Specific Roles of Akt iso Forms in Apoptosis and Axon Growth Regulation in Neurons

Nonredundant Functions for Akt Isoforms in Astrocyte Growth and Gliomagenesis in an Orthotopic Transplantation Model

(2011) R. Endersby et al.   CANCER RESEARCH

The Akt kinases: Isoform specificity in metabolism and cancer

(2011) Eva Gonzalez et al.   CELL CYCLE

Promiscuous affairs of PKB/AKT isoforms in metabolism

(2011) Simon M. Schultze et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Functions and regulation of the 70kDa ribosomal S6 kinases

(2010) Tim R. Fenton et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Mammalian Target of Rapamycin (mTOR): Conducting the Cellular Signaling Symphony

(2010) Kathryn G. Foster et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Akt isoforms are present at distinct subcellular locations

(2009) Stacey A. Santi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Glycogen synthase kinase 3: more than a namesake

(2009) Geetha Vani Rayasam et al.   BRITISH JOURNAL OF PHARMACOLOGY

Initiation of neuronal differentiation requires PI3-kinase/TOR signalling in the vertebrate neural tube

(2009) Katherine J. Fishwick et al.   DEVELOPMENTAL BIOLOGY

Cell type specificity of PI3K signaling in Pdk1- and Pten-deficient brains

(2009) N. Chalhoub et al.   GENES & DEVELOPMENT

Specification of Neuronal Polarity Regulated by Local Translation of CRMP2 and Tau via the mTOR-p70S6K Pathway

(2009) Tsuyoshi Morita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The nuts and bolts of AGC protein kinases

(2009) Laura R. Pearce et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Role of a Novel PH-Kinase Domain Interface in PKB/Akt Regulation: Structural Mechanism for Allosteric Inhibition

(2009) Véronique Calleja et al.   PLOS BIOLOGY

mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)

(2008) Juan M. García-Martínez et al.   BIOCHEMICAL JOURNAL

AKT3 as a candidate gene for corpus callosum anomalies in patients with 1q44 deletions

(2008) Martin Poot et al.   European Journal of Medical Genetics

The Tsc1-Tsc2 complex influences neuronal polarity by modulating TORC1 activity and SAD levels

(2008) J. Wildonger et al.   GENES & DEVELOPMENT

Tuberous sclerosis complex proteins control axon formation

(2008) Y.-J. Choi et al.   GENES & DEVELOPMENT

Phosphorylation of mutant huntingtin at S421 restores anterograde and retrograde transport in neurons

(2008) Diana Zala et al.   HUMAN MOLECULAR GENETICS

Rheb and mTOR Regulate Neuronal Polarity through Rap1B

(2008) Ying-Hua Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian target of rapamycin (mTOR) is involved in the neuronal differentiation of neural progenitors induced by insulin

(2008) Jin Han et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Phosphorylation of huntingtin reduces the accumulation of its nuclear fragments

(2008) Simon C. Warby et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Promoting Axon Regeneration in the Adult CNS by Modulation of the PTEN/mTOR Pathway

(2008) K. K. Park et al.   SCIENCE

PKB and the mitochondria: AKTing on apoptosis

(2007) Arnaud Parcellier et al.   CELLULAR SIGNALLING

A 6.9Mb 1qter deletion/4.4Mb 18pter duplication in a boy with extreme microcephaly with simplified gyral pattern, vermis hypoplasia and corpus callosum agenesis

(2007) Joris Andrieux et al.   European Journal of Medical Genetics