Small molecule neurolysin activators, potential multi-mechanism agents for ischemic stroke therapy

Structure-activity relationship studies of functionalized aromatic peptidomimetics as neurolysin activators

(2022) Md. Shafikur Rahman et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Discovery of First-in-Class Peptidomimetic Neurolysin Activators Possessing Enhanced Brain Penetration and Stability

(2021) Md. Shafikur Rahman et al.   JOURNAL OF MEDICINAL CHEMISTRY

Identification and characterization of two structurally related dipeptides that enhance catalytic efficiency of neurolysin

(2021) Srinidhi Jayaraman et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Peptidase neurolysin functions to preserve the brain after ischemic stroke in male mice

(2019) Srinidhi Jayaraman et al.   JOURNAL OF NEUROCHEMISTRY

Peptidase neurolysin is an endogenous cerebroprotective mechanism in acute neurodegenerative disorders

(2019) Vardan T. Karamyan   MEDICAL HYPOTHESES

Mechanism of Peptide Binding and Cleavage by the Human Mitochondrial Peptidase Neurolysin

(2018) Pedro F. Teixeira et al.   JOURNAL OF MOLECULAR BIOLOGY

Neurolysin: From Initial Detection to Latest Advances

(2018) Frédéric Checler et al.   NEUROCHEMICAL RESEARCH

Preparation and preliminary characterization of recombinant neurolysin for in vivo studies

(2016) Naomi J. Wangler et al.   JOURNAL OF BIOTECHNOLOGY

Functional up-regulation of endopeptidase neurolysin during post-acute and early recovery phases of experimental stroke in mouse brain

(2013) Mamoon Rashid et al.   JOURNAL OF NEUROCHEMISTRY

Identification of Membrane-bound Variant of Metalloendopeptidase Neurolysin (EC 3.4.24.16) as the Non-angiotensin Type 1 (Non-AT1), Non-AT2Angiotensin Binding Site

(2011) Naomi J. Wangler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stroke research at a crossroad: asking the brain for directions

(2011) Costantino Iadecola et al.   NATURE NEUROSCIENCE

Emerging Therapies: Pleiotropic Multi-target Drugs to Treat Stroke Victims

(2011) Paul A. Lapchak   Translational Stroke Research

Association of the Novel Non-AT1, Non-AT2 Angiotensin Binding Site with Neuronal Cell Death

(2010) M. Rashid et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS