Novel 18β-glycyrrhetinic acid derivatives as a Two-in-One agent with potent antimicrobial and anti-inflammatory activity

The in vitro and in vivo study of oleanolic acid indole derivatives as novel anti-inflammatory agents: Synthesis, biological evaluation, and mechanistic analysis

(2021) Jingwei Jin et al.   BIOORGANIC CHEMISTRY

Preparation of a water soluble aminated β‐1, 3‐D ‐glucan for gene carrier: The in vitro study of the anti‐inflammatory activity and transfection efficiency

(2021) Jing Wei Jin et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Glycyrrhetinic Acid Improves Insulin-Response Pathway by Regulating the Balance between the Ras/MAPK and PI3K/Akt Pathways

(2019) Yuan Zhang et al.   Nutrients

Antibiotic adjuvants: an alternative approach to overcome multi-drug resistant Gram-negative bacteria

(2019) Yuan Liu et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Modification, Antitumor Activity, and Targeted PPARγ Study of 18β-Glycyrrhetinic Acid, an Important Active Ingredient of Licorice

(2019) Juan Sun et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Oleanolic Acid Exerts a Neuroprotective Effect Against Microglial Cell Activation by Modulating Cytokine Release and Antioxidant Defense Systems

(2019) José M. Castellano et al.   Biomolecules

The dietary triterpenoid 18α–Glycyrrhetinic acid protects from MMC-induced genotoxicity through the ERK/Nrf2 pathway

(2019) Maria Lefaki et al.   Redox Biology

18β-Glycyrrhetinic acid mitigates radiation-induced skin damage via NADPH oxidase/ROS/p38MAPK and NF-κB pathways

(2018) Li Su et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Anti-inflammatory Activity of 8-Hydroxydaidzein in LPS-Stimulated BV2 Microglial Cells via Activation of Nrf2-Antioxidant and Attenuation of Akt/NF-κB-Inflammatory Signaling Pathways, as Well As Inhibition of COX-2 Activity

(2018) Pei-Shan Wu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Glycyrrhizic acid from licorice down-regulates inflammatory responses via blocking MAPKs and PI3K/Akt-dependent NF-κB signalling pathways in TPA-induced skin inflammation

(2018) Wenfeng Liu et al.   MedChemComm

18β-Glycyrrhetinic Acid Inhibits Osteoclastogenesis In Vivo and In Vitro by Blocking RANKL-Mediated RANK–TRAF6 Interactions and NF-κB and MAPK Signaling Pathways

(2018) Xiao Chen et al.   Frontiers in Pharmacology

Novel unsaturated glycyrrhetic acids derivatives: Design, synthesis and anti-inflammatory activity

(2017) Bo Li et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

An Overview of Structurally Modified Glycyrrhetinic Acid Derivatives as Antitumor Agents

(2017) Bing Xu et al.   MOLECULES

The structural modification of natural products for novel drug discovery

(2016) Hong Yao et al.   Expert Opinion on Drug Discovery

Protective Effects of Glycyrrhizic Acid and 18β-Glycyrrhetinic Acid against Cisplatin-Induced Nephrotoxicity in BALB/c Mice

(2015) Chi-Hao Wu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A protective mechanism of licorice (Glycyrrhiza uralensis): Isoliquiritigenin stimulates detoxification system via Nrf2 activation

(2015) Hui Gong et al.   JOURNAL OF ETHNOPHARMACOLOGY

Multi-functional Liposomes Enhancing Target and Antibacterial Immunity for Antimicrobial and Anti-Biofilm Against Methicillin-Resistant Staphylococcus aureus

(2015) Yansha Meng et al.   PHARMACEUTICAL RESEARCH

Synthesis of Novel Heterocyclic Ring-Fused 18β-Glycyrrhetinic Acid Derivatives with Antitumor and Antimetastatic Activity

(2014) Cheng Gao et al.   Chemical Biology & Drug Design

Glycyrrhetinic Acid Suppressed NF-κB Activation in TNF-α-Induced Hepatocytes

(2014) Hong-Jhang Chen et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Comparaison de la sensibilité aux antibiotiques de Corynebacterium diphtheriae par les méthodes de dilution en bouillon et de diffusion (E-test et disques)

(2014) N. Benamrouche et al.   MEDECINE ET MALADIES INFECTIEUSES

Discovery of a Potential Anti-Inflammatory Agent: 3-Oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile

(2013) Ran You et al.   JOURNAL OF MEDICINAL CHEMISTRY

Inhibition of inflammatory mediators contributes to the anti-inflammatory activity of KYKZL-1 via MAPK and NF-κB pathway

(2013) Guang-Lin Xu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Naturally derived anti-inflammatory compounds from Chinese medicinal plants

(2012) Qiuhong Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Chitosan oligosaccharides inhibit LPS-induced over-expression of IL-6 and TNF-α in RAW264.7 macrophage cells through blockade of mitogen-activated protein kinase (MAPK) and PI3K/Akt signaling pathways

(2011) Pan Ma et al.   CARBOHYDRATE POLYMERS

Glycyrrhizic Acid and 18β-Glycyrrhetinic Acid Modulate Lipopolysaccharide-Induced Inflammatory Response by Suppression of NF-κB through PI3K p110δ and p110γ Inhibitions

(2011) Chung-Yi Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Glycyrrhetinic acid inhibits ICAM-1 expression via blocking JNK and NF-κB pathways in TNF-α-activated endothelial cells

(2010) Ying-ling Chang et al.   ACTA PHARMACOLOGICA SINICA

Nonresolving Inflammation

(2010) Carl Nathan et al.   CELL

Inflammation 2010: New Adventures of an Old Flame

(2010) Ruslan Medzhitov   CELL

Novel effects of glycyrrhetinic acid on the central nervous system tumorigenic progenitor cells: Induction of actin disruption and tumor cell-selective toxicity

(2010) Hideaki Yamaguchi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Glycyrrhizic Acid and 18β-Glycyrrhetinic Acid Inhibit Inflammation via PI3K/Akt/GSK3β Signaling and Glucocorticoid Receptor Activation

(2010) Tzu-Chien Kao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

18β-Glycyrrhetinic Acid Ameliorates Acute Propionibacterium acnes-induced Liver Injury through Inhibition of Macrophage Inflammatory Protein-1α

(2009) Yichuan Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recent developments in anti-inflammatory natural products

(2009) Raju Gautam et al.   MEDICINAL RESEARCH REVIEWS

Comparison of Disk Diffusion and Agar Dilution Methods for Erythromycin, Ciprofloxacin, and Tetracycline Susceptibility Testing of Campylobacter coli and for Tetracycline Susceptibility Testing of Campylobacter jejuni subsp. jejuni

(2008) C. Gaudreau et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE

Review of Pharmacological Effects ofGlycyrrhiza sp. and its Bioactive Compounds

(2008) Marjan Nassiri Asl et al.   PHYTOTHERAPY RESEARCH

Synthesis and biological evaluation of some thiazolyl and thiadiazolyl derivatives of 1H-pyrazole as anti-inflammatory antimicrobial agents

(2007) Adnan A. Bekhit et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Antiviral effects ofGlycyrrhiza species

(2007) Cristina Fiore et al.   PHYTOTHERAPY RESEARCH