Engineered Iron-Based nanoplatform amplifies repolarization of M2-Like Tumor-Associated Macrophages for enhanced cancer immunotherapy

Boosting anti-PD-1 therapy with metformin-loaded macrophage-derived microparticles

(2021) Zhaohan Wei et al.   Nature Communications

High-resolution T1 MRI via renally clearable dextran nanoparticles with an iron oxide shell

(2021) Tae-Hyun Shin et al.   Nature Biomedical Engineering

Human chimeric antigen receptor macrophages for cancer immunotherapy

(2020) Michael Klichinsky et al.   NATURE BIOTECHNOLOGY

Platelet Membrane‐Camouflaged Magnetic Nanoparticles for Ferroptosis‐Enhanced Cancer Immunotherapy

(2020) Qin Jiang et al.   Small

Nanoscale Metal–Organic Frameworks for Cancer Immunotherapy

(2020) Kaiyuan Ni et al.   ACCOUNTS OF CHEMICAL RESEARCH

Activating Macrophage‐Mediated Cancer Immunotherapy by Genetically Edited Nanoparticles

(2020) Lang Rao et al.   ADVANCED MATERIALS

Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms

(2020) Christian B. Billesbølle et al.   NATURE

Acceptor Engineering for Optimized ROS Generation Facilitates Reprogramming Macrophages to M1 Phenotype in Photodynamic Immunotherapy

(2020) Guang Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tumour-associated macrophages-derived CXCL8 determines immune evasion through autonomous PD-L1 expression in gastric cancer

(2019) Chao Lin et al.   GUT

Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47−mediated ‘don’t-eat-me’ signal

(2019) Mingen Liu et al.   NATURE IMMUNOLOGY

FDA-approved ferumoxytol displays anti-leukaemia efficacy against cells with low ferroportin levels

(2019) Vicenta Trujillo-Alonso et al.   Nature Nanotechnology

Tailoring Nanomaterials for Targeting Tumor‐Associated Macrophages

(2019) Muhammad Ovais et al.   ADVANCED MATERIALS

Fe3O4@Astragalus Polysaccharide Core–Shell Nanoparticles for Iron Deficiency Anemia Therapy and Magnetic Resonance Imaging in Vivo

(2019) Kai Wang et al.   ACS Applied Materials & Interfaces

Targeting Tumor-Associated Macrophages in Cancer

(2019) Paulina Pathria et al.   TRENDS IN IMMUNOLOGY

Macrophages and Metabolism in the Tumor Microenvironment

(2019) Ilio Vitale et al.   Cell Metabolism

LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy

(2019) Mónica Pascual-García et al.   Nature Communications

A toll-like receptor agonist mimicking microbial signal to generate tumor-suppressive macrophages

(2019) Yanxian Feng et al.   Nature Communications

Nanoscale Metal-Organic Framework Mediates Radical Therapy to Enhance Cancer Immunotherapy

(2019) Kaiyuan Ni et al.   Chem

Amplified Cancer Immunotherapy of a Surface-Engineered Antigenic Microparticle Vaccine by Synergistically Modulating Tumor Microenvironment

(2019) Hongjuan Zhao et al.   ACS Nano

Iron chelated melanin-like nanoparticles for tumor-associated macrophage repolarization and cancer therapy

(2019) Lei Rong et al.   BIOMATERIALS

Engineered nano-immunopotentiators efficiently promote cancer immunotherapy for inhibiting and preventing lung metastasis of melanoma

(2019) Lijia Luo et al.   BIOMATERIALS

Chloroquine modulates antitumor immune response by resetting tumor-associated macrophages toward M1 phenotype

(2018) Degao Chen et al.   Nature Communications

TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy

(2018) Christopher B. Rodell et al.   Nature Biomedical Engineering

Targeting macrophages: therapeutic approaches in cancer

(2018) Luca Cassetta et al.   NATURE REVIEWS DRUG DISCOVERY

Imatinib and spironolactone suppress hepcidin expression

(2017) Katarzyna Mleczko-Sanecka et al.   HAEMATOLOGICA

Reprogramming Tumor-Associated Macrophages To Reverse EGFRT790M Resistance by Dual-Targeting Codelivery of Gefitinib/Vorinostat

(2017) Huige Peng et al.   NANO LETTERS

Tumour-associated macrophages as treatment targets in oncology

(2017) Alberto Mantovani et al.   Nature Reviews Clinical Oncology

Exceedingly small iron oxide nanoparticles as positive MRI contrast agents

(2017) He Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Imatinib and spironolactone suppress hepcidin expression

(2017) Katarzyna Mleczko-Sanecka et al.   HAEMATOLOGICA

Iron Induces Anti-tumor Activity in Tumor-Associated Macrophages

(2017) Milene Costa da Silva et al.   Frontiers in Immunology

Iron Handling in Tumor-Associated Macrophages—Is There a New Role for Lipocalin-2?

(2017) Michaela Jung et al.   Frontiers in Immunology

Nanoscale metal–organic frameworks for phototherapy of cancer

(2017) Guangxu Lan et al.   COORDINATION CHEMISTRY REVIEWS

Tumor-associated macrophages: Potential therapeutic targets for anti-cancer therapy

(2016) Yoshihiro Komohara et al.   ADVANCED DRUG DELIVERY REVIEWS

A Breakthrough: Macrophage-Directed Cancer Immunotherapy

(2016) C. D. Mills et al.   CANCER RESEARCH

Size-Controlled Synthesis of Porphyrinic Metal–Organic Framework and Functionalization for Targeted Photodynamic Therapy

(2016) Jihye Park et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iron oxide nanoparticles inhibit tumour growth by inducing pro-inflammatory macrophage polarization in tumour tissues

(2016) Saeid Zanganeh et al.   Nature Nanotechnology

In vivo MR and Fluorescence Dual-modality Imaging of Atherosclerosis Characteristics in Mice Using Profilin-1 Targeted Magnetic Nanoparticles

(2016) Yabin Wang et al.   Theranostics

Targeting myeloid cells using nanoparticles to improve cancer immunotherapy

(2015) Zohreh Amoozgar et al.   ADVANCED DRUG DELIVERY REVIEWS

Dual Targeted Immunotherapy via In Vivo Delivery of Biohybrid RNAi-Peptide Nanoparticles to Tumor-Associated Macrophages and Cancer Cells

(2015) João Conde et al.   ADVANCED FUNCTIONAL MATERIALS

Ironing out Ferroportin

(2015) Hal Drakesmith et al.   Cell Metabolism

Targeted delivery of proapoptotic peptides to tumor-associated macrophages improves survival

(2013) M. Cieslewicz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zirconium-Metalloporphyrin PCN-222: Mesoporous Metal-Organic Frameworks with Ultrahigh Stability as Biomimetic Catalysts

(2012) Dawei Feng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

High-Resolution Magnetic Resonance Imaging Enhanced With Superparamagnetic Nanoparticles Measures Macrophage Burden in Atherosclerosis

(2010) Kunio Morishige et al.   CIRCULATION

Differential regulation of iron homeostasis during human macrophage polarized activation

(2009) Stefania Recalcati et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Ferumoxytol: A New Intravenous Iron Preparation for the Treatment of Iron Deficiency Anemia in Patients with Chronic Kidney Disease

(2009) Michael H Schwenk   PHARMACOTHERAPY