Virus-mediated decrease of LKB1 activity in the mPFC diminishes stress-induced depressive-like behaviors in mice

Rapid acting antidepressants in the mTOR pathway: Current evidence

(2020) Athira K V et al.   BRAIN RESEARCH BULLETIN

LIMK1/2 in the mPFC Plays a Role in Chronic Stress-Induced Depressive-Like Effects in Mice

(2020) Ting-Ting Gao et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

The impact of chronic stress on energy metabolism

(2020) Michael A. van der Kooij   MOLECULAR AND CELLULAR NEUROSCIENCE

Monoaminergic system and depression

(2019) L. Perez-Caballero et al.   CELL AND TISSUE RESEARCH

The ERK Pathway: Molecular Mechanisms and Treatment of Depression

(2019) John Q. Wang et al.   MOLECULAR NEUROBIOLOGY

A Chronic Immobilization Stress Protocol for Inducing Depression-Like Behavior in Mice

(2019) Hyeonwi Son et al.   Jove-Journal of Visualized Experiments

Hippocampal PPARα is a novel therapeutic target for depression and mediates the antidepressant actions of fluoxetine in mice

(2018) Lu Song et al.   BRITISH JOURNAL OF PHARMACOLOGY

New-Generation, Non-SSRI Antidepressants: Therapeutic Drug Monitoring and Pharmacological Interactions. Part 1: SNRIs, SMSs, SARIs

(2018) Roberto Mandrioli et al.   CURRENT MEDICINAL CHEMISTRY

The antidepressant effects of ɑ-tocopherol are related to activation of autophagy via the AMPK/mTOR pathway

(2018) Xiaoyan Huang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Role of mTOR Complexes in Neurogenesis

(2018) Francesca LiCausi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Gsk3β aggravates the depression symptoms in chronic stress mouse model

(2018) Hong Peng et al.   Journal of Integrative Neuroscience

Mechanisms of ketamine action as an antidepressant

(2018) P Zanos et al.   MOLECULAR PSYCHIATRY

Hippocampal mTOR signaling is required for the antidepressant effects of paroxetine

(2018) Dawei Xu et al.   NEUROPHARMACOLOGY

Neurotrophic factors and neuroplasticity pathways in the pathophysiology and treatment of depression

(2018) Marion J. F. Levy et al.   PSYCHOPHARMACOLOGY

PI3K/AKT/GSK3β/CRMP-2-mediated neuroplasticity in depression induced by stress

(2018) Zuotian Wu et al.   NEUROREPORT

Glucose starvation induces LKB1-AMPK-mediated MMP-9 expression in cancer cells

(2018) Hitoshi Endo et al.   Scientific Reports

Salidroside stimulates the Sirt1/PGC-1α axis and ameliorates diabetic nephropathy in mice

(2018) Haiyan Xue et al.   PHYTOMEDICINE

LKB1 promotes metabolic flexibility in response to energy stress

(2017) Seth J. Parker et al.   METABOLIC ENGINEERING

Molecular neurobiology of mTOR

(2017) Katarzyna Switon et al.   NEUROSCIENCE

Antidepressant action of ketamine via mTOR is mediated by inhibition of nitrergic Rheb degradation

(2016) M M Harraz et al.   MOLECULAR PSYCHIATRY

mTOR-Mediated Regulation of Dendritic Cell Differentiation and Function

(2016) Nyamdelger Sukhbaatar et al.   TRENDS IN IMMUNOLOGY

Implementing guidelines on reporting research using animals (ARRIVE etc.): new requirements for publication in BJP

(2015) John C McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Revisiting the Serotonin Hypothesis: Implications for Major Depressive Disorders

(2015) Marc Fakhoury   MOLECULAR NEUROBIOLOGY

Dendrite pathology and neurodegeneration: focus on mTOR

(2015) AdrianaDi Polo   Neural Regeneration Research

mTOR in Brain Physiology and Pathologies

(2015) Joël Bockaert et al.   PHYSIOLOGICAL REVIEWS

Reactive oxygen species mediate nitric oxide production through ERK/JNK MAPK signaling in HAPI microglia after PFOS exposure

(2015) Cheng Wang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Fluoxetine regulates mTOR signalling in a region-dependent manner in depression-like mice

(2015) Xiao-Long Liu et al.   Scientific Reports

Unpredictable chronic mild stress induces anxiety and depression-like behaviors and inactivates AMP-activated protein kinase in mice

(2014) Shenghua Zhu et al.   BRAIN RESEARCH

The role of mTOR in depression and antidepressant responses

(2014) Helena M. Abelaira et al.   LIFE SCIENCES

Mitochondrial allostatic load puts the 'gluc' back in glucocorticoids

(2014) Martin Picard et al.   Nature Reviews Endocrinology

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces microglial nitric oxide production and subsequent rat primary cortical neuron apoptosis through p38/JNK MAPK pathway

(2013) Yuanye Li et al.   TOXICOLOGY

Dysregulation of mTOR activity through LKB1 inactivation

(2013) Wei Zhou et al.   Chinese Journal of Cancer

Curcumin Attenuates Cardiopulmonary Bypass-Induced Lung Oxidative Damage in Rats

(2012) Kun Liu et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

The role of LKB1 and AMPK in cellular responses to stress and damage

(2011) Angela Alexander et al.   FEBS LETTERS

The neuroprotective action of pyrroloquinoline quinone against glutamate-induced apoptosis in hippocampal neurons is mediated through the activation of PI3K/Akt pathway

(2011) Qi Zhang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

Beyond the serotonin hypothesis: Mitochondria, inflammation and neurodegeneration in major depression and affective spectrum disorders

(2010) Ann Gardner et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

(2010) N. Li et al.   SCIENCE

LKB1 and Mammalian Target of Rapamycin As Predictive Factors for the Anticancer Efficacy of Metformin

(2009) Regan M. Memmott et al.   JOURNAL OF CLINICAL ONCOLOGY

Mitochondrial involvement in psychiatric disorders

(2008) Ling Shao et al.   ANNALS OF MEDICINE