Down-Regulation of Hippocampal Genes Regulating Dopaminergic, GABAergic, and Glutamatergic Function Following Combined Neonatal Phencyclidine and Post-Weaning Social Isolation of Rats as a Neurodevelopmental Model for Schizophrenia

The dopamine D 3 -preferring D 2 /D 3 dopamine receptor partial agonist, cariprazine, reverses behavioural changes in a rat neurodevelopmental model for schizophrenia

(2016) David J.G. Watson et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Early life adversities or high fat diet intake reduce cognitive function and alter BDNF signaling in adult rats: Interplay of these factors changes these effects

(2016) Danusa Mar Arcego et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Linking early-life NMDAR hypofunction and oxidative stress in schizophrenia pathogenesis

(2016) Giles E. Hardingham et al.   NATURE REVIEWS NEUROSCIENCE

Mitochondrial impairment, apoptosis and autophagy in a rat brain as immediate and long-term effects of perinatal phencyclidine treatment — influence of restraint stress

(2016) Gordana Jevtić et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Evaluation of voltage-dependent calcium channel γ gene families identified several novel potential susceptible genes to schizophrenia

(2016) Fanglin Guan et al.   Scientific Reports

Genetic Risk for Schizophrenia: Convergence on Synaptic Pathways Involved in Plasticity

(2015) Jeremy Hall et al.   BIOLOGICAL PSYCHIATRY

Selective disruption of dopamine D2-receptors/beta-arrestin2 signaling by mood stabilizers

(2015) Thomas Del’ Guidice et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Intrinsic Hippocampal Activity as a Biomarker for Cognition and Symptoms in Schizophrenia

(2014) Jason R. Tregellas et al.   AMERICAN JOURNAL OF PSYCHIATRY

The Novel Object Recognition Test in Rodents in Relation to Cognitive Impairment in Schizophrenia

(2014) Lakshmi Rajagopal et al.   CURRENT PHARMACEUTICAL DESIGN

Risperidone inhibits voltage-gated sodium channels

(2014) Jan M. Brauner et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Recent genetic findings in schizophrenia and their therapeutic relevance

(2014) Paul J Harrison   JOURNAL OF PSYCHOPHARMACOLOGY

Chronic Treatment with Mood-Stabilizers Attenuates Abnormal Hyperlocomotion of GluA1-Subunit Deficient Mice

(2014) Milica Maksimovic et al.   PLoS One

Neonatal phencyclidine administration and post-weaning social isolation as a dual-hit model of ‘schizophrenia-like’ behaviour in the rat

(2014) Philip LR Gaskin et al.   PSYCHOPHARMACOLOGY

Prenatal Poly(I:C) Exposure and Other Developmental Immune Activation Models in Rodent Systems

(2013) Urs Meyer   BIOLOGICAL PSYCHIATRY

Impaired GABAergic Inhibition in the Prefrontal Cortex of Early Postnatal Phencyclidine (PCP)-Treated Rats

(2013) C. Kjaerby et al.   CEREBRAL CORTEX

Lamotrigine in Psychiatric Disorders

(2013) Jennifer G. Reid et al.   JOURNAL OF CLINICAL PSYCHIATRY

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

(2013) Stephan Ripke et al.   NATURE GENETICS

Imaging Patients with Psychosis and a Mouse Model Establishes a Spreading Pattern of Hippocampal Dysfunction and Implicates Glutamate as a Driver

(2013) Scott A. Schobel et al.   NEURON

Towards improved animal models for evaluating social cognition and its disruption in schizophrenia: The CNTRICS initiative

(2013) Mark J. Millan et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The atypical antipsychotic risperidone reverses the recognition memory deficits induced by post-weaning social isolation in rats

(2013) Allison L. McIntosh et al.   PSYCHOPHARMACOLOGY

Perinatal phencyclidine administration decreases the density of cortical interneurons and increases the expression of neuregulin-1

(2013) Nevena V. Radonjić et al.   PSYCHOPHARMACOLOGY

In Vivo Neurometabolic Profiling to Characterize the Effects of Social Isolation and Ketamine-Induced NMDA Antagonism: A Rodent Study at 7.0 T

(2013) Antonio Napolitano et al.   SCHIZOPHRENIA BULLETIN

Stress in Puberty Unmasks Latent Neuropathological Consequences of Prenatal Immune Activation in Mice

(2013) S. Giovanoli et al.   SCIENCE

The Nature of Dopamine Dysfunction in Schizophrenia and What This Means for Treatment

(2012) Oliver D. Howes et al.   ARCHIVES OF GENERAL PSYCHIATRY

Post-weaning social isolation rearing influences the expression of molecules related to inhibitory neurotransmission and structural plasticity in the amygdala of adult rats

(2012) Javier Gilabert-Juan et al.   BRAIN RESEARCH

Differential expression of parvalbumin in neonatal phencyclidine-treated rats and socially isolated rats

(2012) Sanne S. Kaalund et al.   JOURNAL OF NEUROCHEMISTRY

A two-hit model: behavioural investigation of the effect of combined neonatal MK-801 administration and isolation rearing in the rat

