroup B meningococcus

(2010) Marzia M. Giuliani et al.   VACCINE

The Meningococcal Vaccine Candidate Neisserial Surface Protein A (NspA) Binds to Factor H and Enhances Meningococcal Resistance to Complement

(2010) Lisa A. Lewis et al.   PLoS Pathogens

Immunoproteomic Analysis of the Development of Natural Immunity in Subjects Colonized by Neisseria meningitidis Reveals Potential Vaccine Candidates

(2009) J. N. Williams et al.   INFECTION AND IMMUNITY

Neisseria meningitidis antigen NMB0088: sequence variability, protein topology and vaccine potential

(2009) G. Sardinas et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Complement evasion strategies of pathogens—Acquisition of inhibitors and beyond

(2009) Anna M. Blom et al.   MOLECULAR IMMUNOLOGY

Towards the Immunoproteome of Neisseria meningitidis

(2009) Tom A. Mendum et al.   PLoS One

Properties and clinical performance of vaccines containing outer membrane vesicles from Neisseria meningitidis

(2009) Johan Holst et al.   VACCINE

Fine Antigenic Specificity and Cooperative Bactericidal Activity of Monoclonal Antibodies Directed at the Meningococcal Vaccine Candidate Factor H-Binding Protein

(2008) P. T. Beernink et al.   INFECTION AND IMMUNITY