Future Directions in Bronchiectasis Research

Neutrophil extracellular traps, disease severity, and antibiotic response in bronchiectasis: an international, observational, multicohort study

(2021) Holly R Keir et al.   Lancet Respiratory Medicine

Integrative microbiomics in bronchiectasis exacerbations

(2021) Micheál Mac Aogáin et al.   NATURE MEDICINE

C-Reactive Protein Concentration in Steady-State Bronchiectasis: Prognostic Value of Future Severe Exacerbations. Data From the Spanish Registry of Bronchiectasis (RIBRON)

(2020) Tomás Posadas et al.   ARCHIVOS DE BRONCONEUMOLOGIA

Sputum neutrophil elastase in bronchiectasis: a Southern European cohort study

(2020) Andrea Gramegna et al.   EUROPEAN RESPIRATORY JOURNAL

Sputum Neutrophil Elastase associates with microbiota and P. aeruginosa in bronchiectasis

(2020) Martina Oriano et al.   EUROPEAN RESPIRATORY JOURNAL

Mucin secretion in cystic fibrosis – a systematic review

(2020) Yaron Niv et al.   DIGESTIVE DISEASES

Phase 2 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis

(2020) James D. Chalmers et al.   NEW ENGLAND JOURNAL OF MEDICINE

Airway Bacterial Load and Inhaled Antibiotic Response in Bronchiectasis

(2019) Oriol Sibila et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Pregnancy Zone Protein is Associated with Airway Infection, Neutrophil Extracellular Trap Formation and Disease Severity in Bronchiectasis

(2019) Simon Finch et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Antimicrobial peptides, disease severity and exacerbations in bronchiectasis

(2019) Oriol Sibila et al.   THORAX

Airway Mucus Hyperconcentration in Non-Cystic Fibrosis Bronchiectasis

(2019) Kathryn A Ramsey et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial

(2019) Harry G M Heijerman et al.   LANCET

Bronchiectasis: new therapies and new perspectives

(2018) James D Chalmers et al.   Lancet Respiratory Medicine

Treatable traits in bronchiectasis

(2018) Rita Boaventura et al.   EUROPEAN RESPIRATORY JOURNAL

Advances in bronchiectasis: endotyping, genetics, microbiome, and disease heterogeneity

(2018) Patrick A Flume et al.   LANCET

Bronchiectasis

(2018) James D. Chalmers et al.   Nature Reviews Disease Primers

Pseudomonas aeruginosaadaptation and diversification in the non-cystic fibrosis bronchiectasis lung

(2017) Yasmin Hilliam et al.   EUROPEAN RESPIRATORY JOURNAL

Precision medicine in airway diseases: moving to clinical practice

(2017) Alvar Agustí et al.   EUROPEAN RESPIRATORY JOURNAL

The microbiome in respiratory medicine: current challenges and future perspectives

(2017) Rosa Faner et al.   EUROPEAN RESPIRATORY JOURNAL

European Respiratory Society guidelines for the management of adult bronchiectasis

(2017) Eva Polverino et al.   EUROPEAN RESPIRATORY JOURNAL

The heterogeneity of systemic inflammation in bronchiectasis

(2017) Aarash D. Saleh et al.   RESPIRATORY MEDICINE

The past decade in bench research into pulmonary infectious diseases: What do clinicians need to know?

(2017) Simon Finch et al.   RESPIROLOGY

Antimicrobial Peptides and Innate Lung Defenses

(2016) Pieter S. Hiemstra et al.   CHEST

Research priorities in bronchiectasis: a consensus statement from the EMBARC Clinical Research Collaboration

(2016) Stefano Aliberti et al.   EUROPEAN RESPIRATORY JOURNAL

Treatable traits: toward precision medicine of chronic airway diseases

(2016) Alvar Agusti et al.   EUROPEAN RESPIRATORY JOURNAL

Changes in the incidence, prevalence and mortality of bronchiectasis in the UK from 2004 to 2013: a population-based cohort study

(2015) Jennifer K. Quint et al.   EUROPEAN RESPIRATORY JOURNAL

Neutrophilic Bronchial Inflammation Correlates with Clinical and Functional Findings in Patients with Noncystic Fibrosis Bronchiectasis

(2015) Federico L. Dente et al.   MEDIATORS OF INFLAMMATION

Precision Medicine — Personalized, Problematic, and Promising

(2015) J. Larry Jameson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sputum matrix metalloproteinase-8 and -9 and tissue inhibitor of metalloproteinase-1 in bronchiectasis: Clinical correlates and prognostic implications

(2015) Wei-jie Guan et al.   RESPIROLOGY

Secreted mucins and airway bacterial colonization in non-CF bronchiectasis

(2015) Oriol Sibila et al.   RESPIROLOGY

Network medicine, multimorbidity and the lung in the elderly

(2014) R. Faner et al.   EUROPEAN RESPIRATORY JOURNAL

Remodelling the extracellular matrix in development and disease

(2014) Caroline Bonnans et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Sputum colour in non-CF bronchiectasis: The original neutrophil biomarker

(2013) James D Chalmers et al.   RESPIROLOGY

The role of matrix metalloproteinases in cystic fibrosis lung disease

(2011) A. Gaggar et al.   EUROPEAN RESPIRATORY JOURNAL

Addressing the Complexity of Chronic Obstructive Pulmonary Disease

(2010) Alvar Agusti et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Antimicrobial Peptides: Primeval Molecules or Future Drugs?

(2010) Brian M. Peters et al.   PLoS Pathogens

Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis

(2009) Darren M Hutt et al.   Nature Chemical Biology

MUC5B Is the Major Mucin in the Gel Phase of Sputum in Chronic Obstructive Pulmonary Disease

(2008) Sara Kirkham et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Bronquiectasias, inflamación sistémica y factor de necrosis tumoral alfa: factores asociados

(2008) Miguel Ángel Martínez-García et al.   ARCHIVOS DE BRONCONEUMOLOGIA

Endotyping asthma: new insights into key pathogenic mechanisms in a complex, heterogeneous disease

(2008) Gary P Anderson   LANCET