(2012) Ann Li Lim et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Lamotrigine, a mood stabilizer, may have beneficial effects on memory acquisition and retrieval in mice

(2012) Ipek Komsuoglu Celikyurt et al.   LIFE SCIENCES

Post-weaning social isolation and subchronic NMDA glutamate receptor blockade: Effects on locomotor activity and GABA signaling in the rat suggest independent mechanisms

(2012) Andrea J. Hickey et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Lamotrigine augmentation in patients with schizophrenia who show partial response to clozapine treatment

(2012) Sefa Vayısoğlu et al.   SCHIZOPHRENIA RESEARCH

Animal models of schizophrenia

(2011) CA Jones et al.   BRITISH JOURNAL OF PHARMACOLOGY

Blockade of dopamine D3 but not D2 receptors reverses the novel object discrimination impairment produced by post-weaning social isolation: implications for schizophrenia and its treatment

(2011) David J. G. Watson et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

The Efficacy of Sodium Channel Blockers to Prevent Phencyclidine-Induced Cognitive Dysfunction in the Rat: Potential for Novel Treatments for Schizophrenia

(2011) C. H. Large et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Hippocampal Volume Reduction in First-Episode and Chronic Schizophrenia

(2011) Fulvia Adriano et al.   NEUROSCIENTIST

Spontaneous object recognition and its relevance to schizophrenia: a review of findings from pharmacological, genetic, lesion and developmental rodent models

(2011) L. Lyon et al.   PSYCHOPHARMACOLOGY

Hippocampal dysregulation of dopamine system function and the pathophysiology of schizophrenia

(2011) Daniel J. Lodge et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The Hippocampal Formation in Schizophrenia

(2010) Carol A. Tamminga et al.   AMERICAN JOURNAL OF PSYCHIATRY

Subchronic MK-801 treatment and post-weaning social isolation in rats: Differential effects on locomotor activity and hippocampal long-term potentiation

(2010) Donovan M. Ashby et al.   BEHAVIOURAL BRAIN RESEARCH

Prenatal Interaction of Mutant DISC1 and Immune Activation Produces Adult Psychopathology

(2010) Bagrat Abazyan et al.   BIOLOGICAL PSYCHIATRY

Changes in gene expression after phencyclidine administration in developing rats: a potential animal model for schizophrenia

(2010) F. Liu et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

The Anticonvulsive Drug Lamotrigine Blocks Neuronal  4 2 Nicotinic Acetylcholine Receptors

(2010) C. Zheng et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Lamotrigine blocks the initiation and expression of repeated high-dose methamphetamine-induced prepulse inhibition deficit in rats

(2010) Yasuya Nakato et al.   NEUROSCIENCE LETTERS

Effect of subchronic phencyclidine administration on sucrose preference and hippocampal parvalbumin immunoreactivity in the rat

(2010) Trisha A. Jenkins et al.   NEUROSCIENCE LETTERS

Pharmacological characterization of social isolation-induced hyperactivity

(2010) Katrine Fabricius et al.   PSYCHOPHARMACOLOGY

Gestational methylazoxymethanol acetate administration: A developmental disruption model of schizophrenia

(2009) Daniel J. Lodge et al.   BEHAVIOURAL BRAIN RESEARCH

Effect of pretreatment with risperidone on phencyclidine-induced disruptions in object recognition memory and prefrontal cortex parvalbumin immunoreactivity in the rat

(2009) Claire E. McKibben et al.   BEHAVIOURAL BRAIN RESEARCH

Post-weaning social isolation increases activity in a novel environment but decreases defensive burying and subchronic MK-801 enhances the activity but not the burying effect in rats

(2009) Sarah M. Simpson et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

The Dopamine Hypothesis of Schizophrenia: Version III--The Final Common Pathway

(2009) O. D. Howes et al.   SCHIZOPHRENIA BULLETIN

The efficacy of lamotrigine in clozapine-resistant schizophrenia: A systematic review and meta-analysis

(2009) Jari Tiihonen et al.   SCHIZOPHRENIA RESEARCH

Determinants of everyday outcomes in schizophrenia: The influences of cognitive impairment, functional capacity, and symptoms

(2009) Feea R. Leifker et al.   SCHIZOPHRENIA RESEARCH

Increased expression of the NR2A NMDA receptor subunit in the prefrontal cortex of rats reared in isolation

(2009) Julia J. Turnock-Jones et al.   SYNAPSE

Social isolation rearing-induced impairment of the hippocampal neurogenesis is associated with deficits in spatial memory and emotion-related behaviors in juvenile mice

(2008) Daisuke Ibi et al.   JOURNAL OF NEUROCHEMISTRY

Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database

(2008) Nicole C Allen et al.   NATURE GENETICS

Effects of social isolation rearing on the limbic brain: A combined behavioral and magnetic resonance imaging volumetry study in rats

(2008) M.I. Schubert et al.   NEUROSCIENCE

Behavioural and neurochemical effects of post-weaning social isolation in rodents—Relevance to developmental neuropsychiatric disorders

(2008) Kevin C.F. Fone et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia

(2008) John E. Lisman et al.   TRENDS IN NEUROSCIENCES