Differential Dual‐Release Bilayer Microneedles Loaded with Aluminum Adjuvants as a Safe and Effective Vaccine Platform

Microneedle Systems for Vaccine Delivery: the story so far

(2021) Md Kamal Hossain et al.   Expert Review of Vaccines

Ceria Nanozyme-Integrated Microneedles Reshape the Perifollicular Microenvironment for Androgenetic Alopecia Treatment

(2021) Anran Yuan et al.   ACS Nano

Microneedle-Mediated Vaccination: Innovation and Translation

(2021) Tao Sheng et al.   ADVANCED DRUG DELIVERY REVIEWS

Considerations in boosting COVID-19 vaccine immune responses

(2021) Philip R Krause et al.   LANCET

Transdermal vaccination via 3D-printed microneedles induces potent humoral and cellular immunity

(2021) Cassie Caudill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Facile Low-Dose Photosensitizer-Incorporated Dissolving Microneedles-Based Composite System for Eliciting Antitumor Immunity and the Abscopal Effect

(2021) Qiong Bian et al.   ACS Nano

Transdermal colorimetric patch for hyperglycemia sensing in diabetic mice

(2020) Zejun Wang et al.   BIOMATERIALS

Long-acting microneedles: a progress report of the state-of-the-art techniques

(2020) Zhongjian Chen et al.   DRUG DISCOVERY TODAY

The COVID-19 vaccine development landscape

(2020) Tung Thanh Le et al.   NATURE REVIEWS DRUG DISCOVERY

A strategic approach to COVID-19 vaccine R&D

(2020) Lawrence Corey et al.   SCIENCE

A Double‐Layered Microneedle Platform Fabricated through Frozen Spray‐Coating

(2020) Xiaoyu Ning et al.   Advanced Healthcare Materials

Prospects for a safe COVID-19 vaccine

(2020) Barton F. Haynes et al.   Science Translational Medicine

Cytokinocytes: the diverse contribution of keratinocytes to immune responses in skin

(2020) Yanyun Jiang et al.   JCI Insight

Transdermal microneedles for the programmable burst release of multiple vaccine payloads

(2020) Khanh T. M. Tran et al.   Nature Biomedical Engineering

Microneedles for painless transdermal immunotherapeutic applications

(2020) Hamed Amani et al.   JOURNAL OF CONTROLLED RELEASE

Vaccine adjuvants: Understanding the structure and mechanism of adjuvanticity

(2019) Shuting Shi et al.   VACCINE

Enhancing humoral immunity via sustained-release implantable microneedle patch vaccination

(2019) Archana V. Boopathy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bio-inspired swellable hydrogel-forming double-layered adhesive microneedle protein patch for regenerative internal/external surgical closure

(2019) Eun Young Jeon et al.   BIOMATERIALS

Microprojection arrays applied to skin generate mechanical stress, induce an inflammatory transcriptome and cell death, and improve vaccine-induced immune responses

(2019) Hwee-Ing Ng et al.   npj Vaccines

Temporal release of a three-component protein subunit vaccine from polymer multilayers

(2019) Divakara S.S.M. Uppu et al.   JOURNAL OF CONTROLLED RELEASE

Immune response to antigen adsorbed to aluminum hydroxide particles: Effects of co-adsorption of ALF or ALFQ adjuvant to the aluminum-antigen complex

(2018) Zoltan Beck et al.   JOURNAL OF CONTROLLED RELEASE

Bioresponsive Microneedles with a Sheath Structure for H2 O2 and pH Cascade-Triggered Insulin Delivery

(2018) Yuqi Zhang et al.   Small

Self-implantable double-layered micro-drug-reservoirs for efficient and controlled ocular drug delivery

(2018) Aung Than et al.   Nature Communications

Multilayered pyramidal dissolving microneedle patches with flexible pedestals for improving effective drug delivery

(2017) Shinying Lau et al.   JOURNAL OF CONTROLLED RELEASE

Non-linear dose-response of aluminium hydroxide adjuvant particles: Selective low dose neurotoxicity

(2017) Guillemette Crépeaux et al.   TOXICOLOGY

Skin immunization by microneedle patch overcomes statin-induced suppression of immune responses to influenza vaccine

(2017) Elena V. Vassilieva et al.   Scientific Reports

Tetanus vaccination with a dissolving microneedle patch confers protective immune responses in pregnancy

(2016) E. Stein Esser et al.   JOURNAL OF CONTROLLED RELEASE

Dissolving Microneedle Delivery of Nanoparticle-Encapsulated Antigen Elicits Efficient Cross-Priming and Th1 Immune Responses by Murine Langerhans Cells

(2015) Marija Zaric et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The immunology of the porcine skin and its value as a model for human skin

(2015) Artur Summerfield et al.   MOLECULAR IMMUNOLOGY

Biopersistence and Brain Translocation of Aluminum Adjuvants of Vaccines

(2015) Romain Kroum Gherardi et al.   Frontiers in Neurology

Polymer multilayer tattooing for enhanced DNA vaccination

(2013) Peter C. DeMuth et al.   NATURE MATERIALS

Mechanism of Immunopotentiation and Safety of Aluminum Adjuvants

(2013) Harm HogenEsch   Frontiers in Immunology

Releasable Layer-by-Layer Assembly of Stabilized Lipid Nanocapsules on Microneedles for Enhanced Transcutaneous Vaccine Delivery

(2012) Peter C. DeMuth et al.   ACS Nano

Disparate adjuvant properties among three formulations of “alum”

(2012) Derek W. Cain et al.   VACCINE

Transcutaneous vaccines: Novel advances in technology and delivery for overcoming the barriers

(2011) Ni Li et al.   VACCINE

Dissolving polymer microneedle patches for influenza vaccination

(2010) Sean P Sullivan et al.   NATURE MEDICINE

The neurotoxicity of environmental aluminum is still an issue

(2010) Stephen C. Bondy   NEUROTOXICOLOGY

The immunobiology of aluminium adjuvants: how do they really work?

(2010) Christopher Exley et al.   TRENDS IN IMMUNOLOGY

New horizons in adjuvants for vaccine development

(2008) Steven G. Reed et al.   TRENDS IN IMMUNOLOGY