Dopamine D3 receptor in the nucleus accumbens alleviates neuroinflammation in a mouse model of depressive-like behavior

Anti-depression effects of ketogenic diet are mediated via the restoration of microglial activation and neuronal excitability in the lateral habenula

(2020) Yan-Fei Guan et al.   BRAIN BEHAVIOR AND IMMUNITY

Neuroinflammation and depression: A review

(2020) Romain Troubat et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Optimization of adeno-associated viral vector-mediated transduction of the corticospinal tract: comparison of four promoters

(2020) Bart Nieuwenhuis et al.   GENE THERAPY

The Bidirectional Relationship of Depression and Inflammation: Double Trouble

(2020) Eléonore Beurel et al.   NEURON

Microglia in depression: current perspectives

(2020) Xiaoning Jia et al.   Science China-Life Sciences

Single-cell mass cytometry of microglia in major depressive disorder reveals a non-inflammatory phenotype with increased homeostatic marker expression

(2020) Chotima Böttcher et al.   Translational Psychiatry

Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer’s disease

(2020) Marta Olah et al.   Nature Communications

The behavioral sequelae of social defeat require microglia and are driven by oxidative stress in mice

(2019) Michael L. Lehmann et al.   JOURNAL OF NEUROSCIENCE

SRT2104 attenuates chronic unpredictable mild stress-induced depressive-like behaviors and imbalance between microglial M1 and M2 phenotypes in the mice

(2019) Chun-Mei Duan et al.   BEHAVIOURAL BRAIN RESEARCH

Microglial activation contributes to depressive-like behavior in dopamine D3 receptor knockout mice

(2019) Jing Wang et al.   BRAIN BEHAVIOR AND IMMUNITY

Dopamine receptor D3 signalling in astrocytes promotes neuroinflammation

(2019) Andro Montoya et al.   Journal of Neuroinflammation

Minocycline ameliorates depressive behaviors and neuro-immune dysfunction induced by chronic unpredictable mild stress in the rat

(2018) Cai Zhang et al.   BEHAVIOURAL BRAIN RESEARCH

The Dopamine Receptor D3 Regulates Lipopolysaccharide-Induced Depressive-Like Behavior in Mice

(2018) Jing Wang et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Nucleus accumbens inflammation mediates anxiodepressive behavior and compulsive sucrose seeking elicited by saturated dietary fat

(2018) Léa Décarie-Spain et al.   Molecular Metabolism

PI3K/AKT/GSK3β/CRMP-2-mediated neuroplasticity in depression induced by stress

(2018) Zuotian Wu et al.   NEUROREPORT

Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes

(2018) Timothy R. Hammond et al.   IMMUNITY

Depression

(2018) Gin S Malhi et al.   LANCET

Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing

(2018) Qingyun Li et al.   NEURON

Striatal dopamine D2/3 receptor-mediated neurotransmission in major depression: Implications for anhedonia, anxiety and treatment response

(2017) Marta Peciña et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

VGF function in depression and antidepressant efficacy

(2017) C Jiang et al.   MOLECULAR PSYCHIATRY

Social stress induces neurovascular pathology promoting depression

(2017) Caroline Menard et al.   NATURE NEUROSCIENCE

Microglia: An Interface between the Loss of Neuroplasticity and Depression

(2017) Gaurav Singhal et al.   Frontiers in Cellular Neuroscience

Liquiritigenin reverses depression-like behavior in unpredictable chronic mild stress-induced mice by regulating PI3K/Akt/mTOR mediated BDNF/TrkB pathway

(2016) Weiwei Tao et al.   BEHAVIOURAL BRAIN RESEARCH

A polarizing question: do M1 and M2 microglia exist?

