Multifunctional elastomer cardiac patches for preventing left ventricle remodeling after myocardial infarction in vivo

Strontium ions protect hearts against myocardial ischemia/reperfusion injury

(2021) Min Xing et al.   Science Advances

Minimally invasive delivery of therapeutic agents by hydrogel injection into the pericardial cavity for cardiac repair

(2021) Dashuai Zhu et al.   Nature Communications

Injectable hydrogel with MSNs/microRNA-21-5p delivery enables both immunomodification and enhanced angiogenesis for myocardial infarction therapy in pigs

(2021) Yan Li et al.   Science Advances

A perfusable, multifunctional epicardial device improves cardiac function and tissue repair

(2021) Shixing Huang et al.   NATURE MEDICINE

Exosome-eluting stents for vascular healing after ischaemic injury

(2021) Shiqi Hu et al.   Nature Biomedical Engineering

Fatigue-resistant polyurethane elastomer composites

(2021) Guogao Zhang et al.   Extreme Mechanics Letters

Current advances in biodegradable synthetic polymer based cardiac patches

(2020) Sara McMahan et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Platelet-derived growth factor-AB improves scar mechanics and vascularity after myocardial infarction

(2020) Sujitha Thavapalachandran et al.   Science Translational Medicine

Myocardial injection of a thermoresponsive hydrogel with reactive oxygen species scavenger properties improves border zone contractility

(2020) Kimberly A. Spaulding et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

An off-the-shelf artificial cardiac patch improves cardiac repair after myocardial infarction in rats and pigs

(2020) Ke Huang et al.   Science Translational Medicine

Multifunctional 3D‐Printed Patches for Long‐Term Drug Release Therapies after Myocardial Infarction

(2020) Rubina Ajdary et al.   ADVANCED FUNCTIONAL MATERIALS

Microneedle-mediated gene delivery for the treatment of ischemic myocardial disease

(2020) Hongpeng Shi et al.   Science Advances

Multiple H‐Bonding Chain Extender‐Based Ultrastiff Thermoplastic Polyurethanes with Autonomous Self‐Healability, Solvent‐Free Adhesiveness, and AIE Fluorescence

(2020) Yuan Yao et al.   ADVANCED FUNCTIONAL MATERIALS

Transplanted microvessels improve pluripotent stem cell–derived cardiomyocyte engraftment and cardiac function after infarction in rats

(2020) Xuetao Sun et al.   Science Translational Medicine

Patterned human microvascular grafts enable rapid vascularization and increase perfusion in infarcted rat hearts

(2019) Meredith A. Redd et al.   Nature Communications

Immune cells as targets for cardioprotection: new players and novel therapeutic opportunities

(2019) Ioanna Andreadou et al.   CARDIOVASCULAR RESEARCH

Reactive Oxygen Species (ROS)-Based Nanomedicine

(2019) Bowen Yang et al.   CHEMICAL REVIEWS

A viscoelastic adhesive epicardial patch for treating myocardial infarction

(2019) Xiao Lin et al.   Nature Biomedical Engineering

Pro-Angiogenic Macrophage Phenotype to Promote Myocardial Repair

(2019) Bartolo Ferraro et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Dual stem cell therapy synergistically improves cardiac function and vascular regeneration following myocardial infarction

(2019) Soon-Jung Park et al.   Nature Communications

In situ pPy-modification of chitosan porous membrane from mussel shell as a cardiac patch to repair myocardial infarction

(2019) Xiaoping Song et al.   Applied Materials Today

Epicardial cells derived from human embryonic stem cells augment cardiomyocyte-driven heart regeneration

(2019) Johannes Bargehr et al.   NATURE BIOTECHNOLOGY

Injectable Citrate-Based Hydrogel as an Angiogenic Biomaterial Improves Cardiac Repair after Myocardial Infarction

