New appreciation for an old pathway: the Lands Cycle moves into new arenas in health and disease

Oxylipin metabolism is controlled by mitochondrial β-oxidation during bacterial inflammation

(2022) Mariya Misheva et al.   Nature Communications

Update and nomenclature proposal for mammalian lysophospholipid acyltransferases, which create membrane phospholipid diversity

(2021) William J. Valentine et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MBOAT7 down-regulation by genetic and environmental factors predisposes to MAFLD

(2020) Marica Meroni et al.   EBioMedicine

rs641738C>T near MBOAT7 is associated with liver fat, ALT, and fibrosis in NAFLD: a meta-analysis

(2020) Kevin Teo et al.   JOURNAL OF HEPATOLOGY

Enzymatically oxidized phospholipids assume center stage as essential regulators of innate immunity and cell death

(2019) Valerie B. O’Donnell et al.   Science Signaling

LPCAT1 promotes brain metastasis of lung adenocarcinoma by up-regulating PI3K/AKT/MYC pathway

(2019) Chunhua Wei et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Phospholipid membranes drive abdominal aortic aneurysm development through stimulating coagulation factor activity

(2019) Keith Allen-Redpath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling

(2019) Junfeng Bi et al.   Cell Metabolism

Multiplexed and single cell tracing of lipid metabolism

(2019) Christoph Thiele et al.   NATURE METHODS

Lysophosphatidylcholine acyltransferase 2-mediated lipid droplet production supports colorectal cancer chemoresistance

(2018) Alexia Karen Cotte et al.   Nature Communications

Phospholipid Remodeling in Physiology and Disease

(2018) Bo Wang et al.   Annual Review of Physiology

Lysophospholipases Cooperate to Mediate Lipid Homeostasis and Lysophospholipid Signaling

(2018) James A. Wepy et al.   JOURNAL OF LIPID RESEARCH

Relief from neuropathic pain by blocking of the platelet-activating factor–pain loop

(2017) Hideo Shindou et al.   FASEB JOURNAL

Lysophospholipid-Related Diseases and PPARγ Signaling Pathway

(2017) Tamotsu Tsukahara et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease

(2017) Stefan Uderhardt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Long-chain acyl-CoA synthetase isoforms differ in preferences for eicosanoid species and long-chain fatty acids

(2017) Eric L. Klett et al.   JOURNAL OF LIPID RESEARCH

Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis

(2017) Sarah N. Lauder et al.   Science Signaling

Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis

(2017) Sarah N. Lauder et al.   Science Signaling

Mapping the Human Platelet Lipidome Reveals Cytosolic Phospholipase A2 as a Regulator of Mitochondrial Bioenergetics during Activation

(2016) David A. Slatter et al.   Cell Metabolism

Lysophospholipids and their G protein-coupled receptors in atherosclerosis

(2016) Rong-Shan Li   Frontiers in Bioscience-Landmark

The MBOAT7-TMC4 Variant rs641738 Increases Risk of Nonalcoholic Fatty Liver Disease in Individuals of European Descent

(2016) Rosellina Margherita Mancina et al.   GASTROENTEROLOGY

An epigenome-wide association study of total serum immunoglobulin E concentration

(2015) Liming Liang et al.   NATURE

Lpcat3-dependent production of arachidonoyl phospholipids is a key determinant of triglyceride secretion

(2015) Xin Rong et al.   eLife

Fatty acid remodeling by LPCAT3 enriches arachidonate in phospholipid membranes and regulates triglyceride transport

(2015) Tomomi Hashidate-Yoshida et al.   eLife

Acyl-CoA Metabolism and Partitioning

(2014) Trisha J. Grevengoed et al.   Annual Review of Nutrition

Lysophospholipid Acyltransferases Mediate Phosphatidylcholine Diversification to Achieve the Physical Properties Required In Vivo

(2014) Takeshi Harayama et al.   Cell Metabolism

Lipid interactions during virus entry and infection

(2014) Michela Mazzon et al.   CELLULAR MICROBIOLOGY

Measurement of lysophospholipid acyltransferase activities using substrate competition

