Genomic profile of radiation-induced early-onset mouse B-cell lymphoma recapitulates features of Philadelphia chromosome-like acute lymphoblastic leukemia in humans

Interstitial chromosomal deletion of the tuberous sclerosis complex 2 locus is a signature for radiation‐associated renal tumors in Eker rats

(2020) Tatsuya Inoue et al.   CANCER SCIENCE

Early induction and increased risk of precursor B-cell neoplasms after exposure of infant or young-adult mice to ionizing radiation

(2020) Hirotaka Tachibana et al.   JOURNAL OF RADIATION RESEARCH

Mutational landscape of T-cell lymphoma in mice lacking the DNA mismatch repair gene Mlh1: no synergism with ionizing radiation

(2019) Kazuhiro Daino et al.   CARCINOGENESIS

How I diagnose and manage Philadelphia chromosome-like acute lymphoblastic leukemia

(2019) Avraham Frisch et al.   HAEMATOLOGICA

The Biology of B-Progenitor Acute Lymphoblastic Leukemia

(2019) Kathryn G. Roberts et al.   Cold Spring Harbor Perspectives in Medicine

The Role of the Pre-B Cell Receptor in B Cell Development, Repertoire Selection, and Tolerance

(2018) Thomas H. Winkler et al.   Frontiers in Immunology

Evaluation of automated Wes system as an analytical and characterization tool to support monoclonal antibody drug product development

(2017) Jinyu Wang et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

An Activating Janus Kinase-3 Mutation Is Associated with Cytotoxic T Lymphocyte Antigen-4-Dependent Immune Dysregulation Syndrome

(2017) Heiko Sic et al.   Frontiers in Immunology

LNK/SH2B3 regulates IL-7 receptor signaling in normal and malignant B-progenitors

(2016) Ying Cheng et al.   JOURNAL OF CLINICAL INVESTIGATION

Mutations or copy number losses of CD58 and TP53 genes in diffuse large B cell lymphoma are independent unfavorable prognostic factors

(2016) Yang Cao et al.   Oncotarget

PAX5 is a tumor suppressor in mouse mutagenesis models of acute lymphoblastic leukemia

(2015) J. Dang et al.   BLOOD

Infection Exposure Is a Causal Factor in B-cell Precursor Acute Lymphoblastic Leukemia as a Result of Pax5-Inherited Susceptibility

(2015) A. Martin-Lorenzo et al.   Cancer Discovery

Targetable Kinase-Activating Lesions in Ph-like Acute Lymphoblastic Leukemia

(2015) Kathryn G. Roberts et al.   NEW ENGLAND JOURNAL OF MEDICINE

JAK3 mutants transform hematopoietic cells through JAK1 activation, causing T-cell acute lymphoblastic leukemia in a mouse model

(2014) S. Degryse et al.   BLOOD

Cancer prevention by adult-onset calorie restriction after infant exposure to ionizing radiation in B6C3F1 male mice

(2014) Yi Shang et al.   INTERNATIONAL JOURNAL OF CANCER

The Interplay between Chromatin and Transcription Factor Networks during B Cell Development: Who Pulls the Trigger First?

(2014) Mohamed Amin Choukrallah et al.   Frontiers in Immunology

Sox4 Is Required for the Survival of Pro-B Cells

(2013) B. Sun et al.   JOURNAL OF IMMUNOLOGY

Acute lymphoblastic leukaemia

(2013) Hiroto Inaba et al.   LANCET

The Incidence of Leukemia, Lymphoma and Multiple Myeloma among Atomic Bomb Survivors: 1950–2001

(2013) Wan-Ling Hsu et al.   RADIATION RESEARCH

Mutational Processes Molding the Genomes of 21 Breast Cancers

(2012) Serena Nik-Zainal et al.   CELL

A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff

(2012) Pablo Cingolani et al.   FLY

VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing

(2012) D. C. Koboldt et al.   GENOME RESEARCH

PAX5/ETV6 alters the gene expression profile of precursor B cells with opposite dominant effect on endogenous PAX5

(2012) G Fazio et al.   LEUKEMIA

Role of the adaptor protein LNK in normal and malignant hematopoiesis

(2012) S Gery et al.   ONCOGENE

Control-FREEC: a tool for assessing copy number and allelic content using next-generation sequencing data

(2011) Valentina Boeva et al.   BIOINFORMATICS

Ebf1orPax5haploinsufficiency synergizes with STAT5 activation to initiate acute lymphoblastic leukemia

(2011) Lynn M. Heltemes-Harris et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Evaluation of PAX5 gene in the early stages of leukemic B cells in the childhood B cell acute lymphoblastic leukemia

(2011) Sinem Firtina et al.   LEUKEMIA RESEARCH

Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome

(2010) R. C. Harvey et al.   BLOOD

Genomic and gene expression signatures of radiation in medulloblastomas after low-dose irradiation in Ptch1 heterozygous mice

(2010) Yuka Ishida et al.   CARCINOGENESIS

PAX5 mutations occur frequently in adult B-cell progenitor acute lymphoblastic leukemia and PAX5 haploinsufficiency is associated with BCR-ABL1 and TCF3-PBX1 fusion genes: a GRAALL study

(2009) J Familiades et al.   LEUKEMIA

Biologic features and treatment outcome of secondary acute lymphoblastic leukemia—a review of 101 cases

(2008) R. Shivakumar et al.   ANNALS OF ONCOLOGY

Utilization of Pathway Signatures to Reveal Distinct Types of B Lymphoma in the E -myc Model and Human Diffuse Large B-Cell Lymphoma

(2008) S. Mori et al.   CANCER RESEARCH

Somatically acquiredJAK1mutations in adult acute lymphoblastic leukemia

(2008) Elisabetta Flex et al.   JOURNAL OF EXPERIMENTAL MEDICINE