(2019) Zhize Yuan et al.   ACS Applied Materials & Interfaces

ROS-responsive polyurethane fibrous patches loaded with methylprednisolone (MP) for restoring structures and functions of infarcted myocardium in vivo

(2019) Yuejun Yao et al.   BIOMATERIALS

Engineering Bioinspired Antioxidant Materials Promoting Cardiomyocyte Functionality and Maturation for Tissue Engineering Application

(2018) Parvaiz A. Shiekh et al.   ACS Applied Materials & Interfaces

Dual Roles of Graphene Oxide To Attenuate Inflammation and Elicit Timely Polarization of Macrophage Phenotypes for Cardiac Repair

(2018) Jin Han et al.   ACS Nano

Paintable and Rapidly Bondable Conductive Hydrogels as Therapeutic Cardiac Patches

(2018) Shuang Liang et al.   ADVANCED MATERIALS

Reactive oxygen species scavenging with a biodegradable, thermally responsive hydrogel compatible with soft tissue injection

(2018) Yang Zhu et al.   BIOMATERIALS

Anti-inflammatory therapies in myocardial infarction: failures, hopes and challenges

(2018) Shuaibo Huang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Targeting protein and peptide therapeutics to the heart via tannic acid modification

(2018) Mikyung Shin et al.   Nature Biomedical Engineering

Probing the Migration of Free Radicals in Solid and Liquid Media via Cr(VI) Reduction by High-Energy Electron Beam Irradiation

(2018) Jie Han et al.   Scientific Reports

Cardiovascular disease models: A game changing paradigm in drug discovery and screening

(2018) Houman Savoji et al.   BIOMATERIALS

Flexible shape-memory scaffold for minimally invasive delivery of functional tissues

(2017) Miles Montgomery et al.   NATURE MATERIALS

Bi-layered polyurethane – Extracellular matrix cardiac patch improves ischemic ventricular wall remodeling in a rat model

(2016) Antonio D'Amore et al.   BIOMATERIALS

Macrophages in Tissue Repair, Regeneration, and Fibrosis

(2016) Thomas A. Wynn et al.   IMMUNITY

Inflammatory processes in cardiovascular disease: a route to targeted therapies

(2016) Neil Ruparelia et al.   Nature Reviews Cardiology

MicroRNAs and Cardiac Regeneration

(2015) C. P. Hodgkinson et al.   CIRCULATION RESEARCH

Synthesis and characterization of biodegradable polyurethanes with unsaturated carbon bonds based on poly(propylene fumarate)

(2015) Bin Hu et al.   JOURNAL OF APPLIED POLYMER SCIENCE

Heart regeneration after myocardial infarction using synthetic biomaterials

(2015) S. Pascual-Gil et al.   JOURNAL OF CONTROLLED RELEASE

A porous tissue engineering scaffold selectively degraded by cell-generated reactive oxygen species

(2014) John R. Martin et al.   BIOMATERIALS

The effect of polymer degradation time on functional outcomes of temporary elastic patch support in ischemic cardiomyopathy

(2013) Ryotaro Hashizume et al.   BIOMATERIALS

The effect of controlled expression of VEGF by transduced myoblasts in a cardiac patch on vascularization in a mouse model of myocardial infarction

(2012) Anna Marsano et al.   BIOMATERIALS

Rosuvastatin promotes angiogenesis and reverses isoproterenol-induced acute myocardial infarction in rats: Role of iNOS and VEGF

(2012) Sawsan A. Zaitone et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Biodegradable elastic patch plasty ameliorates left ventricular adverse remodeling after ischemia–reperfusion injury: A preclinical study of a porous polyurethane material in a porcine model

(2012) Ryotaro Hashizume et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Passive Stiffness of Myocardium From Congenital Heart Disease and Implications for Diastole

(2010) Rajiv R. Chaturvedi et al.   CIRCULATION

From endoplasmic-reticulum stress to the inflammatory response

(2008) Kezhong Zhang et al.   NATURE