Dual Targeted Immunotherapy via In Vivo Delivery of Biohybrid RNAi-Peptide Nanoparticles to Tumor-Associated Macrophages and Cancer Cells

Target-responsive DNA/RNA nanomaterials for microRNA sensing and inhibition: The jack-of-all-trades in cancer nanotheranostics?

(2015) João Conde et al.   ADVANCED DRUG DELIVERY REVIEWS

Cancer statistics, 2014

(2014) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Antibody–drug gold nanoantennas with Raman spectroscopic fingerprints for in vivo tumour theranostics

(2014) João Conde et al.   JOURNAL OF CONTROLLED RELEASE

Suppression of nanoparticle cytotoxicity approaching in vivo serum concentrations: limitations of in vitro testing for nanosafety

(2014) Jong Ah Kim et al.   Nanoscale

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid

(2014) Oscar R. Colegio et al.   NATURE

In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight

(2014) James E. Dahlman et al.   Nature Nanotechnology

CD163 Expression Was Associated with Angiogenesis and Shortened Survival in Patients with Uniformly Treated Classical Hodgkin Lymphoma

(2014) Young Wha Koh et al.   PLoS One

Therapeutic Inflammatory Monocyte Modulation Using Immune-Modifying Microparticles

(2014) D. R. Getts et al.   Science Translational Medicine

Gold-nanobeacons for simultaneous gene specific silencing and intracellular tracking of the silencing events

(2013) João Conde et al.   BIOMATERIALS

In vivo tumor targeting via nanoparticle-mediated therapeutic siRNA coupled to inflammatory response in lung cancer mouse models

(2013) João Conde et al.   BIOMATERIALS

Tumour-associated macrophages and cancer

(2013) Jenny Cook et al.   CURRENT OPINION IN PHARMACOLOGY

The density of macrophages in colorectal cancer is inversely correlated to TGF-β1 expression and patients’ survival

(2013) Maya Gulubova et al.   JOURNAL OF MOLECULAR HISTOLOGY

Macrophage-Specific RNA Interference Targeting via “Click”, Mannosylated Polymeric Micelles

(2013) Shann S. Yu et al.   MOLECULAR PHARMACEUTICS

Delivery materials for siRNA therapeutics

(2013) Rosemary Kanasty et al.   NATURE MATERIALS

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

Targeted delivery of proapoptotic peptides to tumor-associated macrophages improves survival

(2013) M. Cieslewicz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design of Multifunctional Gold Nanoparticles for In Vitro and In Vivo Gene Silencing

(2012) João Conde et al.   ACS Nano

Gene Silencing by Gold Nanoshell-Mediated Delivery and Laser-Triggered Release of Antisense Oligonucleotide and siRNA

(2012) Ryan Huschka et al.   ACS Nano

Anti-tumour strategies aiming to target tumour-associated macrophages

(2012) Xiaoqiang Tang et al.   IMMUNOLOGY

Biomolecular coronas provide the biological identity of nanosized materials

(2012) Marco P. Monopoli et al.   Nature Nanotechnology

Topical delivery of siRNA-based spherical nucleic acid nanoparticle conjugates for gene regulation

(2012) Dan Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Bronchoalveolar lavage cell pattern from healthy human lung

(2011) M. Heron et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Therapeutic siRNA silencing in inflammatory monocytes in mice

(2011) Florian Leuschner et al.   NATURE BIOTECHNOLOGY

Current prospects for RNA interference-based therapies

(2011) Beverly L. Davidson et al.   NATURE REVIEWS GENETICS

Silencing or Stimulation? siRNA Delivery and the Immune System

(2011) Kathryn A. Whitehead et al.   Annual Review of Chemical and Biomolecular Engineering

Tumor Site-Specific Silencing of NF- B p65 by Targeted Hollow Gold Nanosphere-Mediated Photothermal Transfection

(2010) W. Lu et al.   CANCER RESEARCH

RNAi nanomedicines: challenges and opportunities within the immune system

(2010) Shiri Weinstein et al.   NANOTECHNOLOGY

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

(2010) Mark E. Davis et al.   NATURE

Nanoparticle-mediated delivery of siRNA targeting Parp1 extends survival of mice bearing tumors derived from Brca1-deficient ovarian cancer cells

(2010) M. S. Goldberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small silencing RNAs: State-of-the-art

(2009) Dirk Grimm   ADVANCED DRUG DELIVERY REVIEWS

Critical role of CD11b+ macrophages and VEGF in inflammatory lymphangiogenesis, antigen clearance, and inflammation resolution

(2009) R. P. Kataru et al.   BLOOD

Knocking down barriers: advances in siRNA delivery

(2009) Kathryn A. Whitehead et al.   NATURE REVIEWS DRUG DISCOVERY

Particle size-dependent organ distribution of gold nanoparticles after intravenous administration

(2008) Wim H. De Jong et al.   BIOMATERIALS

Sequence- and target-independent angiogenesis suppression by siRNA via TLR3

(2008) Mark E. Kleinman et al.   NATURE

Discovery and Development of Folic-Acid-Based Receptor Targeting for Imaging and Therapy of Cancer and Inflammatory Diseases

(2007) Philip S. Low et al.   ACCOUNTS OF CHEMICAL RESEARCH