LIMK1/2 in the mPFC Plays a Role in Chronic Stress-Induced Depressive-Like Effects in Mice

Imipramine Ameliorates Depressive Symptoms by Blocking Differential Alteration of Dendritic Spine Structure in Amygdala and Prefrontal Cortex of Chronic Stress-Induced Mice

(2020) Yea-Hyun Leem et al.   Biomolecules & Therapeutics

Hippocampal overexpression of chordin protects against the chronic social defeat stress-induced depressive-like effects in mice

(2020) Cheng-Niu Wang et al.   BRAIN RESEARCH BULLETIN

Altered Connectivity in Depression: GABA and Glutamate Neurotransmitter Deficits and Reversal by Novel Treatments

(2019) Ronald S. Duman et al.   NEURON

Andrographolide exerts significant antidepressant-like effects involving the hippocampal BDNF system in mice

(2019) Jing-Jing Zhang et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Isoflurane produces antidepressant effects inducing BDNF-TrkB signaling in CUMS mice

(2019) Sha-Sha Zhang et al.   PSYCHOPHARMACOLOGY

Baicalin regulates depression behavior in mice exposed to chronic mild stress via the Rac/LIMK/cofilin pathway

(2019) Ye Lu et al.   BIOMEDICINE & PHARMACOTHERAPY

The protective effects of Ghrelin/GHSR on hippocampal neurogenesis in CUMS mice

(2019) Hui-Jie Huang et al.   NEUROPHARMACOLOGY

Chronic social defeat stress induces sustained synaptic structural changes in the prefrontal cortex and amygdala

(2019) L. Colyn et al.   BEHAVIOURAL BRAIN RESEARCH

Hippocampal PPARα is a novel therapeutic target for depression and mediates the antidepressant actions of fluoxetine in mice

(2018) Lu Song et al.   BRITISH JOURNAL OF PHARMACOLOGY

Hippocampal mTOR signaling is required for the antidepressant effects of paroxetine

(2018) Dawei Xu et al.   NEUROPHARMACOLOGY

MiR-134 modulates chronic stress-induced structural plasticity and depression-like behaviors via downregulation of Limk1/cofilin signaling in rats

(2018) Cuiqin Fan et al.   NEUROPHARMACOLOGY

Hippocampal Salt-Inducible Kinase 2 Plays a Role in Depression via the CREB-Regulated Transcription Coactivator 1–cAMP Response Element Binding–Brain-Derived Neurotrophic Factor Pathway

(2018) Bo Jiang et al.   BIOLOGICAL PSYCHIATRY

Effects of Hippocampal LIMK Inhibition on Memory Acquisition, Consolidation, Retrieval, Reconsolidation, and Extinction

(2017) Paula Lunardi et al.   MOLECULAR NEUROBIOLOGY

VGF function in depression and antidepressant efficacy

(2017) C Jiang et al.   MOLECULAR PSYCHIATRY

The Limbic System in Youth Depression: Brain Structural and Functional Alterations in Adolescent In-patients with Severe Depression

(2017) Ronny Redlich et al.   NEUROPSYCHOPHARMACOLOGY

Neural basis of major depressive disorder: Beyond monoamine hypothesis

(2017) Shuken Boku et al.   PSYCHIATRY AND CLINICAL NEUROSCIENCES

Aberrant Rac1-cofilin signaling mediates defects in dendritic spines, synaptic function, and sensory perception in fragile X syndrome

(2017) Alexander Pyronneau et al.   Science Signaling

Aberrant Rac1-cofilin signaling mediates defects in dendritic spines, synaptic function, and sensory perception in fragile X syndrome

(2017) Alexander Pyronneau et al.   Science Signaling

Synaptic Actin Dysregulation, a Convergent Mechanism of Mental Disorders?

(2016) Zhen Yan et al.   JOURNAL OF NEUROSCIENCE

Dendritic Spines in Depression: What We Learned from Animal Models

(2016) Hui Qiao et al.   NEURAL PLASTICITY

Emerging mechanisms and treatments for depression beyond SSRIs and SNRIs

(2015) Elena Dale et al.   BIOCHEMICAL PHARMACOLOGY

Implementing guidelines on reporting research using animals (ARRIVE etc.): new requirements for publication in BJP

(2015) John C McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Roles of LIM kinases in central nervous system function and dysfunction

(2015) H. Cuberos et al.   FEBS LETTERS

Differential induction of FosB isoforms throughout the brain by fluoxetine and chronic stress

(2015) Vincent Vialou et al.   NEUROPHARMACOLOGY

Autism-like Deficits in Shank3-Deficient Mice Are Rescued by Targeting Actin Regulators

(2015) Lara J. Duffney et al.   Cell Reports

Transcriptional profiling of GBM invasion genes identifies effective inhibitors of the LIM kinase-Cofilin pathway

(2015) Jun-Bum Park et al.   Oncotarget

The other side of the coin: Functional and structural versatility of ADF/cofilins

(2014) Gábor Hild et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Shank3 Deficiency Induces NMDA Receptor Hypofunction via an Actin-Dependent Mechanism

(2013) L. J. Duffney et al.   JOURNAL OF NEUROSCIENCE

LIM domain kinases as potential therapeutic targets for neurofibromatosis type 2

(2013) A Petrilli et al.   ONCOGENE

The neurobiology of depression and antidepressant action

(2012) Paul Willner et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Synaptic Dysfunction in Depression: Potential Therapeutic Targets

(2012) R. S. Duman et al.   SCIENCE

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

Branching out: mechanisms of dendritic arborization

(2010) Yuh-Nung Jan et al.   NATURE REVIEWS NEUROSCIENCE

ADF/Cofilin: a functional node in cell biology

(2010) Barbara W. Bernstein et al.   TRENDS IN CELL BIOLOGY

Requirement of AQP4 for Antidepressive Efficiency of Fluoxetine: Implication in Adult Hippocampal Neurogenesis

(2008) Hui Kong et al.   NEUROPSYCHOPHARMACOLOGY