Dietary lignans, plasma enterolactone levels, and metabolic risk in men: exploring the role of the gut microbiome

Gut microbiota–derived metabolites and risk of coronary artery disease: a prospective study among US men and women

(2021) Gang Liu et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Serum metabolites reflecting gut microbiome alpha diversity predict type 2 diabetes

(2020) Cristina Menni et al.   Gut Microbes

Factors Explaining Interpersonal Variation in Plasma Enterolactone Concentrations in Humans

(2019) Elin Hålldin et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Microbiome–metabolomics reveals gut microbiota associated with glycine-conjugated metabolites and polyamine metabolism in chronic kidney disease

(2019) Ya-Long Feng et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Genetic basis for the cooperative bioactivation of plant lignans by Eggerthella lenta and other human gut bacteria

(2019) Elizabeth N. Bess et al.   Nature Microbiology

Glycoside‐specific glycosyltransferases catalyze regio‐selective sequential glucosylations for a sesame lignan, sesaminol triglucoside

(2019) Eiichiro Ono et al.   PLANT JOURNAL

OUP accepted manuscript

(2018)   AMERICAN JOURNAL OF CLINICAL NUTRITION

Metabolic Predictors of Incident Coronary Heart Disease in Women

(2018) Nina P. Paynter et al.   CIRCULATION

Metatranscriptome of human faecal microbial communities in a cohort of adult men

(2018) Galeb S. Abu-Ali et al.   Nature Microbiology

Stability of the human faecal microbiome in a cohort of adult men

(2018) Raaj S. Mehta et al.   Nature Microbiology

Faecalibacterium prausnitzii: from microbiology to diagnostics and prognostics

(2017) Mireia Lopez-Siles et al.   ISME Journal

Plasma metabolite abundances are associated with urinary enterolactone excretion in healthy participants on controlled diets

(2017) Fayth L. Miles et al.   Food & Function

Hippurate as a metabolomic marker of gut microbiome diversity: Modulation by diet and relationship to metabolic syndrome

(2017) Tess Pallister et al.   Scientific Reports

Associations of anthropometric markers with serum metabolites using a targeted metabolomics approach: results of the EPIC-potsdam study

(2016) U Bachlechner et al.   Nutrition & Diabetes

Urinary enterolactone is associated with obesity and metabolic alteration in men in the US National Health and Nutrition Examination Survey 2001–10

(2015) Cheng Xu et al.   BRITISH JOURNAL OF NUTRITION

Gut metabolites and bacterial community networks during a pilot intervention study with flaxseeds in healthy adult men

(2015) Ilias Lagkouvardos et al.   MOLECULAR NUTRITION & FOOD RESEARCH

MetaPhlAn2 for enhanced metagenomic taxonomic profiling

(2015) Duy Tin Truong et al.   NATURE METHODS

The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases

(2015) Ron Caspi et al.   NUCLEIC ACIDS RESEARCH

Enterolignan-Producing Phenotypes Are Associated with Increased Gut Microbial Diversity and Altered Composition in Premenopausal Women in the United States

(2014) M. A. J. Hullar et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Gut Microbiota Metabolites of Dietary Lignans and Risk of Type 2 Diabetes: A Prospective Investigation in Two Cohorts of U.S. Women

(2014) Qi Sun et al.   DIABETES CARE

Sex Hormone-Binding Globulin Gene Expression and Insulin Resistance

(2014) Stephen J. Winters et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The Same Microbiota and a Potentially Discriminant Metabolome in the Saliva of Omnivore, Ovo-Lacto-Vegetarian and Vegan Individuals

(2014) Francesca De Filippis et al.   PLoS One

Flaxseed (Linum usitatissimum L.) extract as well as (+)-secoisolariciresinol diglucoside and its mammalian derivatives are potent inhibitors of α-amylase activity

(2013) Christophe Hano et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Dietary Sesame Seed and Its Lignan, Sesamin, Increase Tocopherol and Phylloquinone Concentrations in Male Rats

(2013) Fumiaki Hanzawa et al.   JOURNAL OF NUTRITION

Matairesinol inhibits angiogenesis via suppression of mitochondrial reactive oxygen species

(2012) Boram Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mammary gene expression and activity of antioxidant enzymes and concentration of the mammalian lignan enterolactone in milk and plasma of dairy cows fed flax lignans and infused with flax oil in the abomasum

(2012) Cristiano Côrtes et al.   BRITISH JOURNAL OF NUTRITION

Urinary Enterolignan Concentrations Are Positively Associated with Serum HDL Cholesterol and Negatively Associated with Serum Triglycerides in U.S. Adults

(2012) José L. Peñalvo et al.   JOURNAL OF NUTRITION

Among Plant Lignans, Pinoresinol Has the Strongest Antiinflammatory Properties in Human Intestinal Caco-2 Cells

(2012) Alexandrine During et al.   JOURNAL OF NUTRITION

Metabolic Reconstruction for Metagenomic Data and Its Application to the Human Microbiome

(2012) Sahar Abubucker et al.   PLoS Computational Biology

Body Size in Early Life and Adult Levels of Insulin-like Growth Factor 1 and Insulin-like Growth Factor Binding Protein 3

(2011) E. M. Poole et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Role of bifidobacteria in the activation of the lignan secoisolariciresinol diglucoside

(2011) Lucia Roncaglia et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Human Intestinal Bacterium, Strain END-2 Is Responsible for Demethylation as Well as Lactonization during Plant Lignan Metabolism

(2010) Jong-Sik Jin et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Association between Faecalibacterium prausnitzii and dietary fibre in colonic fermentation in healthy human subjects

(2010) Robin F. J. Benus et al.   BRITISH JOURNAL OF NUTRITION

Association Between a Literature-Based Genetic Risk Score and Cardiovascular Events in Women

(2010) Nina P. Paynter   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Meta-analysis of the effects of flaxseed interventions on blood lipids

(2009) An Pan et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

A randomized controlled trial of the effects of flaxseed lignan complex on metabolic syndrome composite score and bone mineral in older adults

(2009) Stephen M. Cornish et al.   Applied Physiology Nutrition and Metabolism

Further Studies on a Human Intestinal BacteriumRuminococcussp. END-1 for Transformation of Plant Lignans to Mammalian Lignans

(2009) Jong-Sik Jin et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Sex Hormone–Binding Globulin and Risk of Type 2 Diabetes in Women and Men

(2009) Eric L. Ding et al.   NEW ENGLAND JOURNAL OF MEDICINE

Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites

(2009) W. R. Wikoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolism of the Lignan Macromolecule into Enterolignans in the Gastrointestinal Lumen As Determined in the Simulator of the Human Intestinal Microbial Ecosystem

(2008) Ellen Eeckhaut et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Sequential glucosylation of a furofuran lignan, (+)-sesaminol, by Sesamum indicum UGT71A9 and UGT94D1 glucosyltransferases

(2008) Akio Noguchi et al.   PLANT JOURNAL

Regression of hypercholesterolemic atherosclerosis in rabbits by secoisolariciresinol diglucoside isolated from flaxseed

(2007) Kailash Prasad   ATHEROSCLEROSIS