Pyrroloquinoline quinone ameliorates renal fibrosis in diabetic nephropathy by inhibiting the pyroptosis pathway in C57BL/6 mice and human kidney 2 cells

Global and regional estimates and projections of diabetes-related health expenditure: results from the International Diabetes Federation Diabetes Atlas, 9th edition

(2020) Rhys Williams et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Polyphyllin VI Induces Caspase-1-Mediated Pyroptosis via the Induction of ROS/NF-κB/NLRP3/GSDMD Signal Axis in Non-Small Cell Lung Cancer

(2020) Jin-Feng Teng et al.   Cancers

Dendropanax morbifera Protects against Renal Fibrosis in Streptozotocin-Induced Diabetic Rats

(2020) Richa Sachan et al.   Antioxidants

The Hypoglycemic and Renal Protection Properties of Crocin via Oxidative Stress-Regulated NF-κB Signaling in db/db Mice

(2020) Ye Qiu et al.   Frontiers in Pharmacology

Pyrroloquinoline quinone can prevent chronic heart failure by regulating mitochondrial function

(2020) Xuan Xu et al.   Cardiovascular Diagnosis and Therapy

Ameliorate effect of pyrroloquinoline quinone against cyclophosphamide-induced nephrotoxicity by activating the Nrf2 pathway and inhibiting the NLRP3 pathway

(2020) Xinhui Lin et al.   LIFE SCIENCES

PGRN acts as a novel regulator of mitochondrial homeostasis by facilitating mitophagy and mitochondrial biogenesis to prevent podocyte injury in diabetic nephropathy

(2019) Di Zhou et al.   Cell Death & Disease

PQQ ameliorates skeletal muscle atrophy, mitophagy and fiber type transition induced by denervation via inhibition of the inflammatory signaling pathways

(2019) Wenjing Ma et al.   Annals of Translational Medicine

Pyrroloquinoline quinine protects HK-2 cells against high glucose-induced oxidative stress and apoptosis through Sirt3 and PI3K/Akt/FoxO3a signaling pathway

(2018) Ziqiang Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Huangkui capsule alleviates renal tubular epithelial-mesenchymal transition in diabetic nephropathy via inhibiting NLRP3 inflammasome activation and TLR4/NF-κB signaling

(2018) Wenbei Han et al.   PHYTOMEDICINE

Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases

(2017) Si Ming Man et al.   IMMUNOLOGICAL REVIEWS

Pyrroloquinoline quinone ameliorates oxidative stress and lipid peroxidation in the brain of streptozotocin-induced diabetic mice

(2015) Narendra Kumar et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Pyrroloquinoline Quinone Decelerates Rheumatoid Arthritis Progression by Inhibiting Inflammatory Responses and Joint Destruction via Modulating NF-κB and MAPK Pathways

(2015) Zhongbing Liu et al.   INFLAMMATION

Pyrroloquinoline-Quinone Suppresses Liver Fibrogenesis in Mice

(2015) Dongwei Jia et al.   PLoS One

Nlrp3 Inflammasome Activation in Type 2 Diabetes: Is It Clinically Relevant?

(2012) Vishwa Deep Dixit   DIABETES

Signaling Mechanisms in the Regulation of Renal Matrix Metabolism in Diabetes

(2012) Meenalakshmi M. Mariappan   Experimental Diabetes Research

Inflammation-Induced Endothelial-to-Mesenchymal Transition

(2011) Florian Rieder et al.   AMERICAN JOURNAL OF PATHOLOGY

The NLRP3 Inflammasome: A Sensor for Metabolic Danger?

(2010) K. Schroder et al.   SCIENCE

IL-18 neutralization ameliorates obstruction-induced epithelial–mesenchymal transition and renal fibrosis

(2009) Ahmad H. Bani-Hani et al.   KIDNEY INTERNATIONAL