(2016) Richard M Ransohoff   NATURE NEUROSCIENCE

Current drug treatments targeting dopamine D3 receptor

(2016) Gian Marco Leggio et al.   PHARMACOLOGY & THERAPEUTICS

Neurotransmitter receptors on microglia

(2016) Huan Liu et al.   JOURNAL OF INVESTIGATIVE MEDICINE

The Nucleus Accumbens: An Interface Between Cognition, Emotion, and Action

(2015) Stan B. Floresco   Annual Review of Psychology

Next generation transcriptomics and genomics elucidate biological complexity of microglia in health and disease

(2015) Paul D. Wes et al.   GLIA

Systemic inflammation and microglial activation: systematic review of animal experiments

(2015) Inge C.M. Hoogland et al.   Journal of Neuroinflammation

Inflammation of the Dental Pulp

(2015) Sang Hyuk Park et al.   MEDIATORS OF INFLAMMATION

Role of Translocator Protein Density, a Marker of Neuroinflammation, in the Brain During Major Depressive Episodes

(2015) Elaine Setiawan et al.   JAMA Psychiatry

Dopamine receptor D3 deficiency results in chronic depression and anxiety

(2014) Rodrigo Moraga-Amaro et al.   BEHAVIOURAL BRAIN RESEARCH

Evidence for increased microglial priming and macrophage recruitment in the dorsal anterior cingulate white matter of depressed suicides

(2014) Susana G. Torres-Platas et al.   BRAIN BEHAVIOR AND IMMUNITY

Differential roles of microglia and monocytes in the inflamed central nervous system

(2014) Ryo Yamasaki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Activation of Neuronal NMDA Receptors Triggers Transient ATP-Mediated Microglial Process Outgrowth

(2014) L. Dissing-Olesen et al.   JOURNAL OF NEUROSCIENCE

Dopamine D3 receptor as a new pharmacological target for the treatment of depression

(2013) Gian Marco Leggio et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Dopamine D3receptor activation promotes neural stem/progenitor cell proliferation through AKT and ERK1/2 pathways and expands type-B and -C cells in adult subventricular zone

(2013) Chu Lan Lao et al.   GLIA

Neuroinflammation and psychiatric illness

(2013) Souhel Najjar et al.   Journal of Neuroinflammation

The brain reward circuitry in mood disorders

(2013) Scott J. Russo et al.   NATURE REVIEWS NEUROSCIENCE

Is unpredictable chronic mild stress (UCMS) a reliable model to study depression-induced neuroinflammation?

(2012) Rai Khalid Farooq et al.   BEHAVIOURAL BRAIN RESEARCH

Medication discovery for addiction: Translating the dopamine D3 receptor hypothesis

(2012) Amy Hauck Newman et al.   BIOCHEMICAL PHARMACOLOGY

DRD3, but Not BDNF, Genotype Affects Treatment Response to Paroxetine in Major Depressive Disorder

(2012) Shoko Tsuchimine et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Specific Roles of Akt iso Forms in Apoptosis and Axon Growth Regulation in Neurons

(2012) Hector Diez et al.   PLoS One

Pre-synaptic dopamine D3 receptor mediates cocaine-induced structural plasticity in mesencephalic dopaminergic neurons via ERK and Akt pathways

(2011) Ginetta Collo et al.   JOURNAL OF NEUROCHEMISTRY

Microglial Morphology and Dynamic Behavior Is Regulated by Ionotropic Glutamatergic and GABAergic Neurotransmission

(2011) Aurora M. Fontainhas et al.   PLoS One

Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders

(2010) Rainer Rupprecht et al.   NATURE REVIEWS DRUG DISCOVERY

Inflammation Causes Mood Changes Through Alterations in Subgenual Cingulate Activity and Mesolimbic Connectivity

(2009) Neil A. Harrison et al.   BIOLOGICAL PSYCHIATRY

Behavioral profile of P2X7 receptor knockout mice in animal models of depression and anxiety: Relevance for neuropsychiatric disorders

(2008) Ana M. Basso et al.   BEHAVIOURAL BRAIN RESEARCH

AKT Signaling within the Ventral Tegmental Area Regulates Cellular and Behavioral Responses to Stressful Stimuli

(2008) Vaishnav Krishnan et al.   BIOLOGICAL PSYCHIATRY

The molecular neurobiology of depression

(2008) Vaishnav Krishnan et al.   NATURE