(2014) Sarah A. Martin et al.   JOURNAL OF LIPID RESEARCH

Generation of membrane diversity by lysophospholipid acyltransferases

(2013) H. Shindou et al.   JOURNAL OF BIOCHEMISTRY

Novel Keto-phospholipids Are Generated by Monocytes and Macrophages, Detected in Cystic Fibrosis, and Activate Peroxisome Proliferator-activated Receptor-γ

(2012) Victoria J. Hammond et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cholesteryl ester acyl oxidation and remodeling in murine macrophages: formation of oxidized phosphatidylcholine

(2012) Patrick M. Hutchins et al.   JOURNAL OF LIPID RESEARCH

LPIAT1 regulates arachidonic acid content in phosphatidylinositol and is required for cortical lamination in mice

(2012) Hyeon-Cheol Lee et al.   MOLECULAR BIOLOGY OF THE CELL

Lipidomics of Alzheimer's disease: current status

(2012) Paul L Wood   Alzheimers Research & Therapy

Polyunsaturated fatty acids are incorporated into maturating male mouse germ cells by lysophosphatidic acid acyltransferase 3

(2011) Andreas Koeberle et al.   FASEB JOURNAL

Lysophosphatidylcholines activate G2A inducing Gαi-1-/Gαq/11- Ca2+flux, Gβγ-Hck activation and clathrin/β-arrestin-1/GRK6 recruitment in PMNs

(2010) Samina Y. Khan et al.   BIOCHEMICAL JOURNAL

Acyl-coenzyme A synthetases in metabolic control

(2010) Jessica M Ellis et al.   CURRENT OPINION IN LIPIDOLOGY

Phospholipid-esterified Eicosanoids Are Generated in Agonist-activated Human Platelets and Enhance Tissue Factor-dependent Thrombin Generation

(2010) Christopher P. Thomas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LPCAT1 regulates surfactant phospholipid synthesis and is required for transitioning to air breathing in mice

(2010) James P. Bridges et al.   JOURNAL OF CLINICAL INVESTIGATION

Lysophosphatidylcholine Increases Neutrophil Bactericidal Activity by Enhancement of Azurophil Granule-Phagosome Fusion via Glycine{middle dot}GlyR 2/TRPM2/p38 MAPK Signaling

(2010) C. W. Hong et al.   JOURNAL OF IMMUNOLOGY

Identification of membrane O-acyltransferase family motifs

(2009) Hideo Shindou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Dual 12/15- and 5-Lipoxygenase Deficiency in Macrophages Alters Arachidonic Acid Metabolism and Attenuates Peritonitis and Atherosclerosis in ApoE Knock-out Mice

(2009) Daniel Poeckel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphatidylethanolamine-esterified Eicosanoids in the Mouse

(2009) Alwena H. Morgan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biosynthesis of phosphatidylcholine by human lysophosphatidylcholine acyltransferase 1

(2009) Takeshi Harayama et al.   JOURNAL OF LIPID RESEARCH

Characterization of human lysophospholipid acyltransferase 3

(2009) Shilpa Jain et al.   JOURNAL OF LIPID RESEARCH

Emerging lysophospholipid mediators, lysophosphatidylserine, lysophosphatidylthreonine, lysophosphatidylethanolamine and lysophosphatidylglycerol

(2009) Kumiko Makide et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Identification and Characterization of a Major Liver Lysophosphatidylcholine Acyltransferase

(2008) Yang Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysophospholipid Acyltransferases and Arachidonate Recycling in Human Neutrophils

(2008) Miguel A. Gijón et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acyl-CoA:Lysophospholipid Acyltransferases

(2008) Hideo Shindou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Identification of a Novel Mammalian Brain Isoform of Acyl-CoA:Lysophospholipid Acyltransferase with Prominent Ethanolamine Lysophospholipid Acylating Activity, LPEAT2

(2008) Jingsong Cao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Substrate Preferences of a Lysophosphatidylcholine Acyltransferase Highlight Its Role in Phospholipid Remodeling

(2008) Michael Kazachkov et al.   LIPIDS

Discovery of a lysophospholipid acyltransferase family essential for membrane asymmetry and diversity

(2008) D. Hishikawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caenorhabditis elegans mboa-7, a Member of the MBOAT Family, Is Required for Selective Incorporation of Polyunsaturated Fatty Acids into Phosphatidylinositol

(2007) Hyeon-Cheol Lee et al.   MOLECULAR BIOLOGY OF THE CELL