Covalent Immune Proximity-Induction Strategy Using SuFEx-Engineered Bifunctional Viral Peptides

Covalent Stabilization of Antibody Recruitment Enhances Immune Recognition of Cancer Targets

(2021) Eden Kapcan et al.   BIOCHEMISTRY

A Genetically Encoded Fluorosulfonyloxybenzoyl-l-lysine for Expansive Covalent Bonding of Proteins via SuFEx Chemistry

(2021) Jun Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Covalent Immune Recruiters (CIRs): Tools To Gain Chemical Control Over Immune Recognition.

(2020) Benjamin Lake et al.   ACS Chemical Biology

Unifying principles of bifunctional, proximity-inducing small molecules

(2020) Christopher J. Gerry et al.   Nature Chemical Biology

Developing Covalent Protein Drugs via Proximity-Enabled Reactive Therapeutics

(2020) Qingke Li et al.   CELL

Fc‐binding antibody‐recruiting molecules targeting prostate‐specific membrane antigen: defucosylation of antibody for efficacy improvement

(2020) Koichi Sasaki et al.   CHEMBIOCHEM

Efficient Innate Immune Killing of Cancer Cells Triggered by Cell Surface Anchoring of Multivalent Antibody-Recruiting Polymers

(2019) Annemiek Uvyn et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Arylfluorosulfate-Based Warheads for Covalent Protein Labeling: A New Addition to the Arsenal

(2018) Pablo Martin-Gago et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemoselective Tyrosine Bioconjugation through Sulfate Click Reaction

(2018) Eun Joung Choi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Introduction of a Crystalline, Shelf-Stable Reagent for the Synthesis of Sulfur(VI) Fluorides

(2018) Hua Zhou et al.   ORGANIC LETTERS

Hapten-mediated recruitment of polyclonal antibodies to tumors engenders antitumor immunity

(2018) Brett Schrand et al.   Nature Communications

Re-engineering the Immune Response to Metastatic Cancer: Antibody-Recruiting Small Molecules Targeting the Urokinase Receptor

(2016) Anthony F. Rullo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Small-molecule PSMA ligands. Current state, SAR and perspectives

(2016) Alexey E. Machulkin et al.   JOURNAL OF DRUG TARGETING

TriKEs and BiKEs join CARs on the cancer immunotherapy highway

(2016) Szun Szun Tay et al.   Human Vaccines & Immunotherapeutics

Site-Selective Solid-Phase Synthesis of a CCR5 Sulfopeptide Library To Interrogate HIV Binding and Entry

(2014) Xuyu Liu et al.   ACS Chemical Biology

Sulfur(VI) Fluoride Exchange (SuFEx): Another Good Reaction for Click Chemistry

(2014) Jiajia Dong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhamnose Glycoconjugates for the Recruitment of Endogenous Anti-Carbohydrate Antibodies to Tumor Cells

(2014) Rachael T. C. Sheridan et al.   CHEMBIOCHEM

Chemical Tools to Monitor and Manipulate the Adaptive Immune System

(2014) Thomas Kodadek   CHEMISTRY & BIOLOGY

Chemically Synthesized Molecules with the Targeting and Effector Functions of Antibodies

(2014) Patrick J. McEnaney et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dissection of the Antibody Response against Herpes Simplex Virus Glycoproteins in Naturally Infected Humans

(2014) T. M. Cairns et al.   JOURNAL OF VIROLOGY

A Comprehensive Mathematical Model for Three-Body Binding Equilibria

(2013) Eugene F. Douglass et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tumor-Associated Macrophages Promote Invasion while Retaining Fc-Dependent Anti-Tumor Function

(2012) K. D. Grugan et al.   JOURNAL OF IMMUNOLOGY

A Chemically Induced Vaccine Strategy for Prostate Cancer

(2011) Anna Dubrovska et al.   ACS Chemical Biology

The Importance of Being Tyrosine: Lessons in Molecular Recognition from Minimalist Synthetic Binding Proteins

(2009) Shohei Koide et al.   ACS Chemical Biology

Chemical Control over Immune Recognition: A Class of Antibody-Recruiting Small Molecules That Target Prostate Cancer

(2009) Ryan P. Murelli et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY