Acute Morphine Exposure Increases the Brain Distribution of [18F]DPA-714, a PET Biomarker of Glial Activation in Nonhuman Primates

Got worms? Perinatal exposure to helminths prevents persistent immune sensitization and cognitive dysfunction induced by early-life infection

(2016) Lauren L. Williamson et al.   BRAIN BEHAVIOR AND IMMUNITY

Differential influence of propofol and isoflurane anesthesia in a non-human primate on the brain kinetics and binding of [18F]DPA-714, a positron emission tomography imaging marker of glial activation

(2015) Wadad Saba et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Optimized Quantification of Translocator Protein Radioligand 18F-DPA-714 Uptake in the Brain of Genotyped Healthy Volunteers

(2015) S. Lavisse et al.   JOURNAL OF NUCLEAR MEDICINE

Imaging robust microglial activation after lipopolysaccharide administration in humans with PET

(2015) Christine M. Sandiego et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

[18F]DPA-714 PET imaging of translocator protein TSPO (18 kDa) in the normal and excitotoxically-lesioned nonhuman primate brain

(2014) S. Lavisse et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Adolescent Morphine Exposure Affects Long-Term Microglial Function and Later-Life Relapse Liability in a Model of Addiction

(2013) J. M. Schwarz et al.   JOURNAL OF NEUROSCIENCE

Quantification of the Specific Translocator Protein Signal of 18F-PBR111 in Healthy Humans: A Genetic Polymorphism Effect on In Vivo Binding

(2013) Q. Guo et al.   JOURNAL OF NUCLEAR MEDICINE

Why is neuroimmunopharmacology crucial for the future of addiction research?

(2013) Mark R. Hutchinson et al.   NEUROPHARMACOLOGY

Common and specific liability to addiction: Approaches to association studies of opioid addiction

(2012) David A. Nielsen et al.   DRUG AND ALCOHOL DEPENDENCE

Noninvasive Molecular Imaging of Neuroinflammation

(2012) Andreas H Jacobs et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neuroexcitatory effects of morphine-3-glucuronide are dependent on Toll-like receptor 4 signaling

(2012) Michael R Due et al.   Journal of Neuroinflammation

Opioid Activation of Toll-Like Receptor 4 Contributes to Drug Reinforcement

(2012) M. R. Hutchinson et al.   JOURNAL OF NEUROSCIENCE

Endotoxin-induced systemic inflammation activates microglia: [11C]PBR28 positron emission tomography in nonhuman primates

(2012) Jonas Hannestad et al.   NEUROIMAGE

Implications of central immune signaling caused by drugs of abuse: Mechanisms, mediators and new therapeutic approaches for prediction and treatment of drug dependence

(2012) Janet K. Coller et al.   PHARMACOLOGY & THERAPEUTICS

Morphine activates neuroinflammation in a manner parallel to endotoxin

(2012) X. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

[18F]DPA-714, [18F]PBR111 and [18F]FEDAA1106—Selective radioligands for imaging TSPO 18kDa with PET: Automated radiosynthesis on a TRACERLAb FX-FN synthesizer and quality controls

(2011) Bertrand Kuhnast et al.   APPLIED RADIATION AND ISOTOPES

Initial evaluation in healthy humans of [18F]DPA-714, a potential PET biomarker for neuroinflammation

(2011) Nicolas Arlicot et al.   NUCLEAR MEDICINE AND BIOLOGY

Neurocircuitry of Addiction

(2009) George F Koob et al.   NEUROPSYCHOPHARMACOLOGY

The “Toll” of Opioid-Induced Glial Activation: Improving the Clinical Efficacy of Opioids by Targeting Glia

(2009) Linda R. Watkins et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

DPA-714, a New Translocator Protein-Specific Ligand: Synthesis, Radiofluorination, and Pharmacologic Characterization

(2008) M. L. James et al.   JOURNAL OF NUCLEAR MEDICINE